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Mark Webster Biological Sciences, Western Michigan University, USA, USA,
1 protocol

Sarah Webster Biological Sciences, Western Michigan University, USA, USA,
1 protocol

Cindy L. Linn
  • Professor, Biological Sciences, Western Michigan University, USA
Research focus
  • I am a retinal neurobiologist examining neuroprotection and neurogenesis in the adult mammalian retina resulting from activation of alpha7 nicotinic acetylcholine receptors.
  • 1 Author merit

Education

PhD, Rice University, USA, 1990

Lab information

Cindy Linn's Lab
http://www.wmich.edu/biology/directory/linn

Publications

  1. Linn, C. L. (2018). Neuroprotection And/Or Neurogenesis: Effect Of An Alpha7 nAChR Agonist In The Adult Mammalian Retina. J Ophthal Vis Sci 3(1): 1025.
  2. Cooley-Themm, C. A., Ameel, Q., Linn, D. M. and Linn, C. L. (2017). Loss of Displaced Starburst Amacrine Cells in a Rat Glaucoma Model. J Ophthalmic Res Ocular Care 1(1): 28-38.
  3. Webster, M. K., Cooley-Themm, C. A., Barnett, J. D., Bach, H. B., Vainner, J. M., Webster, S. E. and Linn, C. L. (2017). Evidence of BrdU-positive retinal neurons after application of an Alpha7 nicotinic acetylcholine receptor agonist. Neuroscience 346: 437-446. 
  4. Linn, C. L. (2017). Neuroprotection at a retinal synapse: A novel role for starburst amacrine cells. J Ophthal Vis Sci 2(2): 1017.
  5. Linn, C. L. (2016). Retinal ganglion cell neuroprotection induced by activation of alpha7 nicotinic acetylcholine receptors. Neural Regen Res 11(6): 918-919. 
  6. Birkholz, P. J., Gossman, C. A., Webster, M. K., Linn, D. M. and Linn, C. L. (2016). Prevention of glaucomainduced retinal ganglion cell loss using alpha7 nAChR agonists. J Ophthal Vis Sci 1(1): 1003.
  7. Gossman, C. A., Christie, J., Webster, M. K., Linn, D. M. and Linn, C. L. (2016). Neuroprotective Strategies in Glaucoma. Curr Pharm Des 22(14): 2178-2192. 
  8. Gossman, C. A., Linn, D. M. and Linn, C. (2016). Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation. J Vis Exp (109): e53831.
  9. Mata, D., Linn, D. M. and Linn, C. L. (2015). Retinal ganglion cell neuroprotection induced by activation of alpha7 nicotinic acetylcholine receptors. Neuropharmacology 99: 337-346. 
  10. Iwamoto, K., Birkholz, P., Schipper, A., Mata, D., Linn, D. M. and Linn, C. L. (2014). A nicotinic acetylcholine receptor agonist prevents loss of retinal ganglion cells in a glaucoma model. Invest Ophthalmol Vis Sci 55(2): 1078-1087. 
  11. Swartz, M. M., Linn, D. M. and Linn, C. L. (2013). Tropisetron as a neuroprotective agent against glutamate-induced excitotoxicity and mechanisms of action. Neuropharmacology 73: 111-121. 
  12. Iwamoto, K., Mata, D., Linn, D. M. and Linn, C. L. (2013). Neuroprotection of rat retinal ganglion cells mediated through alpha7 nicotinic acetylcholine receptors. Neuroscience 237: 184-198. 
  13. Brandt, S. K., Weatherly, M. E., Ware, L., Linn, D. M. and Linn, C. L. (2011). Calcium preconditioning triggers neuroprotection in retinal ganglion cells. Neuroscience 172: 387-397. 
  14. Asomugha, C. O., Linn, D. M. and Linn, C. L. (2010). ACh receptors link two signaling pathways to neuroprotection against glutamate-induced excitotoxicity in isolated RGCs. J Neurochem 112(1): 214-226. 
  15. Thompson, S. A., Smith, O., Linn, D. M. and Linn, C. L. (2006). Acetylcholine neuroprotection against glutamate-induced excitotoxicity in adult pig retinal ganglion cells is partially mediated through alpha4 nAChRs. Exp Eye Res 83(5): 1135-1145. 
  16. Derbenev, A. V., Linn, C. L. and Guth, P. S. (2005). Muscarinic ACh receptor activation causes transmitter release from isolated frog vestibular hair cells. J Neurophysiol 94(5): 3134-3142. 
1 Protocol published
Eye Drops for Delivery of Bioactive Compounds and BrdU to Stimulate Proliferation and Label Mitotically Active Cells in the Adult Rodent Retina
Authors:  Cindy L. Linn, Sarah E. Webster and Mark K. Webster, date: 11/05/2018, view: 72, Q&A: 0
Eye drop treatments are typically used to apply drugs to the anterior structures of the eye. Recently, however, studies have demonstrated that eye drops can reach the retina in the back of the eye if pharmacological agents are carried in appropriate ...