Wayne I Lencer —BIO-PROTOCOL

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Phi Luong GI Cell Biology, Boston Children's Hospital, 2012-2020
1 protocol

Mariska Simpson GI Cell Biology, Boston Children's Hospital, 2018-2020
1 protocol

Daniel Chinnapen Gastroenterology, Boston Childrens Hospital, United States, United States,
1 protocol

Maria Garcia-Castillo Gatroenterology, Boston Children's Hospital, United States, United States,
1 protocol

Wayne I Lencer

Faculty, Gastroenterology, Boston Children's Hospital, Harvard Medical School, USA

Research focus

Cell biology
The Lencer lab studies the cell and molecular biology of polarized epithelial cells lining mucosal surfaces. The projects focus on how barrier epithelial cells interact with the lumenal and sub-epithelial microenvironment, and on the biology of bacterial toxin pathogenesis and mucosal host defense.

2 Author merit
Reviewer merit
Editor merit

Education

Medical School, 1977

Lab information

Lencer Lab

Publications

http://www.ncbi.nlm.nih.gov/pubmed?term=Lencerw

2 Protocols published

A Quantitative Single-cell Flow Cytometry Assay for Retrograde Membrane Trafficking Using Engineered Cholera Toxin

Authors: Mariska S. Simpson, Wayne I. Lencer and Phi Luong, date: 08/05/2020, view: 1285, Q&A: 0

The organization and distribution of proteins, lipids, and nucleic acids in eukaryotic cells is an essential process for cell function. Retrograde trafficking from the plasma membrane to the Golgi and endoplasmic reticulum can greatly modify cell ...

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Transcytosis Assay for Transport of Glycosphingolipids across MDCK-II Cells

Authors: Maria Daniela Garcia-Castillo, Wayne I. Lencer and Daniel J.-F. Chinnapen, date: 10/20/2018, view: 3573, Q&A: 0

Absorption and secretion of peptide and protein cargoes across single-cell thick mucosal and endothelial barriers occurs by active endocytic and vesicular trafficking that connects one side of the epithelial or endothelial cell (the lumen) with the ...

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