Prasanth Manohar
  • Post-Doc, Zhejiang University, Zhejiang University-University of Edinburgh (ZJU-UoE)
Research focus
  • Microbiology
  • Phage therapy, Antibiotic resistance in Gram-negative bacteria, bacteriophage biology

Education

PhD, Vellore Institute of Technology, 2019

Lab information

@Leptihnlab
https://leptihn-lab.org/the-research/

Publications

https://scholar.google.co.in/citations?user=Bd2Eo7YAAAAJ&hl=en
• Manohar P, Loh B, Nachimuthu R, Hua X, Welburn SC, Leptihn C. Secondary bacterial infections in patients with viral pneumonia. Frontiers in Medicine, 2020.
• Archana L, Manohar P, Eniyan K, Jayaraj R, N Ramesh. Evaluation of various phenotypic methods with genotypic screening for detection of methicillin-resistant Staphylococcus aureus. Asian Biomedicine, 13(6), 2020.
• Manohar P, Loh B, Athira S, Nachimuthu R, Hua X, Welburn SC, Leptihn C. Secondary bacterial infections during pulmonary viral diseases: Phage therapeutics as alternatives to antibiotics? Frontiers in Microbiology, 11, 1434, 2020.
• Nachimuthu R, Kannan VR, Bozdogan B, Krishnakumar V, Pandiyan KS, Manohar P. CTX-M-type ESBL-mediated resistance to third-generation cephalosporins and conjugative transfer of resistance in Gram-negative bacteria isolated from hospitals in Tamil Nadu, India. Access Microbiology, 2020.
• Sinha A, Eniyan K, Manohar P, Ramesh N, Bajpai U. Characterization and genome analysis of B1 sub-cluster mycobacteriophage PDRPxv. Virus Research, 197884, 2020.
• Manohar P, Lopes BS, Ramesh N. Dissemination of carbapenem resistance and plasmids-encoding carbapenemases in Gram-negative bacteria isolated from India. BioRxiv, 2020.
• Manohar P and Ramesh N. Improved lyophilization conditions for long-term storage of bacteriophages. Scientific Reports, 2019, 9(1).
• Manohar P, Ashok J Tamhankar, Cecilia Stalsby Lundborg, Nachimuthu Ramesh. Therapeutic characterization and efficacy of bacteriophage cocktails infecting Escherichia coli, Klebsiella pneumoniae and Enterobacter species. Frontiers in Microbiology, 2019; 10, 574.
• Shanthini T, Manohar P, Samna S et al. Emergence of plasmid-borne blaoxa-181 gene in Ochrobactrum intermedium: first report from India. Access Microbiology, 2019
• Ramesh N, Archana L, Royam MM, Manohar P, Eniyan K. Effect of various bacteriological media on the plaque morphology of Staphylococcus and Vibrio phages. Access Microbiology, 2019, 1(4).
• De S, Chaudhuri SR, Panda A, Jadhav GR, Kumar RS, Manohar P, Ramesh N et al. Synthesis, characterisation, molecular docking, biomolecular interaction and cytotoxicity studies of novel ruthenium (ii)–arene-2-heteroarylbenzoxazole complexes. New Journal of Chemistry, 2019.
• Manohar P, Tamhankar A J, Leptihn S, Ramesh N. Pharmacological and immunological aspects of phage therapy. Infectious Microbes & Diseases, 1:2, 2019.
• Manohar P, Ragavi M, Ashby A et al. First report of blaGIM-1 in Acinetobacter variabilis isolated from hospital samples. BioRxiv, 2019.
• Manohar P, Ashok J Tamhankar, Cecilia SL, Ramesh N. Isolation, characterization and in vivo efficacy of Escherichia phage myPSH1131. PLoS One, 2018; 13(10): e0206278.
• Manohar P, Ramesh N, Bruno S Lopes. The therapeutic potential of bacteriophages targeting Gram-negative bacteria using Galleria mellonella infection model. BMC Microbiology, 2018, 18:97.
• Manohar P, Subramanian Babu, Bulent Bozdogan et al. Identification of blaDIM-1 metallo beta-lactamase in Pseudomonas aeruginosa isolated From Tamil Nadu, India. Journal of Global Antimicrobial Resistance, 2018, 13, 7-8.
• Manohar P, Nazia Hassan, Abha Kumari, Vaikhari Kale, Ramesh N. Evaluation of phenotypic methods used for the detection of carbapenemase: modified Hodge test, carbapenem inactivation method, and carbaNP test. Romanian Archives of Microbiology and Immunology. 77 (2), 2018, 141-147.
• Anuradha Ravi, Ekaterina Avershina…. Manohar P, N Ramesh, Kunt Rudi. Comparison of reduced metagenome and 16S rRNA gene sequencing for determination of genetic diversity and mother-child overlap of the gut associated microbiota. Journal of Microbiological Methods, 149, 44-52, 2018.
• Manohar P, Thamaraiselvan Shanthini, Pandey Ekta et al. Colistin-resistant Klebsiella pneumoniae: prevalence of integrons and synergistic out turn for colistin-meropenem. Archives of Clinical Infectious Diseases, 13(1), 2018, e55099.
• Manohar P, Shanthini Thamaraiselvan, Goswami Priyanka et al. Bacterial Load and Contamination of Indian Currency Note: Isolation and Transferability Studies of Multi-Drug Resistant Bacteria. Indian Journal of Public Health Research and Development, 9(9), 2018.
• Manohar P, Thamaraiselvan Shanthini, Reethu Ann Philip et al. Role of biofilm-specific antibiotic resistance genes PA0756-0757, PA5033 and PA2070 in Pseudomonas aeruginosa. BioRxiv, 2018.
• Manohar P, T Shanthini, Ramankannan A et al. The distribution of carbapenem- and colistin- resistance in Gram-negative bacteria from Tamil Nadu region in India. Journal of Medical Microbiology, 2017, 66, 874-883.
• Manohar P, Shanthini T, Nitin Marathe et al. Genetic Characteristics of Plasmid-Mediated Extended Spectrum Beta-Lactamases and Its Coexistence with NDM-1 in Clinical Gram-negative Bacteria. Indian Journal of Biotechnology, 2017, 16(2), 189-194.
• Manohar P, Mahalakshmi D, Aishwariya R, Ramesh N. Antibiotic resistance characteristics of multi-drug resistant Gram-negative bacteria isolated from sewage treatment plants and transferability studies. Biomedicine, 2017, 37(4), 545-550.
• Rajan Choudhary, Manohar P, Jana Vecstaudza et al. Preparation of nanocrystalline forsterite by combustion of different fuels and their comparative in-vitro bioactivity, dissolution behaviour and antibacterial studies. Materials Science and Engineering C, 2017, 77, 811–822.
• Manohar P, T Shanthini, KM Gothandam et al. Enhanced Amylolytic Activity of Intracellular Α-Amylase Produced By Bacillus tequilensis. The Journal of Microbiology, Biotechnology and Food Sciences, 2017, 6 (6). 1314.
• Ramesh Nachimuthu, Manohar P, Shanthini T et al. Nano-antibiotics: A therapeutic future. Nanoscience and Nanotechnology-Asia, 2017, 7 (1), 3-25.
• Anuradha Ravi, Ekaterina Avershina…. Manohar P, Sumathi Padmanaban, Ramesh N, Knut Rudi. Genetic diversity and mother-child overlap of the gut associated microbiota determined by reduced genome sequencing. BioRxiv, 2017.
• Ramesh Nachimuthu….Karthikeyan S, Manohar P, Bülent Bozdogan. Characterization of carbapenem resistant Gram negative bacteria from Tamil Nadu. Journal of Chemotherapy, 2016, 28(5), 371-374.
• Ramesh Nachimuthu, Manohar P, Ramkumar Subramani et al. Colistin susceptibility of Gram-negative clinical isolates in Tamil Nadu, India. Asian Biomedicine, 2016, 10(1), 1-3.
• Manohar P, Gowtham Kumar, Hajarah Hussain, Benedict Paul. Distribution of virulence factors among vancomycin resistance Enterococcus faecalis from dental isolates. Asian Journal of Pharmaceutical and Clinical Research, 9 (3), 2016, 1-3.
• Manohar P, S. Senthilnathan, Benedict paul C, Meera Raju, S. Divakar, S. Abirami, H. Hajarah, K. Uma Harini. Detection of GelE and Factors Affecting Gelatinase Activity of Enterococcus faecalis Isolates. Asian Jr. of Microbiol. Biotech. Env. Sc. 2016, 18 (1), 257-261.
• Manohar P, Bozdogan Bulent, Gothandam KM, Karthikeyan S, Nachimuthu Ramesh. A novel α-amylase producing Bacillus drentensis isolated from coastal mud samples. Asian Journal of Biological and Life Sciences, 2016, 5 (2), 173-178.
• N Ramesh, Akshita Prakash Pillai, Nandini Rajannambiar, Manohar P et al. Prevalence of multi drug resistant strains on touch screen of Automated Teller Machine. Asian Journal of Pharmaceutical and Clinical Research, 2015, 8(2).
• Ramesh N, Manohar P, Avani Patel et al. Screening of CTX-M type extended spectrum beta-lactamases producing clinical isolates from Tamil Nadu. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2015, 6(4), 658-62.
• Murali Vijayan Vijayan….Vinoth Sathasivam, Manohar P, T Shanthini. Microbial Production of Amylase from Cassava Waste. Research in Pharmacy, 2015.
• Manohar P, Nachimuthu Ramesh, Gothandam K.M. et al. Pseudomonas syringae: An overview and its future as a “rain making bacteria”. International Research Journal of Biological Sciences, 2015, 4(2), 70-77.
• N. Ramesh, V. Drishya Nair, H. Karthiayani, M Prasanth et al. Prevalence of blaNDM-1 Among Gram Negative Bacteria from Clinical Samples of Tamil Nadu. International Journal of Medico-biological Research, 2014, 1 (7), 389-393.
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