Corrado Di Natale Department of Electronic Engineering, University of Rome Tor Vergata, Italy, Italy,
1 protocol

Federica Sangiuolo Department of Biomedicine and Prevention, University of Rome Tor Vergata, Italy, Italy,
1 protocol

Novelli Giuseppe Department of Biomedicine and Prevention, University of Rome Tor Vergata, Italy, Italy,
1 protocol

Paolesse Roberto Department of Chemical Science and Technology, University of Rome Tor Vergata, Italy, Italy,
1 protocol

Paola Spitalieri
  • Department of Biomedicine and Prevention, University of Rome Tor Vergata, Italy, Italy,
  • 1 Author merit

Education

Degree in Biological Sciences , University of Rome, La Sapienza, Italia

Current position

Research, via Montpellier,1, Tor Vergata University of Rome, Italia

Publications (since 2008)

  1. Spitalieri, P., Salehi, L. B., Mango, R., Gigante, L., Postorivo, D., Nardone, A. M., Orlandi, A., Luciano, S., Ta¬larico, R. V., Novelli, G. and Sangiuolo, F. (2017). Two Novel Cases of Marfan Syndrome with FBN1 whole Gene Deletion: Laboratory Assay and Cases Review. J Genet Mutat Disor 1(1):102.
  2. Capuano, R., Spitalieri, P., Talarico, R. V., Domakoski, A. C., Catini, A., Paolesse, R., Martinelli, E., Novelli, G., Sangiuolo, F. and Di Natale, C. (2017). A preliminary analysis of volatile metabolites of human induced pluripotent stem cells along the in vitro differentiation. Sci Rep 7(1): 1621.
  3. Talarico, R. V., Novelli, G., Sangiuolo, F. and Spitalieri, P. (2017). Human Induced Pluripotent Stem Cells-Based Strategies: New Frontiers for Personalized Medicine. Toward the Future: the New Challenges of the Cell Therapy and Potential of Regenerative Medicine (6): 105-140.
  4. Murdocca, M., Ciafre, S. A., Spitalieri, P., Talarico, R. V., Sanchez, M., Novelli, G. and Sangiuolo, F. (2016). SMA Human iPSC-Derived Motor Neurons Show Perturbed Differentiation and Reduced miR-335-5p Expression. Int J Mol Sci 17(8).
  5. Burla, R., Carcuro, M., Torre, M. L., Fratini, F., Crescenzi, M., D'Apice, M. R., Spitalieri, P., Raffa, G. D., Astrologo, L., Lattanzi, G., Cundari, E., Raimondo, D., Biroccio, A., Gatti, M. and Saggio, I. (2016). The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence. Open Biol 6(8).
  6. Spitalieri, P., Talarico, V. R., Murdocca, M., Novelli, G. and Sangiuolo, F. (2016). Human induced pluripotent stem cells for monogenic disease modelling and therapy. World J Stem Cells 8(4): 118-135.
  7. Spitalieri, P., Talarico, R. V., Botta, A., Murdocca, M., D'Apice, M. R., Orlandi, A., Giardina, E., Santoro, M., Brancati, F., Novelli, G. and Sangiuolo, F. (2015). Generation of Human Induced Pluripotent Stem Cells from Extraembryonic Tissues of Fetuses Affected by Monogenic Diseases. Cell Reprogram 17(4): 275-287.
  8. Massimiani, M., Vecchione, L., Piccirilli, D., Spitalieri, P., Amati, F., Salvi, S., Ferrazzani, S., Stuhlmann, H. and Campagnolo, L. (2015). Epidermal growth factor-like domain 7 promotes migration and invasion of human trophoblast cells through activation of MAPK, PI3K and NOTCH signaling pathways. Mol Hum Reprod 21(5): 435-451.
  9. Spitalieri, P., Talarico, V., Luchetti, A., Brancati, F., Botta, A., Novelli, G. and Sangiuolo, F. (2014). Generation of disease specific induced pluripotent stem cells from human fetal extra-embryonic tissues. Cytotherapy Suppl 16(4S): S9.
  10. Pietropolli, A., Vicario, R., Peconi, C., Zampatti, S., Quitadamo, M. C., Capogna, M. V., Ragazzo, M., Nardone, A. M., Postorivo, D., Spitalieri, P., Sarta, S., Ratto, F., Novelli, G., Sangiuolo, F., Piccione, E. and Giardina, E. (2014). Transabdominal coelocentesis as early source of fetal DNA for chromosomal and molecular diagnosis. J Matern Fetal Neonatal Med 27(16): 1656-1660.
  11. Spitalieri, P., Quitadamo, M. C., Orlandi, A., Puxeddu, E., Curradi, G. and Sangiuolo, F. (2013). Human embryonic stem cells recover in vivo acute lung inflammation bleomycin-induced. Sarcoidosis Vasc Diffuse Lung Dis 30(3): 177-185.
  12. Spitalieri, P., Quitadamo, M. C., Orlandi, A., Guerra, L., Giardina, E., Casavola, V., Novelli, G., Saltini, C. and Sangiuolo, F. (2012). Rescue of murine silica-induced lung injury and fibrosis by human embryonic stem cells. Eur Respir J 39(2): 446-457.
  13. Spitalieri, P., Quitadamo, M. C., Orlandi, A., Guerra, L., Giardina, E., Casavola, V., Saltini, C. and Sangiuolo, F. (2011). Human embryonic stem cells ability to recover a silica lung injury model. EMBO, Advances in stem cell research p: 179.
  14. Spitalieri, P., Quitadamo, M. C., Sangiuolo, F. and Epithelium, L. (2011). Regenerative Medicine: Current and Potential Applications. In: Barrisi, A. (Ed.). Biothecnology in Surgery 5.4: 84-86.
  15. Malgieri, A., Spitalieri, P., Novelli, G., Sangiuolo, F. and Therapy, G. (2011). Regenerative Medicine: Current and Potential Applications. In: Barrisi, A. (Ed.). Biothecnology in Surgery 5.4: 115-119.
  16. Malgieri, A., Luchetti, A., Sanchez, M., Bellocchi, M., Spitalieri, P. and Murdocca, M., Novelli, G. and Sangiuolo, F. (2010). Restored SMN1 expression by lentiviral vector in mES cellsderived from SMA1 mice. XVIII Annual Congress of the European Society of Gene and Cell Therapy p: 322.
  17. Spitalieri, P., Quitadamo, M. C., Orlandi, A., Guerra, L., Giardina, E., Casavola, V., Novelli, G. and Sangiuolo, F. (2010). Engraftment capacity of human embryonic stem cells into bleomycin and silica lung damaged mice. XVIII Annual Congress of the European Society of Gene and Cell Therapy p: 378.
  18. Spitalieri, P., Quitadamo, M. C., Orlandi, A., Guerra, L., Giardina, E., Bernardini, L., Lazzari, G., Novelli, G. and Sangiuolo, F. (2010). Engraftment capacity of hes-derivedalveolar type II pneumocytes intosilica and bleomycin lung-damaged mice. International Society for Stem Cell Research 8th Annual Meeting C 53.
  19. Sangiuolo, F. and Spitalieri, P. (2009). Alveolar epithelial type II pneumocytes from human embryonic stem cell. International Society for Stem Cell Research 7th Annual Meeting P465.
  20. Spitalieri, P., Cortese, G., Pietropolli, A., Filareto, A., Dolci, S., Klinger, F. G., Giardina, E., Di Cesare, S., Bernardini, L., Lauro, D., Scaldaferri, H. L., Citro, G., Novelli, G., De Felici, M. and Sangiuolo, F. (2009). Identification of multipotent cytotrophoblast cells from human first trimester chorionic villi. Cloning Stem Cells 11(4): 535-56.
  21. Sangiuolo, F., Scaldaferri, M. L., Filareto, A., Spitalieri, P., Guerra, L., Favia, M., Caroppo, R., Mango, R., Bruscia, E., Gruenert, D. C., Casavola, V., De Felici, M. and Novelli, G. (2008). Cftr gene targeting in mouse embryonic stem cells mediated by Small Fragment Homologous Replacement (SFHR). Front Biosci 13: 2989-2999.
  22. Filareto, A., Ferraguti, G., Malgieri, A., Luchetti, A., Spitalieri, P., Strom, R., Novelli, G., Sangiuolo, F. and Lucarelli, M. (2008). DNA methilation enhances repair efficiency of small fragment homologous replacement (SFHR) gene targeting. American Socity of Gene Therapy 11th meeting  S15.
  23. Filareto, A., Malgieri, A., Luchetti, A., Spitalieri, P., Moore, S., Fina, D., Kerr, D. A., Novelli, G., Sangiuolo, F. (2008). Recovery of full lenght SMN protein by a gene targeting approach (Small Fragment Homologous Replacement) in murine ES cells derived from SMA I mice. American Society of Gene Therapy 11th Annual Meeting; Molecular Therapy 18: S349-350.
  24. Spitalieri, P., Favia, M., Quitadamo, M. C., Cortese, G., Malgieri, A., Luchetti, A., Citro, G., Baldi, A., Lazzari, G., Guerra, L., Casavola, V., Novelli, G. and Sangiuolo, F. (2008). Differentation of human embryonic stem cells into alveolar epithelial type II pneumocytes. XVI Annual Congress of the European Society of Gene  and Cell Therapy; Human Gene Therapy 19(10): 1181,P 223.
1 Protocol published
GC/MS-based Analysis of Volatile Metabolic Profile Along in vitro Differentiation of Human Induced Pluripotent Stem Cells
Human induced pluripotent stem cells (hiPSCs) are a promising tool in cell-based therapies for degenerative diseases. A safe application of hiPSCs in vivo, requires the detection of the presence of residual undifferentiated pluripotent ...
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