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Coauthors
Marianne Spalinger Department for Gastroenterology and Hepatology, University Hospital Zürich, Switzerland, Switzerland,
1 protocol

Michael Scharl
  • Department for Gastroenterology and Hepatology, University Hospital Zürich, Switzerland, Switzerland,
  • 1 Author merit

Education

Professor, University of Zürich, Switzerland

Current position

Head of Research, Department of Gastroenterology and Hepatology, University Hospital Zürich, University of Zürich, Switzerland

Publications

  1. https://www.ncbi.nlm.nih.gov/pubmed/?term=scharl+m
1 Protocol published
Mono Sodium Urate Crystal-induced Peritonitis for in vivo Assessment of Inflammasome Activation
Authors:  Marianne R. Spalinger and Michael Scharl, date: 03/05/2018, view: 1125, Q&A: 0
Due to its particulate material, mono-sodium urate (MSU) crystals are potent activators of the NOD-like receptor NLRP3. Upon activation, NLRP3 induces the formation of inflammasome complexes, which lead to the production and release of mature IL-1β. ...