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Coauthors
Cláudia Guimas Almeida CEDOC–Chronic Diseases Research Centre, NOVA Medical School|Faculdade de Ciências Médicas–Universidade NOVA de Lisboa, Portugal, Portugal,
2 protocols

Tatiana Burrinha CEDOC–Chronic Diseases Research Centre, NOVA Medical School|Faculdade de Ciências Médicas–Universidade NOVA de Lisboa, Portugal, Portugal,
2 protocols

Florent Ubelmann
  • CEDOC, Chronic Diseases Research Centre, Universidade NOVA de Lisboa / NOVA Medical School|Faculdade de Ciências Médicas, Portugal, Portugal,
  • 2 Author merit

Education

PhD, Universite Pierre et Marie Curie, France, 2013

Current position

Analyst, corporate development, onxeo, France

Publications

  1. Ubelmann, F., Burrinha, T., Salavessa, L., Gomes, R., Ferreira, C., Moreno, N. and Guimas Almeida, C. (2017). Bin1 and CD2AP polarise the endocytic generation of beta-amyloid. EMBO Rep 18(1): 102-122.
  2. Lhocine, N., Arena, E. T., Bomme, P., Ubelmann, F., Prevost, M. C., Robine, S. and Sansonetti, P. J. (2015). Apical invasion of intestinal epithelial cells by Salmonella typhimurium requires villin to remodel the brush border actin cytoskeleton. Cell Host Microbe 17(2): 164-177.
  3. Ubelmann, F., Chamaillard, M., El-Marjou, F., Simon, A., Netter, J., Vignjevic, D., Nichols, B. L., Quezada-Calvillo, R., Grandjean, T., Louvard, D., Revenu, C. and Robine, S. (2013). Enterocyte loss of polarity and gut wound healing rely upon the F-actin-severing function of villin. Proc Natl Acad Sci U S A 110(15): E1380-1389.
  4. Revenu, C., Ubelmann, F., Hurbain, I., El-Marjou, F., Dingli, F., Loew, D., Delacour, D., Gilet, J., Brot-Laroche, E., Rivero, F., Louvard, D. and Robine, S. (2012). A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins. Mol Biol Cell 23(2): 324-336.
  5. Boulant, S., Kural, C., Zeeh, J. C., Ubelmann, F. and Kirchhausen, T. (2011). Actin dynamics counteract membrane tension during clathrin-mediated endocytosis. Nat Cell Biol 13(9): 1124-1131.
2 Protocols published
Measuring the Endocytic Recycling of Amyloid Precursor Protein (APP) in Neuro2a Cells
Authors:  Florent Ubelmann, Tatiana Burrinha and Claudia Guimas Almeida, date: 12/05/2017, view: 1449, Q&A: 0
The established primary trigger of Alzheimer’s disease’s is β-amyloid (Aβ) (Mucke and Selkoe, 2012). Amyloid precursor protein (APP) endocytosis is required for Aβ generation at early endosomes (Rajendran and Annaert, 2012). APP retention at ...
A Novel Protocol to Quantitatively Measure the Endocytic Trafficking of Amyloid Precursor Protein (APP) in Polarized Primary Neurons with Sub-cellular Resolution
Authors:  Florent Ubelmann, Tatiana Burrinha and Cláudia Guimas Almeida, date: 12/05/2017, view: 1440, Q&A: 0
Alzheimer’s disease’s established primary trigger is β-amyloid (Aβ) (Mucke and Selkoe, 2012). The amyloid precursor protein (APP) endocytosis is required for Aβ generation at early endosomes (Rajendran and Annaert, 2012). APP retention at endosomes ...