Peipei Guo
  • Faculty, Icahn School of Medicine at Mount Sinai
Research focus
  • Stem cell
  • 1 Author merit


PhD, Cornell University, USA, 2016

Current position

Postdoc, Medicine, Weill Cornell Medicine, USA


  2. Wertheimer, T., Velardi, E., Tsai, J., Cooper, K., Xiao, S., Kloss, C. C., Ottmuller, K. J., Mokhtari, Z., Brede, C., deRoos, P., Kinsella, S., Palikuqi, B., Ginsberg, M., Young, L. F., Kreines, F., Lieberman, S. R., Lazrak, A., Guo, P., Malard, F., Smith, O. M., Shono, Y., Jenq, R. R., Hanash, A. M., Nolan, D. J., Butler, J. M., Beilhack, A., Manley, N. R., Rafii, S., Dudakov, J. A. and van den Brink, M. R. M. (2018). Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration. Sci Immunol 3(19). 
  3. Guo, P. and Rafii, S. (2017). Dangerous Liaisons: Deviant Endothelium NOTCHes toward Tumor Metastasis. Cancer Cell 31(3): 301-303. 
  4. Guo, P., Poulos, M. G., Palikuqi, B., Badwe, C. R., Lis, R., Kunar, B., Ding, B. S., Rabbany, S. Y., Shido, K., Butler, J. M. and Rafii, S. (2017). Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression. J Clin Invest 127(12): 4242-4256. 
  5. Cao, Z., Ding, B. S., Guo, P., Lee, S. B., Butler, J. M., Casey, S. C., Simons, M., Tam, W., Felsher, D. W., Shido, K., Rafii, A., Scandura, J. M. and Rafii, S. (2014). Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance. Cancer Cell 25(3): 350-365. 
  6. Ding, B. S., Cao, Z., Lis, R., Nolan, D. J., Guo, P., Simons, M., Penfold, M. E., Shido, K., Rabbany, S. Y. and Rafii, S. (2014). Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis. Nature 505(7481): 97-102. 
  7. Zhang, X., Zuo, X., Yang, B., Li, Z., Xue, Y., Zhou, Y., Huang, J., Zhao, X., Zhou, J., Yan, Y., Zhang, H., Guo, P., Sun, H., Guo, L., Zhang, Y. and Fu, X. D. (2014). MicroRNA directly enhances mitochondrial translation during muscle differentiation. Cell 158(3): 607-619. 
  8. Aelion Brauer, A., Kedem, A., Lis, R., Guo, P., Rafii, S. and Rosenwaks, Z. (2013). Isolation and characterization of ovarian endothelial cells (ECs): a novel tool in understanding the role of ovarian endothelial cells in reproductive biology. Fertil Steril 100(3): S60-S61.
  9. Aelion Brauer, A., Kedem, A., Guo, P., Wen, D., Ding, B.-S., Liu, H.-C., Rafii, S. and Rosenwaks, Z. (2013). Activated Ovarian Endothelial Cells Promote Early Follicular Development and Survival. Reprod Sci 20: 66A-67A.
  10. Poulos, M. G., Guo, P., Kofler, N. M., Pinho, S., Gutkin, M. C., Tikhonova, A., Aifantis, I., Frenette, P. S., Kitajewski, J., Rafii, S. and Butler, J. M. (2013). Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis. Cell Rep 4(5): 1022-1034.
  11. Ding, B. S., Nolan, D. J., Guo, P., Babazadeh, A. O., Cao, Z., Rosenwaks, Z., Crystal, R. G., Simons, M., Sato, T. N., Worgall, S., Shido, K., Rabbany, S. Y. and Rafii, S. (2011). Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell 147(3): 539-553. 
1 Protocol published
Generation of BMEC Lines and in vitro BMEC-HSPC Co-culture Assays
Authors:  Peipei Guo and Shahin Rafii, date: 11/05/2018, view: 3972, Q&A: 0
Endothelial cells (ECs) sustain the self-renewal and regeneration of adult hematopoietic stem and progenitor cells (HSPCs) via deployment of EC-derived paracrine factors, termed as angiocrine factors. Generation of durable ex vivo vascular ...
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