Nikolai Engedal Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo, Norway, Norway,
2 protocols

Frank Sætre Department of Pathology, Oslo University Hospital and University of Oslo, Norway, Norway,
1 protocol

Morten Luhr
  • Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Oslo, Norway, Norway,
  • 1 Author merit

Education

MSc, University of Oslo, Norway, 2014

Current position

PhD student, Centre for Molecular Medicine Norway, University of Oslo, Norway

Publications

  1. Luhr, M., Szalai, P. and Engedal, N. (2018). The lactate dehydrogenase sequestration assay - A simple and reliable method to determine bulk autophagic sequestration activity in mammalian cells. J Vis Exp (in press).
  2. Vdovikova, S., Luhr, M., Szalai, P., Nygard Skalman, L., Francis, M. K., Lundmark, R., Engedal, N., Johansson, J. and Wai, S. N. (2017). A Novel Role of Listeria monocytogenes Membrane Vesicles in Inhibition of Autophagy and Cell Death. Front Cell Infect Microbiol 7: 154.
  3. Luhr, M., Szalai, P., Saetre, F., Gerner, L., Seglen, P. O. and Engedal, N. (2017). A Simple Cargo Sequestration Assay for Quantitative Measurement of Nonselective Autophagy in Cultured Cells. Methods Enzymol 587: 351-364.
  4. Szalai, P., Hagen, L. K., Saetre, F., Luhr, M., Sponheim, M., Overbye, A., Mills, I. G., Seglen, P. O. and Engedal, N. (2015). Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs. Exp Cell Res 333(1): 21-38.
  5. Seglen, P. O., Luhr, M., Mills, I. G., Saetre, F., Szalai, P. and Engedal, N. (2015). Macroautophagic cargo sequestration assays. Methods 75: 25-36.
  6. Itkonen, H. M., Engedal, N., Babaie, E., Luhr, M., Guldvik, I. J., Minner, S., Hohloch, J., Tsourlakis, M. C., Schlomm, T. and Mills, I. G. (2015). UAP1 is overexpressed in prostate cancer and is protective against inhibitors of N-linked glycosylation. Oncogene 34(28): 3744-3750.
1 Protocol published
The Long-lived Protein Degradation Assay: an Efficient Method for Quantitative Determination of the Autophagic Flux of Endogenous Proteins in Adherent Cell Lines
Authors:  Morten Luhr, Frank Sætre and Nikolai Engedal, date: 05/05/2018, view: 1788, Q&A: 0
Autophagy is a key player in the maintenance of cellular homeostasis in eukaryotes, and numerous diseases, including cancer and neurodegenerative disorders, are associated with alterations in autophagy. The interest for studying autophagy has grown ...
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