Qing-Rong Liu Laboratory of Clinical Investigation, National Institute of Aging - NIH, USA, USA,
1 protocol

Hiroki Ishiguro Psychiatry, University of Yamanashi, Japan, Japan,
1 protocol

Norman Schanz Psychiatry, William Paterson University, USA, USA,
1 protocol

Ana Canseco-Alba Biology, William Paterson University, USA, USA,
1 protocol

Emmanuel S. Onaivi
  • Department of Biology, William Paterson University of New Jersey, USA, USA,
Research focus
  • Neuroscience
  • 1 Author merit


Ph.D in Neuropharmacology, School of Pharmacy, University of Bradford, England, 1987

Current position

Professor, Department of Biology, William Paterson University, Wayne New Jersey, USA

Publications (Since 2013)

  1. Ishiguro, H., Higuchi, S., Arinami, T. and Onaivi, E. S. (2018). Association between alcoholism and the gene encoding the endocannabinoid synthesizing enzyme diacylglycerol lipase alpha in the Japanese population. Alcohol 68: 59-62.
  2. Ishiguro, H., Horiuchi, Y., Tabata, K., Liu, Q. R., Arinami, T. and Onaivi, E. S. (2018). Cannabinoid CB2 Receptor Gene and Environmental Interaction in the Development of Psychiatric Disorders. Molecules 23(8).  
  3. Liu, Q. R., Huang, N. S., Qu, H., O'Connell, J. F., Gonzalez-Mariscal, I., Santa-Cruz-Calvo, S., Doyle, M. E., Xi, Z. X., Wang, Y., Onaivi, E. S. and Egan, J. M. (2018). Identification of novel mouse and rat CB1R isoforms and in silico modeling of human CB1R for peripheral cannabinoid therapeutics. Acta Pharmacol Sin
  4. Perchuk, A., Bierbower, S. M., Canseco-Alba, A., Mora, Z., Tyrell, L., Joshi, N., Schanz, N., Gould, G. G. and Onaivi, E. S. (2018). Developmental and behavioral effects in neonatal and adult mice following prenatal activation of endocannabinoid receptors by capsaicin. Acta Pharmacol Sin
  5. Dang, D. K., Shin, E. J., Mai, A. T., Jang, C. G., Nah, S. Y., Jeong, J. H., Ledent, C., Yamamoto, T., Nabeshima, T., Onaivi, E. S. and Kim, H. C. (2017). Genetic or pharmacological depletion of cannabinoid CB1 receptor protects against dopaminergic neurotoxicity induced by methamphetamine in mice. Free Radic Biol Med 108: 204-224. 
  6. Ishiguro, H. and Onaivi, E. S. (2017). Beyond the Kraepelian dichotomy of schizophrenia and bipolar disorder. J Schizophr Res 4: 1-2.
  7. Liu, Q. R., Canseco-Alba, A., Zhang, H. Y., Tagliaferro, P., Chung, M., Dennis, E., Sanabria, B., Schanz, N., Escosteguy-Neto, J. C., Ishiguro, H., Lin, Z., Sgro, S., Leonard, C. M., Santos-Junior, J. G., Gardner, E. L., Egan, J. M., Lee, J. W., Xi, Z. X. and Onaivi, E. S. (2017). Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference. Sci Rep 7(1): 17410. 
  8. Escosteguy-Neto, J. C., Varela, P., Correa-Neto, N. F., Coelho, L. S., Onaivi, E. S. and Santos-Junior, J. G. (2016). Reconsolidation and update of morphine-associated contextual memory in mice. Neurobiol Learn Mem 130: 194-201. 
  9. Geresu, B., Onaivi, E. and Engidawork, E. (2016). Behavioral evidence for the interaction between cannabinoids and Catha edulis F. (Khat) in mice. Brain Res 1648(Pt A): 333-338. 
  10. Onaivi, E. S., Ishiguro, H. and Liu, Q. R. (2015). Future perspectives: Cannabinoid CB2 receptor ligands and their therapeutic potential in mental diseases. In: Fattore, L. (Ed.) Cannabinoid in Neurologic and Mental Disease. Elsevier
  11. Zhang, H. Y., Bi, G. H., Li, X., Li, J., Qu, H., Zhang, S. J., Li, C. Y., Onaivi, E. S., Gardner, E. L., Xi, Z. X. and Liu, Q. R. (2015). Species differences in cannabinoid receptor 2 and receptor responses to cocaine self-administration in mice and rats. Neuropsychopharmacology 40(4): 1037-1051. 
  12. Connors, K. A., Valenti, T. W., Lawless, K., Sackerman, J., Onaivi, E. S., Brooks, B. W. and Gould, G. G. (2014). Similar anxiolytic effects of agonists targeting serotonin 5-HT1A or cannabinoid CB receptors on zebrafish behavior in novel environments. Aquat Toxicol 151: 105-113. 
  13. Gould, G. G., Burke, T. F., Osorio, M. D., Smolik, C. M., Zhang, W. Q., Onaivi, E. S., Gu, T. T., DeSilva, M. N. and Hensler, J. G. (2014). Enhanced novelty-induced corticosterone spike and upregulated serotonin 5-HT1A and cannabinoid CB1 receptors in adolescent BTBR mice. Psychoneuroendocrinology 39: 158-169.
  14. Onaivi, E. S., Schanz, N. and Lin, Z. C. (2014). Psychiatric disturbances regulate the innate immune system in CSF of conscious mice. Transl Psychiatry 4: e367. 
  15. Yuan Ma, J., Zhi Gu, S., Meng, M., Hui Dang, Y., Ya Huang, C. and Onaivi, E. S. (2014). Regional expression of extracellular signal-regulated kinase 1 and 2 mRNA in a morphine-induced conditioned place preference model. Brain Res 1543: 191-199. 
  16. Onaivi, E., Ishiguro, H., Sgro, S. and M. Leonard, C. (2013). Cannabinoid Receptor Gene Variations in Drug Addiction and Neuropsychiatric Disorders. J Drug Alcohol Res 2: 1-11.
  17. Ishiguro, H., Leonard, C. M., Sgro, S. and Onaivi, E. S. (2013). Cannabinoid receptor gene variations in neuropsychiatric disorders. In: Murillo-Rodriguez, E. (Ed.) Endocannabinoids: Molecular, Pharmacological, Behavioral and Clinical Features. Bentham Science Publishers pp: 3-24.
1 Protocol published
Authors:  Ana Canseco-Alba, Norman Schanz, Hiroki Ishiguro, Qing-Rong Liu and Emmanuel S. Onaivi, date: 10/20/2018, view: 4061, Q&A: 0
The alcohol preference model is one of the most widely used animal models relevant to alcoholism. Stressors increase alcohol consumption. Here we present a protocol for a rapid and useful tool to test alcohol preference and stress-induced alcohol ...
We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.