Guang Yang Department of Anesthesiology, Perioperative Care and Pain Medicine, New York University School of Medicine, USA, USA,
2 protocols

Joseph Cichon Department of Anesthesiology and Critical Care, University of Pennsylvania, USA, USA,
1 protocol

Linlin Sun
  • Department of Anesthesiology, Perioperative Care and Pain Medicine, New York University School of Medicine, USA, USA,
Research focus
  • Neuroscience
  • 1 Author merit


Ph.D, Peking University/Neuroscience, China, 2013

Current position

Postdoc, Anesthesiology, NYU School of Medicine, US


  1. Sun, L., Zhao, J. Y., Gu, X., Liang, L., Wu, S., Mo, K., Feng, J., Guo, W., Zhang, J., Bekker, A., Zhao, X., Nestler, E. J. and Tao, Y. X. (2017). Nerve injury-induced epigenetic silencing of opioid receptors controlled by DNMT3a in primary afferent neurons. Pain 158(6): 1153-1165.
  2. Sun, L., Lutz B. M., and Tao Y. X., (2016). Contribution of Spinal Cord mTORC1 to Chronic Opioid Tolerance and Hyperalgesia. Book: Neuropathology of Drug Addictions and Substance Misuse: 482-489. 
  3. Sun, L., Lutz, B. M. and Tao, Y. X. (2016). The CRISPR/Cas9 system for gene editing and its potential application in pain research. Transl Perioper Pain Med 1(3): 22-33.
  4. Sun, L., Hu, L., Li, Y. and Cui, C. (2014). Mesoaccumbens dopamine signaling alteration underlies behavioral transition from tolerance to sensitization to morphine rewarding properties during morphine withdrawal. Brain Struct Funct 219(5): 1755-1771.
  5. Li, Z., Gu, X., Sun, L., Wu, S., Liang, L., Cao, J., Lutz, B. M., Bekker, A., Zhang, W. and Tao, Y. X. (2015). Dorsal root ganglion myeloid zinc finger protein 1 contributes to neuropathic pain after peripheral nerve trauma. Pain 156(4): 711-721.
  6. Wang, N., Ge, F., Cui, C., Li, Y., Sun, X., Sun, L., Wang, X., Liu, S., Zhang, H., Liu, Y., Jia, M. and Yang, M. (2017). Role of Glutamatergic Projections from the Ventral CA1 to Infralimbic Cortex in Context-Induced Reinstatement of Heroin Seeking. Neuropsychopharmacology.
  7. Zhao, J. Y., Liang, L., Gu, X., Li, Z., Wu, S., Sun, L., Atianjoh, F. E., Feng, J., Mo, K., Jia, S., Lutz, B. M., Bekker, A., Nestler, E. J. and Tao, Y. X. (2017). DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons. Nat Commun 8: 14712.
  8. Xu, J. T., Sun, L., Lutz, B. M., Bekker, A. and Tao, Y. X. (2015). Intrathecal rapamycin attenuates morphine-induced analgesic tolerance and hyperalgesia in rats with neuropathic pain. Transl Perioper Pain Med 2(2): 27-34.
  9. Li, Y. J., Ping, X. J., Qi, C., Shen, F., Sun, L. L., Sun, X. W., Ge, F. F., Xing, G. G. and Cui, C. L. (2017). Re-exposure to morphine-associated context facilitated long-term potentiation in the vSUB-NAc glutamatergic pathway via GluN2B-containing receptor activation. Addict Biol 22(2): 435-445.
  10. Lv, X. F., Sun, L. L., Cui, C. L. and Han, J. S. (2015). NAc Shell Arc/Arg3.1 Protein Mediates Reconsolidation of Morphine CPP by Increased GluR1 Cell Surface Expression: Activation of ERK-Coupled CREB is Required. Int J Neuropsychopharmacol 18(9).
  11. Hu, L., Chu, N. N., Sun, L. L., Zhang, R., Han, J. S. and Cui, C. L. (2009). Electroacupuncture treatment reverses morphine-induced physiological changes in dopaminergic neurons within the ventral tegmental area. Addict Biol 14(4): 431-437.
1 Protocol published
Authors:  Joseph Cichon, Linlin Sun and Guang Yang, date: 03/20/2018, view: 12014, Q&A: 1
Experimental models of peripheral nerve injury have been developed to study mechanisms of neuropathic pain in living animals. The spared nerve injury (SNI) model in rodents is a partial denervation model, in which the common peroneal and tibial ...
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