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Coauthors
Friedrich Kruse Department of Ophthalmology, University of Erlangen-Nürnberg, Germany, Germany,
2 protocols

Winston Kao Department of Ophthalmology, University of Cincinnati, USA, USA,
2 protocols

Ewa Meyer Department of Ophthalmology, University of Erlangen-Nürnberg, Germany, Germany,
2 protocols

Mindy Call Ophthalmology, University of Cincinnati, USA, USA,
2 protocols

Ursula Schloetzer-Schredhardt
  • Department of Ophthalmology, University of Erlangen-Nürnberg, Germany, Germany,
  • 2 Author merit

Education

Ph.D. in Biology, Department of Biology, University of Erlangen-Nürnberg, Germany

Current position

Associate professor, Department of Ophthalmology, University of Erlangen-Nürnberg, Germany

Publications

  1. Polisetti, N., Sorokin, L., Okumura, N., Koizumi, N., Kinoshita, S., Kruse, F. E. and Schlotzer-Schrehardt, U. (2017). Laminin-511 and -521-based matrices for efficient ex vivo-expansion of human limbal epithelial progenitor cells. Sci Rep 7(1): 5152.
  2. Schlotzer-Schrehardt, U., Freudenberg, U. and Kruse, F. E. (2017). [The emerging technology of tissue engineering : Focus on stem cell niche]. Ophthalmologe 114(4): 327-340.
  3. Mason, S. L., Stewart, R. M., Sheridan, C. M., Keshtkar, F., Rooney, P., Austin, E., Schlotzer-Schrehardt, U., Kruse, F. E. and Kaye, S. B. (2016). Yield and Viability of Human Limbal Stem Cells From Fresh and Stored Tissue. Invest Ophthalmol Vis Sci 57(8): 3708-3713.
  4. Polisetti, N., Zenkel, M., Menzel-Severing, J., Kruse, F. E. and Schlotzer-Schrehardt, U. (2016). Cell Adhesion Molecules and Stem Cell-Niche-Interactions in the Limbal Stem Cell Niche. Stem Cells 34(1): 203-219.
  5. Okumura, N., Kakutani, K., Numata, R., Nakahara, M., Schlotzer-Schrehardt, U., Kruse, F., Kinoshita, S. and Koizumi, N. (2015). Laminin-511 and -521 enable efficient in vitro expansion of human corneal endothelial cells. Invest Ophthalmol Vis Sci 56(5): 2933-2942.
  6. Menzel-Severing, J., Polisetti, N., Schlötzer-Schrehardt, U. and Kruse, F. E. (2015). Towards the use of non-ocular cell lineages in ocular surface disease. In: Scorsetti, D. H., Perez, V. L., Gomes, J. A. P. (Eds.). Stem Cells in Ophthalmology. Jaypee – Highlights Medical Publishers Inc.: pp 179-186.
  7. Petsch, C., Schlotzer-Schrehardt, U., Meyer-Blazejewska, E., Frey, M., Kruse, F. E. and Bachmann, B. O. (2014). Novel collagen membranes for the reconstruction of the corneal surface. Tissue Eng Part A 20(17-18): 2378-2389.
  8. Schlotzer-Schrehardt, U. (2013). Clonal analysis of limbal epithelial stem cell populations. Methods Mol Biol 1014: 55-64.
  9. Menzel-Severing, J., Kruse, F. E. and Schlotzer-Schrehardt, U. (2013). Stem cell-based therapy for corneal epithelial reconstruction: present and future. Can J Ophthalmol 48(1): 13-21.
  10. Schlötzer-Schrehardt, U., Polisetti, N., Menzel-Severing, J. and Kruse, F. E. (2013). Tissue-engineering for reconstruction of the corneal epithelium. In: Holland, E. J., Mannis, M. J. and Lee, W. B. (eds). Ocular Surface Disease: Cornea, Conjunctiva and Tear Film. Elsevier, London, pp 347-360.
  11. Schlötzer-Schrehardt, U. (2013). Clonal analysis of limbal epithelial stem cell populations. In: Wright, B. and Connon, C. J. (eds). Corneal Regenerative Medicine: Methods and Protocols. Chapter 3. Humana Press, New York, pp 55-64.
  12. Menzel-Severing, J., Polisetti, N., Schlotzer-Schrehardt, U. and Kruse, F. (2012). [Limbal stem cells and their niche: implications for bioengineered tissue constructs]. Klin Monbl Augenheilkd 229(12): 1191-1197.
  13. Dietrich-Ntoukas, T., Hofmann-Rummelt, C., Kruse, F. E. and Schlotzer-Schrehardt, U. (2012). Comparative analysis of the basement membrane composition of the human limbus epithelium and amniotic membrane epithelium. Cornea 31(5): 564-569.
  14. Meyer-Blazejewska, E. A., Call, M. K., Yamanaka, O., Liu, H., Schlotzer-Schrehardt, U., Kruse, F. E. and Kao, W. W. (2011). From hair to cornea: toward the therapeutic use of hair follicle-derived stem cells in the treatment of limbal stem cell deficiency. Stem Cells 29(1): 57-66.
  15. Meyer-Blazejewska, E. A., Kruse, F. E., Bitterer, K., Meyer, C., Hofmann-Rummelt, C., Wunsch, P. H. and Schlotzer-Schrehardt, U. (2010). Preservation of the limbal stem cell phenotype by appropriate culture techniques. Invest Ophthalmol Vis Sci 51(2): 765-774.
  16. Blazejewska, E. A., Schlotzer-Schrehardt, U., Zenkel, M., Bachmann, B., Chankiewitz, E., Jacobi, C. and Kruse, F. E. (2009). Corneal limbal microenvironment can induce transdifferentiation of hair follicle stem cells into corneal epithelial-like cells. Stem Cells 27(3): 642-652.
  17. Yeung, A. M., Schlotzer-Schrehardt, U., Kulkarni, B., Tint, N. L., Hopkinson, A. and Dua, H. S. (2008). Limbal epithelial crypt: a model for corneal epithelial maintenance and novel limbal regional variations. Arch Ophthalmol 126(5): 665-669.
  18. Schlotzer-Schrehardt, U., Dietrich, T., Saito, K., Sorokin, L., Sasaki, T., Paulsson, M. and Kruse, F. E. (2007). Characterization of extracellular matrix components in the limbal epithelial stem cell compartment. Exp Eye Res 85(6): 845-860.
  19. Schlotzer-Schrehardt, U. and Kruse, F. E. (2005). Identification and characterization of limbal stem cells. Exp Eye Res 81(3): 247-264.
2 Protocols published
Murine Hair Follicle Derived Stem Cell Transplantation onto the Cornea Using a Fibrin Carrier
The goal of this protocol is to establish a procedure for cultivating stem cells on a fibrin carrier to allow for eventual transplantation to the eye. The ability to transfer stem cells to a patient is critical for treatment for a variety of ...
Hair Follicle Stem Cell Isolation and Expansion
Stem cells are widely used for numerous clinical applications including limbal stem cell deficiency. Stem cell derived from the bulge region of the hair follicle have the ability to differentiate into a variety of cell types including ...