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Prasanth Manohar
  • Research associate, VIT University
Research focus
  • Microbiology
  • Antibiotic resistance in Gram-negative bacteria, bacteriophages, genome analysis

Education

PhD, Vellore Institute of Technology, 2018

Lab information

drrameshnlab
https://sites.google.com/view/drrameshnlab/home

Publications

1) Prasanth Manohar, Ramesh N, Bruno S Lopes. The therapeutic potential of bacteriophages targeting Gram-negative bacteria using Galleria mellonella infection model. BMC Microbiology. (accepted)
2) Prasanth Manohar, Thamaraiselvan Shanthini, Subramanian Babu et al. Identification of blaDIM-1 metallo beta-lactamase in Pseudomonas aeruginosa isolated From Tamil Nadu, India. Journal of Global Antimicrobial Resistance, 2018, 13, 7-8.
3) Anuradha Ravi, Ekaterina Avershina, Jana Ludvigsen, Inga Leena Angell, Lars-Gustav Snipen, Prasanth Manohar, Nachimuthu Ramesh, Kunt Rudi. Comparison of reduced metagenome and 16S rRNA gene sequencing for determination of genetic diversity and mother-child overlap of the gut associated microbiota. Journal of Microbiological Methods, 2018.
4) Prasanth Manohar, Thamaraiselvan Shanthini, Pandey Ekta et al. Colistin-resistant Klebsiella pneumoniae: prevalence of integrons and synergistic out turn for colistin-meropenem. Archives of Clinical Infectious Diseases, 13(1), 2018, e55099.
5) Prasanth Manohar, T Shanthini, Ramankannan A et al. The distribution of carbapenem- and colistin- resistance in Gram-negative bacteria from Tamil Nadu region in India. Journal of Medical Microbiology, 2017, 66, 874-883.
6) Prasanth Manohar, Shanthini T, Nitin Marathe et al. Genetic Characteristics of Plasmid-Mediated Extended Spectrum Beta-Lactamases and Its Coexistence with NDM-1 in Clinical Gram-negative Bacteria. Indian Journal of Biotechnology, 2017, 16 (2), 189-194.
7) Rajan Choudhary, Prasanth Manohar, Jana Vecstaudza et al. Preparation of nanocrystalline forsterite by combustion of different fuels and their comparative in-vitro bioactivity, dissolution behaviour and antibacterial studies. Materials Science and Engineering C, 2017, 77, 811–822.
8) Anuradha Ravi, Ekaterina Avershina, Inga Leena Angell, Jane Ludvigsen, Prasanth Manohar, Sumathi Padmanaban, Ramesh Nachimuthu, Knut Rudi. Genetic diversity and mother-child overlap of the gut associated microbiota determined by reduced genome sequencing. bioRxiv, 2017.
9) Ramesh Nachimuthu, Ramkumar Subramani, Suresh Maray, Gothandam K.M, Karthikeyan Sivamangala, Prasanth Manohar, Bülent Bozdogan. Characterization of carbapenem resistant Gram negative bacteria from Tamil Nadu. Journal of Chemotherapy, 2016, 28 (5), 371-374.
10) Ramesh Nachimuthu, Manohar Prasanth, Ramkumar Subramani et al. Colistin susceptibility of Gram-negative clinical isolates in Tamil Nadu, India. Asian Biomedicine, 2016, 10(1), 1-3.
11) Ramesh N, Manohar Prasanth, Avani Patel et al. Screening of CTX-M type extended spectrum beta-lactamases producing clinical isolates from Tamil Nadu. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2015, 6(4), 658-62.
12) Prasanth Manohar, Thamaraiselvan Shanthini, Reethu Ann Philip et al. Role of biofilm-specific antibiotic resistance genes PA0756-0757, PA5033 and PA2070 in Pseudomonas aeruginosa. BioRxiv.
Review Articles:
1) Ramesh Nachimuthu, Prasanth Manohar, Shanthini T et al. Nano-antibiotics: A therapeutic future. Nanoscience and Nanotechnology-Asia, 2017, 7 (1), 3-25.
2) Manohar Prasanth, Nachimuthu Ramesh, Gothandam K.M. et al. Pseudomonas syringae: An overview and its future as a “rain making bacteria”. International Research Journal of Biological Sciences, 2015, 4(2), 70-77.
Communicated Articles:
1) Prasanth Manohar and Ramesh N. Isolation and characterization of Escherichia phage myPSH1131. PLOS One.
2) Prasanth Manohar, Ashok J Tamhankar, Cecilia Stalsby Lundborg, Nachimuthu Ramesh. Genomic Characterization of Lytic Bacteriophages of Escherichia coli, Klebsiella pneumoniae and Enterobacter species. Scientific Reports.
3) Prasanth Manohar and Ramesh N. Phage therapy: The choice of stabilizers of lyophilization of bacteriophages for therapy. Scientific Reports.
4) Prasanth Manohar, Thamaraiselvan Shanthini, Bulent Bozdogan et al. Transconjugation of plasmid-bound blaNDM-1 from Staphylococcus sciuri to Escherichia coli: Another possible reason for antibiotic resistance spread. Frontiers in Microbiology.
5) Review: Prasanth Manohar, Ashok .J. Tamhankar, Nachimuthu Ramesh. How well do we know about the immunology and pharmacology of bacteriophages and its importance in phage therapy? 3 Biotech.