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A peer-reviewed protocol journal. No publication fee; no access fee.
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Martin Jinek
2 protocols
Jonathan Hall
1 protocol
Katja Bargsten
1 protocol
Christian Berk
1 protocol
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Gerald Schwank
Gerald Schwank
Research focus
Molecular biology
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1
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1 Protocol published
In vitro
Generation of CRISPR-Cas9 Complexes with Covalently Bound Repair Templates for Genome Editing in Mammalian Cells
Authors:
Nataša Savić
,
Femke CAS Ringnalda
,
Christian Berk
,
Katja Bargsten
,
Jonathan Hall
,
Martin Jinek
and
Gerald Schwank
,
date:
01/05/2019,
view:
6368,
Q&A:
0
The CRISPR-Cas9 system is a powerful genome-editing tool that promises application for gene editing therapies. The Cas9 nuclease is directed to the DNA by a programmable single guide (sg)RNA, and introduces a site-specific double-stranded break ...
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