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Gerald Schwank
  • Gerald Schwank
  • 1 Author merit
1 Protocol published
In vitro Generation of CRISPR-Cas9 Complexes with Covalently Bound Repair Templates for Genome Editing in Mammalian Cells
Authors:  Nataša Savić, Femke CAS Ringnalda, Christian Berk, Katja Bargsten, Jonathan Hall, Martin Jinek and Gerald Schwank, date: 01/05/2019, view: 3053, Q&A: 0
The CRISPR-Cas9 system is a powerful genome-editing tool that promises application for gene editing therapies. The Cas9 nuclease is directed to the DNA by a programmable single guide (sg)RNA, and introduces a site-specific double-stranded break ...
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