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Arun Kumar Ganesan
  • NCI/NIH
Research focus
  • Cancer biology
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Antisense Oligonucleotide-mediated Knockdown in Mammary Tumor Organoids
Authors:  Sarah D. Diermeier and David L. Spector, date: 08/20/2017, view: 2845, Q&A: 0
Primary mammary tumor organoids grown in 3D are an excellent system to study tumor biology. They resemble the organization and physiology of native epithelia more closely than cancer cell lines grown in 2D, and additionally model interactions with the ECM (Boj et al., 2015; Clevers, 2016; Shamir and Ewald, 2014). Mammary tumor organoids ...