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Marco Pirazzini Department of Biomedical Sciences, University of Padova, Italy, Italy,
3 protocols

Aram Megighian Department of Biomedical Sciences, University of Padova, Italy, Italy,
1 protocol

Giulia Zanetti Department of Biomedical Sciences, University of Padova, Italy, Italy,
2 protocols

Paola Caccin Department of Biomedical Sciences, University of Padova, Italy, Italy,
1 protocol

Samuele Negro
  • Department of Biomedical Sciences, University of Padova, Italy, Italy,
  • 2 Author merit

Education

PhD, University of Padova, Italy

Current position

Post Doc, Biomedical Sciences, University of Padova, Italy

Publications

  1. Zanetti, G., Sikorra, S., Rummel, A., Krez, N., Duregotti, E., Negro, S., Henke, T., Rossetto, O., Binz, T. and Pirazzini, M. (2017). Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission. PLoS Pathog 13(8): e1006567.
  2. Negro, S., Lessi, F., Duregotti, E., Aretini, P., La Ferla, M., Franceschi, S., Menicagli, M., Bergamin, E., Radice, E., Thelen, M., Megighian, A., Pirazzini, M., Mazzanti, C. M., Rigoni, M. and Montecucco, C. (2017). CXCL12alpha/SDF-1 from perisynaptic Schwann cells promotes regeneration of injured motor axon terminals. EMBO Mol Med 9(8): 1000-1010.
  3. Rodella, U., Negro, S., Scorzeto, M., Bergamin, E., Jalink, K., Montecucco, C., Yuki, N. and Rigoni, M. (2017). Schwann cells are activated by ATP released from neurons in an in vitro cellular model of Miller Fisher syndrome. Dis Model Mech 10(5): 597-603.
  4. Rodella, U., Scorzeto, M., Duregotti, E., Negro, S., Dickinson, B. C., Chang, C. J., Yuki, N., Rigoni, M. and Montecucco, C. (2016). An animal model of Miller Fisher syndrome: Mitochondrial hydrogen peroxide is produced by the autoimmune attack of nerve terminals and activates Schwann cells. Neurobiol Dis 96: 95-104.
  5. Negro, S., Bergamin, E., Rodella, U., Duregotti, E., Scorzeto, M., Jalink, K., Montecucco, C. and Rigoni, M. (2016). ATP Released by Injured Neurons Activates Schwann Cells. Front Cell Neurosci 10: 134.
  6. Duregotti, E., Negro, S., Scorzeto, M., Zornetta, I., Dickinson, B. C., Chang, C. J., Montecucco, C. and Rigoni, M. (2015). Mitochondrial alarmins released by degenerating motor axon terminals activate perisynaptic Schwann cells. Proc Natl Acad Sci U S A 112(5): E497-505.
2 Protocols published
Electrophysiological Recordings of Evoked End-Plate Potential on Murine Neuro-muscular Synapse Preparations
Authors:  Giulia Zanetti, Samuele Negro, Aram Megighian and Marco Pirazzini, date: 04/20/2018, view: 1350, Q&A: 0
Neuromuscular junction (NMJ) is the specialized chemical synapse that mediates the transmission of the electrical impulse running along motor neuron axons to skeletal muscle fibers. NMJ is the best characterized chemical synapse and its study along ...
Mouse Phrenic Nerve Hemidiaphragm Assay (MPN)
Authors:  Giulia Zanetti, Samuele Negro, Marco Pirazzini and Paola Caccin, date: 03/05/2018, view: 1144, Q&A: 0
The neuromuscular junction (NMJ) is the specialized synapse by which peripheral motor neurons innervate muscle fibers and control skeletal muscle contraction. The NMJ is the target of several xenobiotics, including chemicals, plant, animal and ...