Wathsala Wijayalath Naval Medical Research Center
6 protocols

Dhaneswar Prusty
  • Faculty, Central University of Rajasthan
Research focus
  • Biochemistry
  • Drug Discovery, Cell Biology and Biochemistry of Malaria parasite (Plasmodium falciparum)


Postdoctoral Studies, McMaster University, Hamilton, Canada, 2015

Lab information

Molecular Parasitology


1.Phenylurenyl benzamide Analogues as a New Anti-malarial Chemotype that Potently Kill Chloroquine Resistant Parasite
Rabindra KC, Prusty D, Selvi BR, Sudarshan D, Dhar SK, Kundu TK Proc Indian Natn Sci Acad 82 No. 1 March 2016 pp. 117-129
(First co-author)

2.The role of palmitoylation for protein recruitment to the inner membrane complex of the malaria parasite.
Wetzel J, Herrmann S, Swapna LS, Prusty D, Peter AT, Kono M, Saini S, NellimarlaS,Wong TW, Wilcke L, Ramsay O, Cabrera A, Biller L, Heincke D,Mossman K, Spielmann T, Ungermann C, Parkinson J, Gilberger TW.J Biol Chem. 2014 Nov 25. pii: jbc.M114.598094.

3.Potent Antimalarial Activity of Acriflavine In Vitro and In Vivo.
Dana S, Prusty D, Dhayal D, Gupta MK, Dar A, Sen S, Mukhopadhyay P, Adak T, Dhar SK.ACS Chem Biol. 2014 Aug 14.
(First co-author)
4.The apicomplexan inner membrane complex. Kono M, Prusty D, Parkinson J, Gilberger TW. Front Biosci (Landmark Ed). 2013 Jun 1;18:982-92. Review.
5.Single-stranded DNA binding protein from human malarial parasite Plasmodium falciparum is encoded in the nucleus and targeted to the apicoplast. Prusty D, Dar A, Priya R, Sharma A, Dana S, Choudhury NR, Rao NS, Dhar SK.Nucleic Acids Res. 2010 Nov;38(20):7037-53. doi: 10.1093/nar/gkq565. Epub 2010 Jun 22.
6.A unique 45-amino-acid region in the toprim domain of Plasmodium falciparum gyrase B is essential for its activity. Dar A, Prusty D, Mondal N, Dhar SK.Eukaryot Cell. 2009 Nov;8(11):1759-69. doi: 10.1128/EC.00149-09. Epub 2009 Aug 21.
7.Nicotinamide inhibits Plasmodium falciparum Sir2 activity in vitro and parasite growth.Prusty D, Mehra P, Srivastava S, Shivange AV, Gupta A, Roy N, Dhar SK.FEMS Microbiol Lett. 2008 May;282(2):266-72. doi: 10.1111/j.1574-6968.2008.01135.x. Epub 2008 Apr

8.The domain structure of Helicobacter pylori DnaB helicase: the N-terminal domain can be dispensable for helicase activity whereas the extreme C-terminal region is essential for its function. Nitharwal RG, Paul S, Dar A, Choudhury NR, Soni RK, Prusty D, Sinha S, Kashav T, Mukhopadhyay G, Chaudhuri TK, Gourinath S, Dhar SK.Nucleic Acids Res. 2007;35(9):2861-74. Epub 2007 Apr 11.
2 Protocols reviewed
A Spectrofluorophotometrical Method Based on Fura-2-AM Probe to Determine Cytosolic Ca2+ Level in Pseudomonas syringae Complex Bacterial Cells

Calcium signaling is an emerging mechanism by which bacteria respond to environmental cues. To measure the intracellular free-calcium concentration in bacterial cells, [Ca2+]i, a simple spectrofluorometric method based on the chemical probe Fura

More >
Microscopy-based Methods for Rosetting Assay in Malaria Research
Authors:  Wenn-Chyau Lee and Laurent Rénia, date: 07/05/2020, view: 1598, Q&A: 0
In malaria, rosetting phenomenon is a condition where a Plasmodium-infected erythrocyte stably adheres to at least an uninfected erythrocyte. This phenomenon that occurs in all species of human malaria parasite is likely to be an immune ...
More >
We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.