Search
Jean-Philippe Girard Institut de Pharmacologie et de Biologie Structurale (IPBS) CNRS, Université de Toulouse UPS, France, France,
1 protocol

Emilie Mirey Institut de Pharmacologie et de Biologie Structurale (IPBS) CNRS, Université de Toulouse UPS, France, France,
1 protocol

Anaïs Duval Institut de Pharmacologie et de Biologie Structurale (IPBS) CNRS, Université de Toulouse UPS, France, France,
1 protocol

Pauline Schmitt Institut de Pharmacologie et de Biologie Structurale (IPBS) CNRS, Université de Toulouse UPS, France, France,
1 protocol

Corinne Cayrol
  • Institut de Pharmacologie et de Biologie Structurale (IPBS) CNRS, Université de Toulouse UPS, France, France,
  • 1 Author merit

Education

PhD in Immunology, University of Toulouse, France, 1992

Current position

Senior researcher at CNRS, Team of JP Girard, Institute of Pharmacology and Structural Biology (IPBS-CNRS), University of Toulouse, France

Publications

  1. Cayrol, C. and Girard, J. P. (2018). Interleukin-33 (IL-33): A nuclear cytokine from the IL-1 family. Immunol Rev 281(1): 154-168. 

  2. Cayrol, C., Duval, A., Schmitt, P., Roga, S., Camus, M., Stella, A., Burlet-Schiltz, O., Gonzalez-de-Peredo, A. and Girard, J.-P. (2018). Environmental allergens induce allergic inflammation through proteolytic maturation of IL-33. Nature Immunology 19(4): 375-385. 

  3. Gautier, V., Cayrol, C., Farache, D., Roga, S., Monsarrat, B., Burlet-Schiltz, O., Gonzalez de Peredo, A. and Girard, J. P. (2016). Extracellular IL-33 cytokine, but not endogenous nuclear IL-33, regulates protein expression in endothelial cells. Sci Rep 6: 34255. 

  4. Lefrancais, E., Duval, A., Mirey, E., Roga, S., Espinosa, E., Cayrol, C. and Girard, J. P. (2014). Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells. Proc Natl Acad Sci U S A 111(43): 15502-15507. 

  5. Cayrol, C. and Girard, J. P. (2014). IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy. Curr Opin Immunol 31: 31-37. 

  6. Lefrancais, E., Roga, S., Gautier, V., Gonzalez-de-Peredo, A., Monsarrat, B., Girard, J. P. and Cayrol, C. (2012). IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G. Proc Natl Acad Sci U S A 109(5): 1673-1678. 

  7. Cayrol, C. and Girard, J. P. (2009). The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proc Natl Acad Sci U S A 106(22): 9021-9026. 

  8. Roussel, L., Erard, M., Cayrol, C. and Girard, J. P. (2008). Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocket. EMBO Rep 9(10): 1006-1012.

1 Protocol published
Isolation and Culture of Mouse Lung ILC2s
Authors:  Pauline Schmitt, Anais Duval, Emilie Mirey, Jean-Philippe Girard and Corinne Cayrol, date: 10/05/2018, view: 354, Q&A: 0
Group 2 Innate Lymphoid Cells (ILC2) play an important role in immune responses at barrier surfaces, notably in the lung during airway allergic inflammation or asthma. Several studies have described methods to isolate ILC2s from wild-type naive ...