Emmanuel Pinteaux Division of Neuroscience and Experimental Neurology, Faculty of Biology, Medicine, and Health. University of Manchester, UK, UK,
1 protocol

Stuart Allan Division of Neuroscience and Experimental Neurology. Faculty of Biology, Medicine, and Health. University of Manchester, UK, University of Manchester, United Kingdom
2 protocols

Stuart Cain Wellcome Trust Centre for Cell-Matrix Research, Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine, and Health, University of Manchester, UK, UK,
1 protocol

Jonjo Miller Division of Neuroscience and Experimental Neurology, Faculty of Biology, Medicine, and Health. University of Manchester, UK, UK,
1 protocol

Elena Redondo-Castro
  • Post-Doc, Division of Neuroscience and Experimental Neurology. Faculty of Biology, Medicine, and Health. University of Manchester, UK, University of Manchester, United Kingdom, United Kingdom,
Research focus
  • Neuroscience
  • 1 Author merit

Education

PhD in Neuroscience, Universitat Autònoma de Barcelona, Spain, 2013

Publications

  1. Redondo-Castro, E., Cunningham, C. J., Miller, J., Cain, S.A., Allan, S. M., Pinteaux, E. (2018). Generation of human mesenchymal stem cell 3d spheroids using low-binding plates. (unpublished). 
  2. Cunningham, C. J., Redondo-Castro, E. and Allan, S. M. (2018). The therapeutic potential of the mesenchymal stem cell secretome in ischaemic stroke. J Cereb Blood Flow Metab 38(8): 1276-1292.
  3. Redondo-Castro, E., Cunningham, C. J., Miller, J., Brown, H., Allan, S. M. and Pinteaux, E. (2018). Changes in the secretome of tri-dimensional spheroid-cultured human mesenchymal stem cells in vitro by interleukin-1 priming. Stem Cell Res Ther 9(1): 11. 
  4. Redondo-Castro, E., Faust, D., Fox, S., Baldwin, A. G., Osborne, S., Haley, M. J., Karran, E., Nuthall, H., Atkinson, P. J., Dawson, L. A., Routledge, C., Allan, S. M., Freeman, S., Brownlees, J. and Brough, D. (2018). Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses. Sci Rep 8(1): 5667. 
  5. Faust, D., Fox, S. G., Brough, D., Redondo-Castro, E., Freeman, S., Baldwin, A., Reynolds, D., Atkinson, P., Nuthall, H. N., Karran, E., Dawson, L., Brownlees, J. and Merritt, A. (2017). NOVEL NLRP3 INFLAMMASOME INHIBITORS: EVALUATION IN IL-1β RELEASE AND HIGH-CONTENT ASC-SPECK CELLULAR ASSAYS. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 13(7): P629. 
  6. Redondo-Castro, E., Cunningham, C., Miller, J., Martuscelli, L., Aoulad-Ali, S., Rothwell, N. J., Kielty, C. M., Allan, S. M. and Pinteaux, E. (2017). Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro. Stem Cell Res Ther 8(1): 79.
  7. Abdulaal, W. H., Walker, C. R., Costello, R., Redondo-Castro, E., Mufazalov, I. A., Papaemmanouil, A., Rothwell, N. J., Allan, S. M., Waisman, A., Pinteaux, E. and Muller, W. (2016). Characterization of a conditional interleukin-1 receptor 1 mouse mutant using the Cre/LoxP system. Eur J Immunol 46(4): 912-918. 
  8. Redondo-Castro, E., Navarro, X. and Garcia-Alias, G. (2016). Longitudinal Evaluation of Residual Cortical and Subcortical Motor Evoked Potentials in Spinal Cord Injured Rats. J Neurotrauma 33(10): 907-916. 
  9. Salmeron, K., Aihara, T., Redondo-Castro, E., Pinteaux, E. and Bix, G. (2016). IL-1alpha induces angiogenesis in brain endothelial cells in vitro: implications for brain angiogenesis after acute injury. Journal of Neurochemistry 136(3): 573-580. 
  10. Torres-Espin, A., Redondo-Castro, E., Hernandez, J. and Navarro, X. (2015). Immunosuppression of allogenic mesenchymal stem cells transplantation after spinal cord injury improves graft survival and beneficial outcomes. J Neurotrauma 32(6): 367-380. 
  11. Redondo-Castro, E. and Navarro, X. (2014). Chronic ibuprofen administration reduces neuropathic pain but does not exert neuroprotection after spinal cord injury in adult rats. Exp Neurol 252: 95-103. 
  12. Redondo-Castro, E., Romero, R., Torres-Espin, A., Utrera, J., Duque, D., Junyent, F. and Auladell, C. (2014). Dithiocarb (N,N-diethyldithiocarbamate, DEDTC) decreases levels of biogenic monoamines in the adult mouse brain. Neuropathol Appl Neurobiol 40(6): 747-758. 
  13. Torres-Espin, A., Redondo-Castro, E., Hernandez, J. and Navarro, X. (2014). Bone marrow mesenchymal stromal cells and olfactory ensheathing cells transplantation after spinal cord injury--a morphological and functional comparison in rats. Eur J Neurosci 39(10): 1704-1717. 
  14. Redondo-Castro, E., Garcia-Alias, G. and Navarro, X. (2013). Plastic changes in lumbar segments after thoracic spinal cord injuries in adult rats: an integrative view of spinal nociceptive dysfunctions. Restor Neurol Neurosci 31(4): 411-430. 
  15. Redondo-Castro, E., Hernandez, J., Mahy, N. and Navarro, X. (2013). Phagocytic microglial phenotype induced by glibenclamide improves functional recovery but worsens hyperalgesia after spinal cord injury in adult rats. Eur J Neurosci 38(12): 3786-3798. 
  16. Redondo-Castro, E. and Navarro, X. (2013). Peripheral nerve alterations after spinal cord injury in the adult rat. Spinal Cord 51(8): 630-633. 
  17. Redondo-Castro, E., Torres-Espin, A., Garcia-Alias, G. and Navarro, X. (2013). Quantitative assessment of locomotion and interlimb coordination in rats after different spinal cord injuries. J Neurosci Methods 213(2): 165-178. 
  18. Santos-Nogueira, E., Redondo Castro, E., Mancuso, R. and Navarro, X. (2012). Randall-Selitto test: a new approach for the detection of neuropathic pain after spinal cord injury. J Neurotrauma 29(5): 898-904. 
  19. Redondo Castro, E., Udina, E., Verdu, E. and Navarro, X. (2011). Longitudinal study of wind-up responses after graded spinal cord injuries in the adult rat. Restor Neurol Neurosci 29(2): 115-126.

1 Protocol published
Generation of Human Mesenchymal Stem Cell 3D Spheroids Using Low-binding Plates
The 3D culture of human mesenchymal stem cells (hMSCs) represents a more physiological environment than classical 2D culture and has been used to enhance the MSC secretome or extend cell survival after transplantation. Here we describe a simple and ...
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