R. Jude Samulski —BIO-PROTOCOL

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Chengwen Li University of North Carolina at Chapel Hill
1 protocol

Zheng Chai Gene Therapy Center, University of North Carolina, Orange, Orange,
1 protocol

R. Jude Samulski

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1 Protocol published

Nab Escaping AAV Mutants Isolated from Mouse Muscles

Authors: Zheng Chai, R. Jude Samulski and Chengwen Li, date: 05/05/2018, view: 2438, Q&A: 0

Neutralizing antibodies (Nabs) are a major challenge in clinical trials of adeno-associated virus (AAV) vector gene therapy, because Nabs are able to inhibit AAV transduction in patients. We have successfully isolated several novel Nab-escaped AAV ...

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