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A peer-reviewed protocol journal. No publication fee; no access fee.
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R. Samulski
1 protocol
Zheng Chai
Gene Therapy Center, University of North Carolina, Orange, Orange,
1 protocol
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Chengwen Li
University of North Carolina at Chapel Hill
Research focus
Immunology
Contributions
1
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1 Protocol published
Nab Escaping AAV Mutants Isolated from Mouse Muscles
Authors:
Zheng Chai
,
R. Jude Samulski
and
Chengwen Li
,
date:
05/05/2018,
view:
4623,
Q&A:
0
Neutralizing antibodies (Nabs) are a major challenge in clinical trials of adeno-associated virus (AAV) vector gene therapy, because Nabs are able to inhibit AAV transduction in patients. We have successfully isolated several novel Nab-escaped AAV ...
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