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Coauthors
Mohammad Taghi Joghataei Cellular and Molecular Research Center, Iran University of Medical Sciences, Iran, Iran,
1 protocol

Elham Hoveizi Department of Biology, Faculty of Sciences, Shahid Chamran University of Ahvaz, Iran, Iran,
1 protocol

Fereshteh Azedi Department of Neuroscience, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences
1 protocol

Shima Tavakol Cellular and Molecular Research Center, Iran University of Medical Sciences, Iran, Iran,
1 protocol

Jafar Ai
  • Department of Tissue Engineering, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences , Iran, Iran,
  • 1 Author merit

Education

PhD, Shiraz University of Medical Sciences, Iran

Current position

Head of Tissue Engineering and Applied Cell Sciences Department-School of Advanced Technologies in Medicine, Tissue Engineering and Applied Cell Sciences, Tehran University of Medical Sciences, Iran

Publications (since 2016)

  1. Tabatabaei, F. S. and Ai, J. (2017). Mesenchymal endometrial stem/stromal cells for hard tissue engineering: a review of in vitro and in vivo evidence. Regen Med 12(8): 983-995.
  2. Shoae-Hassani, A., Behfar, M., Mortazavi-Tabatabaei, S. A., Ai, J., Mohseni, R. and Hamidieh, A. A. (2017). Natural Killer Cells from the Subcutaneous Adipose Tissue Underexpress the NKp30 and NKp44 in Obese Persons and Are Less Active against Major Histocompatibility Complex Class I Non-Expressing Neoplastic Cells. Front Immunol 8: 1486.
  3. Mohamadi, F., Ebrahimi-Barough, S., Nourani, M. R., Mansoori, K., Salehi, M., Alizadeh, A. A., Tavangar, S. M., Sefat, F., Sharifi, S. and Ai, J. (2017). Enhanced sciatic nerve regeneration by human endometrial stem cells in an electrospun poly (epsilon-caprolactone)/collagen/NBG nerve conduit in rat. Artif Cells Nanomed Biotechnol: 1-13.
  4. Khademi, F., Ai, J., Soleimani, M., Verdi, J., Mohammad Tavangar, S., Sadroddiny, E., Massumi, M. and Mahmoud Hashemi, S. (2017). Improved human endometrial stem cells differentiation into functional hepatocyte-like cells on a glycosaminoglycan/collagen-grafted polyethersulfone nanofibrous scaffold. J Biomed Mater Res B Appl Biomater 105(8): 2516-2529.
  5. Rashtbar, M., Hadjati, J., Ai, J., Shirian, S., Jahanzad, I., Azami, M., Asadpuor, S. and Sadroddiny, E. (2017). Critical-sized full-thickness skin defect regeneration using ovine small intestinal submucosa with or without mesenchymal stem cells in rat model. J Biomed Mater Res B Appl Biomater.
  6. Bahrami, N., Malekolkottab, F., Ebrahimi-Barough, S., Alizadeh Tabari, Z., Hamisi, J., Kamyab, A., Mohamadnia, A., Ai, A., Bayat, F., Bahrami, N. and Ai, J. (2017). The effect of purmorphamine on differentiation of endometrial stem cells into osteoblast-like cells on collagen/hydroxyapatite scaffolds. Artif Cells Nanomed Biotechnol 45(7): 1343-1349.
  7. Salehi, M., Naseri-Nosar, M., Ebrahimi-Barough, S., Nourani, M., Vaez, A., Farzamfar, S. and Ai, J. (2017). Regeneration of sciatic nerve crush injury by a hydroxyapatite nanoparticle-containing collagen type I hydrogel. J Physiol Sci.
  8. Bahrami, N., Bayat, M., Mohamadnia, A., Khakbiz, M., Yazdankhah, M., Ai, J. and Ebrahimi-Barough, S. (2017). Purmorphamine as a Shh Signaling Activator Small Molecule Promotes Motor Neuron Differentiation of Mesenchymal Stem Cells Cultured on Nanofibrous PCL Scaffold. Mol Neurobiol 54(7): 5668-5675.
  9. Terraf, P., Kouhsari, S. M., Ai, J. and Babaloo, H. (2017). Tissue-Engineered Regeneration of Hemisected Spinal Cord Using Human Endometrial Stem Cells, Poly epsilon-Caprolactone Scaffolds, and Crocin as a Neuroprotective Agent. Mol Neurobiol 54(7): 5657-5667.
  10. Kiasatdolatabadi, A., Lotfibakhshaiesh, N., Yazdankhah, M., Ebrahimi-Barough, S., Jafarabadi, M., Ai, A., Sadroddiny, E. and Ai, J. (2017). The Role of Stem Cells in the Treatment of Cerebral Palsy: a Review. Mol Neurobiol 54(7): 4963-4972.
  11. Salehi, M., Naseri-Nosar, M., Ebrahimi-Barough, S., Nourani, M., Khojasteh, A., Farzamfar, S., Mansouri, K. and Ai, J. (2017). Polyurethane/Gelatin Nanofibrils Neural Guidance Conduit Containing Platelet-Rich Plasma and Melatonin for Transplantation of Schwann Cells. Cell Mol Neurobiol.
  12. Sharif, S., Ai, J., Azami, M., Verdi, J., Atlasi, M. A., Shirian, S. and Samadikuchaksaraei, A. (2017). Collagen-coated nano-electrospun PCL seeded with human endometrial stem cells for skin tissue engineering applications. J Biomed Mater Res B Appl Biomater.
  13. Tavakol, S., Musavi, S. M. M., Tavakol, B., Hoveizi, E., Ai, J. and Rezayat, S. M. (2017). Noggin Along with a Self-Assembling Peptide Nanofiber Containing Long Motif of Laminin Induces Tyrosine Hydroxylase Gene Expression. Mol Neurobiol 54(6): 4609-4616.
  14. Soleimannejad, M., Ebrahimi-Barough, S., Soleimani, M., Nadri, S., Tavangar, S. M., Roohipoor, R., Yazdankhah, M., Bayat, N., Riazi-Esfahani, M. and Ai, J. (2017). Fibrin gel as a scaffold for photoreceptor cells differentiation from conjunctiva mesenchymal stem cells in retina tissue engineering. Artif Cells Nanomed Biotechnol: 1-10.
  15. Salehi, M., Naseri-Nosar, M., Ebrahimi-Barough, S., Nourani, M., Khojasteh, A., Hamidieh, A. A., Amani, A., Farzamfar, S. and Ai, J. (2017). Sciatic nerve regeneration by transplantation of Schwann cells via erythropoietin controlled-releasing polylactic acid/multiwalled carbon nanotubes/gelatin nanofibrils neural guidance conduit. J Biomed Mater Res B Appl Biomater.
  16. Mohamadi, F., Ebrahimi-Barough, S., Reza Nourani, M., Ali Derakhshan, M., Goodarzi, V., Sadegh Nazockdast, M., Farokhi, M., Tajerian, R., Faridi Majidi, R. and Ai, J. (2017). Electrospun nerve guide scaffold of poly(epsilon-caprolactone)/collagen/nanobioglass: an in vitro study in peripheral nerve tissue engineering. J Biomed Mater Res A 105(7): 1960-1972.
  17. Ghorbani, M., Ai, J., Nourani, M. R., Azami, M., Hashemi Beni, B., Asadpour, S. and Bordbar, S. (2017). Injectable natural polymer compound for tissue engineering of intervertebral disc: In vitro study. Mater Sci Eng C Mater Biol Appl 80: 502-508.
  18. Kargozar, S., Lotfibakhshaiesh, N., Ai, J., Mozafari, M., Brouki Milan, P., Hamzehlou, S., Barati, M., Baino, F., Hill, R. G. and Joghataei, M. T. (2017). Strontium- and cobalt-substituted bioactive glasses seeded with human umbilical cord perivascular cells to promote bone regeneration via enhanced osteogenic and angiogenic activities. Acta Biomater 58: 502-514.
  19. Davoudi, P., Assadpour, S., Derakhshan, M. A., Ai, J., Solouk, A. and Ghanbari, H. (2017). Biomimetic modification of polyurethane-based nanofibrous vascular grafts: A promising approach towards stable endothelial lining. Mater Sci Eng C Mater Biol Appl 80: 213-221.
  20. Bayat, N., Ebrahimi-Barough, S., Norouzi-Javidan, A., Saberi, H., Ardakan, M. M. M., Ai, A., Soleimannejad, M. and Ai, J. (2017). Anti-inflammatory Effects of Atorvastatin by Suppressing TRAF3IP2 and IL-17RA in Human Glioblastoma Spheroids Cultured in a Three-dimensional Model: Possible Relevance to Glioblastoma Treatment. Mol Neurobiol.
  21. Ebrahimi-Barough, S., Hoveizi, E., Yazdankhah, M., Ai, J., Khakbiz, M., Faghihi, F., Tajerian, R. and Bayat, N. (2017). Inhibitor of PI3K/Akt Signaling Pathway Small Molecule Promotes Motor Neuron Differentiation of Human Endometrial Stem Cells Cultured on Electrospun Biocomposite Polycaprolactone/Collagen Scaffolds. Mol Neurobiol 54(4): 2547-2554.
  22. Tavakol, S., Mousavi, S. M. M., Tavakol, B., Hoveizi, E., Ai, J. and Sorkhabadi, S. M. R. (2017). Mechano-Transduction Signals Derived from Self-Assembling Peptide Nanofibers Containing Long Motif of Laminin Influence Neurogenesis in In-Vitro and In-Vivo. Mol Neurobiol 54(4): 2483-2496.
  23. Soleimannejad, M., Ebrahimi-Barough, S., Nadri, S., Riazi-Esfahani, M., Soleimani, M., Tavangar, S. M. and Ai, J. (2017). Retina tissue engineering by conjunctiva mesenchymal stem cells encapsulated in fibrin gel: Hypotheses on novel approach to retinal diseases treatment. Med Hypotheses 101: 75-77.
  24. Ebrahimi, M., Ai, J., Biazar, E., Faridi-Majidi, R., Hajati, J. and Ebrahimi-Barough, S. (2017). Investigation of properties of chemically cross-linked silk nanofibrous mat as a nerve guide. Materials Technology 1-9.
  25. Rashtbar, M., Hadjati, J., Ai, J., Jahanzad, I., Azami, M., Shirian, S., Ebrahimi-Barough, S. and Sadroddiny, E. (2017). Characterization of decellularized ovine small intestine submucosal layer as extracellular matrix-based scaffold for tissue engineering. J Biomed Mater Res B Appl Biomater.
  26. Kouchesfahani, H. M., Ebrahimi-Barough, S., Ai, J. and Rahimi, A. (2017). Differentiation of endometrial stem cells into motor neurons by the use of purmorphamin small molecule. Tehran University Medical Journal TUMS Publications 74 (12): 861-868.
  27. Bayat, N., Ebrahimi-Barough, S., Norouzi-Javidan, A., Saberi, H., Ardakan, M. M. M., Ai, A., Soleimannejad, M. and Ai, J. (2017). Anti-inflammatory Effects of Atorvastatin by Suppressing TRAF3IP2 and IL-17RA in Human Glioblastoma Spheroids Cultured in a Three-dimensional Model: Possible Relevance to Glioblastoma Treatment. Mol Neurobiol.
  28. Shamosi, A., Mehrabani, D., Azami, M., Ebrahimi-Barough, S., Siavashi, V., Ghanbari, H., Sharifi, E., Roozafzoon, R. and Ai, J. (2017). Differentiation of human endometrial stem cells into endothelial-like cells on gelatin/chitosan/bioglass nanofibrous scaffolds. Artif Cells Nanomed Biotechnol 45(1): 163-173.
  29. Ebrahimi, L., Ai, J., Alizadeh, A. and Shariaty, M. (2017). Imminent Angiotensin-converting Enzyme Inhibitor from Microbial Source for Cancer Therapy. Int J Prev Med 8: 80.
  30. Sayehmiri, F., Alikhani, M. Y., Sayehmiri, K., Karami, M. and Ghaderkhani, J. (2017). The Prevalence of Antibiotic Resistance to Polymyxins in Clinical Isolates of Acinetobacter baumannii in Iran and the World: A Systematic Review and Meta-Analysis. Prevalence 26: 11.
  31. Bayat, N., Ebrahimi-Barough, S., Norouzi-Javidan, A., Saberi, H., Tajerian, R., Ardakan, M. M. M., Shirian, S., Ai, A. and Ai, J. (2016). Apoptotic effect of atorvastatin in glioblastoma spheroids tumor cultured in fibrin gel. Biomed Pharmacother 84: 1959-1966.
  32. Hao, H., Shao, J., Deng, Y., He, S., Luo, F., Wu, Y., Li, J., Tan, H., Li, J. and Fu, Q. (2016). Synthesis and characterization of biodegradable lysine-based waterborne polyurethane for soft tissue engineering applications. Biomater Sci 4(11): 1682-1690.
  33. Asadpour, S., Ghanbari, H. and Ai, J., (2016). The Behavior of Cardiomyoblast Cells on Silk Fibroin/Gelatin/Chitosan Scaffolds. TISSUE ENGINEERING PART A 22: S131-S131.
  34. Heidari-Keshel, S., Rezaei-Tavirani, M., Ai, J., Soleimani, M. and Ebrahimi, M. (2016). Purification and identification of CD146 positive endometrial somatic stem cell from human normal endometrium biopsy and gene expression criteria. MINERVA BIOTECNOLOGICA 28(4): 208-218.
  35. Barabadi, Z., Azami, M., Sharifi, E., Karimi, R., Lotfibakhshaiesh, N., Roozafzoon, R., Joghataei, M. T. and Ai, J. (2016). Fabrication of hydrogel based nanocomposite scaffold containing bioactive glass nanoparticles for myocardial tissue engineering. Mater Sci Eng C Mater Biol Appl 69: 1137-1146.
  36. Rezapour-Lactoee, A., Yeganeh, H., Ostad, S. N., Gharibi, R., Mazaheri, Z. and Ai, J. (2016). Thermoresponsive polyurethane/siloxane membrane for wound dressing and cell sheet transplantation: In-vitro and in-vivo studies. Mater Sci Eng C Mater Biol Appl 69: 804-814.
  37. Bayat, N., Ebrahimi-Barough, S., Ardakan, M. M., Ai, A., Kamyab, A., Babaloo, N. and Ai, J. (2016). Differentiation of Human Endometrial Stem Cells into Schwann Cells in Fibrin Hydrogel as 3D Culture. Mol Neurobiol 53(10): 7170-7176.
  38. Milan, P. B., Lotfibakhshaiesh, N., Joghataie, M. T., Ai, J., Pazouki, A., Kaplan, D. L., Kargozar, S., Amini, N., Hamblin, M. R., Mozafari, M. and Samadikuchaksaraei, A. (2016). Accelerated wound healing in a diabetic rat model using decellularized dermal matrix and human umbilical cord perivascular cells. Acta Biomater 45: 234-246.
  39. Terraf, P., Ai, J., Kouhsari, S. and Babaloo, H. (2016). Indirect co-culture with schwann cells as a new approach for human endometrial stem cells neural transdifferentia tion. Int J Stem Cell Res Transplant 4(8): 235-242.
  40. Kargozar, S., Lotfibakhshaiesh, N., Ai, J., Samadikuchaksaraie, A. and Hill, R. G. (2016). Synthesis, physico-chemical and biological characterization of strontium and cobalt substituted bioactive glasses for bone tissue engineering. Journal of Non-Crystalline Solids 449: 133-140.
  41. Tavakol, S., Saber, R., Hoveizi, E., Tavakol, B., Aligholi, H., Ai, J. and Rezayat, S. M. (2016). Self-Assembling Peptide Nanofiber Containing Long Motif of Laminin Induces Neural Differentiation, Tubulin Polymerization, and Neurogenesis: In Vitro, Ex Vivo, and In Vivo Studies. Mol Neurobiol 53(8): 5288-5299.
  42. Shirian, S., Ebrahimi-Barough, S., Saberi, H., Norouzi-Javidan, A., Mousavi, S. M., Derakhshan, M. A., Arjmand, B. and Ai, J. (2016). Comparison of Capability of Human Bone Marrow Mesenchymal Stem Cells and Endometrial Stem Cells to Differentiate into Motor Neurons on Electrospun Poly(epsilon-caprolactone) Scaffold. Mol Neurobiol 53(8): 5278-5287.
  43. Sharifi, E., Ebrahimi-Barough, S., Panahi, M., Azami, M., Ai, A., Barabadi, Z., Kajbafzadeh, A. M. and Ai, J. (2016). In vitro evaluation of human endometrial stem cell-derived osteoblast-like cells' behavior on gelatin/collagen/bioglass nanofibers' scaffolds. J Biomed Mater Res A 104(9): 2210-2219.
  44. Mirzaei, E., Ai, J., Ebrahimi-Barough, S., Verdi, J., Ghanbari, H. and Faridi-Majidi, R. (2016). The Differentiation of Human Endometrial Stem Cells into Neuron-Like Cells on Electrospun PAN-Derived Carbon Nanofibers with Random and Aligned Topographies. Mol Neurobiol 53(7): 4798-4808.
  45. Derakhshan, M. A., Pourmand, G., Ai, J., Ghanbari, H., Dinarvand, R., Naji, M. and Faridi-Majidi, R. (2016). Electrospun PLLA nanofiber scaffolds for bladder smooth muscle reconstruction. Int Urol Nephrol 48(7): 1097-1104.
  46. Tavakol, S., Saber, R., Hoveizi, E., Aligholi, H., Ai, J. and Rezayat, S. M. (2016). Chimeric Self-assembling Nanofiber Containing Bone Marrow Homing Peptide's Motif Induces Motor Neuron Recovery in Animal Model of Chronic Spinal Cord Injury; an In Vitro and In Vivo Investigation. Mol Neurobiol 53(5): 3298-3308.
  47. Barabadi, Z., Sharifi, E., Azami, M. and Ai, J. (2016). Copper-doped 45S5 bioglass nanoparticles for tissue engineering applications: A comparative study. Biointerface Research in Applied Chemistry 6(3).
  48. Bagher, Z., Azami, M., Ebrahimi-Barough, S., Mirzadeh, H., Solouk, A., Soleimani, M., Ai, J., Nourani, M. R. and Joghataei, M. T. (2016). Differentiation of Wharton's Jelly-Derived Mesenchymal Stem Cells into Motor Neuron-Like Cells on Three-Dimensional Collagen-Grafted Nanofibers. Mol Neurobiol 53(4): 2397-2408.
  49. Faghihi, F., Mirzaei, E., Ai, J., Lotfi, A., Sayahpour, F. A., Barough, S. E. and Joghataei, M. T. (2016). Differentiation Potential of Human Chorion-Derived Mesenchymal Stem Cells into Motor Neuron-Like Cells in Two- and Three-Dimensional Culture Systems. Mol Neurobiol 53(3): 1862-1872.
  50. Shafiee, A., Kabiri, M., Langroudi, L., Soleimani, M. and Ai, J. (2016). Evaluation and comparison of the in vitro characteristics and chondrogenic capacity of four adult stem/progenitor cells for cartilage cell-based repair. J Biomed Mater Res A 104(3): 600-610.
  51. Sharifi, E., Azami, M., Kajbafzadeh, A. M., Moztarzadeh, F., Faridi-Majidi, R., Shamousi, A., Karimi, R. and Ai, J. (2016). Preparation of a biomimetic composite scaffold from gelatin/collagen and bioactive glass fibers for bone tissue engineering. Mater Sci Eng C Mater Biol Appl 59: 533-541.
  52. Saberi, H., Derakhshanrad, N., Arjmand, B., Ai, J., Soleymani, M. and Hamidieh, A. A. (2016). Regulations and ethical codes for clinical cell therapy trials in Iran. Translational Neuroscience and Clinics 1(2): 110-113.
  53. Alizadeh, A., Moztarzadeh, F., Ostad, S. N., Azami, M., Geramizadeh, B., Hatam, G., Bizari, D., Tavangar, S. M., Vasei, M. and Ai, J. (2016). Synthesis of calcium phosphate-zirconia scaffold and human endometrial adult stem cells for bone tissue engineering. Artif Cells Nanomed Biotechnol 44(1): 66-73.
  54. Bayat, N., Ebrahimi-Barough, S., Ardakan, M. M., Ai, A., Kamyab, A., Babaloo, N. and Ai, J. (2016). Differentiation of Human Endometrial Stem Cells into Schwann Cells in Fibrin Hydrogel as 3D Culture. Mol Neurobiol 53(10): 7170-7176.
  55. Kouchesfahani, H. M., Barough, S. E., Ai, J. and Anbar, H. (2016). Endometrial stem cells differentiation into neural cells by Ly294002 small molecule. Koomesh 18(1).
  56. Ebrahimi-Barough, S., Rahbarghazi, R., Bagher, Z., Ai, J. and Hoveizi, E. (2016). Current Understanding Realities of Umbilical Cord Stem Cells Biology and Future Perspectives in Clinical Application. Perinatal Tissue-Derived Stem Cells 107-136. 
1 Protocol published
Human Endometrial Stem Cell Isolation from Endometrium and Menstrual Blood
Authors:  Shima Tavakol, Freshteh Azedi, Elham Hoveizi, Jafar Ai and Mohammad Taghi Joghataei, date: 01/20/2018, view: 1633, Q&A: 0
Human endometrial stem cell/stromal cells (hEnSCs) are isolated from endometrium or menstrual blood and are recognized as a valuable cell type in tissue engineering and cell therapy. Furthermore, hEnSCs, which have CD90 (a mesenchymal marker), CD105 ...