Alessandro Didonna University of California, San Francisco
51 protocols

Karolina Subrtova Charles University Prague
3 protocols

Wathsala Wijayalath Naval Medical Research Center
6 protocols

Dhaneswar Prusty
  • Faculty, Central University of Rajasthan
Research focus
  • Biochemistry
  • Drug Discovery, Cell Biology and Biochemistry of Malaria parasite (Plasmodium falciparum)


Postdoctoral Studies, McMaster University, Hamilton, Canada, 2015

Lab information

Molecular Parasitology


1.Phenylurenyl benzamide Analogues as a New Anti-malarial Chemotype that Potently Kill Chloroquine Resistant Parasite
Rabindra KC, Prusty D, Selvi BR, Sudarshan D, Dhar SK, Kundu TK Proc Indian Natn Sci Acad 82 No. 1 March 2016 pp. 117-129
(First co-author)

2.The role of palmitoylation for protein recruitment to the inner membrane complex of the malaria parasite.
Wetzel J, Herrmann S, Swapna LS, Prusty D, Peter AT, Kono M, Saini S, NellimarlaS,Wong TW, Wilcke L, Ramsay O, Cabrera A, Biller L, Heincke D,Mossman K, Spielmann T, Ungermann C, Parkinson J, Gilberger TW.J Biol Chem. 2014 Nov 25. pii: jbc.M114.598094.

3.Potent Antimalarial Activity of Acriflavine In Vitro and In Vivo.
Dana S, Prusty D, Dhayal D, Gupta MK, Dar A, Sen S, Mukhopadhyay P, Adak T, Dhar SK.ACS Chem Biol. 2014 Aug 14.
(First co-author)
4.The apicomplexan inner membrane complex. Kono M, Prusty D, Parkinson J, Gilberger TW. Front Biosci (Landmark Ed). 2013 Jun 1;18:982-92. Review.
5.Single-stranded DNA binding protein from human malarial parasite Plasmodium falciparum is encoded in the nucleus and targeted to the apicoplast. Prusty D, Dar A, Priya R, Sharma A, Dana S, Choudhury NR, Rao NS, Dhar SK.Nucleic Acids Res. 2010 Nov;38(20):7037-53. doi: 10.1093/nar/gkq565. Epub 2010 Jun 22.
6.A unique 45-amino-acid region in the toprim domain of Plasmodium falciparum gyrase B is essential for its activity. Dar A, Prusty D, Mondal N, Dhar SK.Eukaryot Cell. 2009 Nov;8(11):1759-69. doi: 10.1128/EC.00149-09. Epub 2009 Aug 21.
7.Nicotinamide inhibits Plasmodium falciparum Sir2 activity in vitro and parasite growth.Prusty D, Mehra P, Srivastava S, Shivange AV, Gupta A, Roy N, Dhar SK.FEMS Microbiol Lett. 2008 May;282(2):266-72. doi: 10.1111/j.1574-6968.2008.01135.x. Epub 2008 Apr

8.The domain structure of Helicobacter pylori DnaB helicase: the N-terminal domain can be dispensable for helicase activity whereas the extreme C-terminal region is essential for its function. Nitharwal RG, Paul S, Dar A, Choudhury NR, Soni RK, Prusty D, Sinha S, Kashav T, Mukhopadhyay G, Chaudhuri TK, Gourinath S, Dhar SK.Nucleic Acids Res. 2007;35(9):2861-74. Epub 2007 Apr 11.
3 Protocols reviewed
Sex-specific Separation of Plasmodium falciparum Gametocyte Populations
Authors:  Melanie C. Ridgway, Daniela Cihalova and Alexander G. Maier, date: 06/05/2021, view: 1251, Q&A: 0

Plasmodium falciparum is a unicellular eukaryotic parasite that causes malaria in humans. The parasite is spread by Anopheles mosquitoes after ingestion of sexual stage parasites known as gametocytes. Malaria transmission depends on parasites

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A Spectrofluorophotometrical Method Based on Fura-2-AM Probe to Determine Cytosolic Ca2+ Level in Pseudomonas syringae Complex Bacterial Cells

Calcium signaling is an emerging mechanism by which bacteria respond to environmental cues. To measure the intracellular free-calcium concentration in bacterial cells, [Ca2+]i, a simple spectrofluorometric method based on the chemical probe Fura

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