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Reviewer
takashi nishina
  • Research scientist, Toho University
Research focus
  • Biochemistry
  • Mucosal Immunology
    Oxidative Stress
    Gastroenterology
    Cancer Biology
    Signal Transduction Pathway

Education

Ph.D., University of Tokyo, 2010

Publications

https://scholar.google.co.jp/citations?user=SucI6LgAAAAJ&hl=ja

1: Nishina T, Deguchi Y, Miura R, Yamazaki S, Shinkai Y, Kojima Y, Okumura K,
Kumagai Y, Nakano H. Critical Contribution of Nuclear Factor Erythroid 2-related
Factor 2 (NRF2) to Electrophile-induced Interleukin-11 Production. J Biol Chem.
2017 Jan 6;292(1):205-216. doi: 10.1074/jbc.M116.744755. Epub 2016 Nov 21. PubMed
PMID: 27872193; PubMed Central PMCID: PMC5217680.


2: Sakata K, Araki K, Nakano H, Nishina T, Komazawa-Sakon S, Murai S, Lee GE,
Hashimoto D, Suzuki C, Uchiyama Y, Notohara K, Gukovskaya AS, Gukovsky I,
Yamamura KI, Baba H, Ohmuraya M. Novel method to rescue a lethal phenotype
through integration of target gene onto the X-chromosome. Sci Rep. 2016 Nov
15;6:37200. doi: 10.1038/srep37200. PubMed PMID: 27845447; PubMed Central PMCID:
PMC5109027.


3: Piao X, Komazawa-Sakon S, Nishina T, Koike M, Piao JH, Ehlken H, Kurihara H,
Hara M, Van Rooijen N, Schütz G, Ohmuraya M, Uchiyama Y, Yagita H, Okumura K, He
YW, Nakano H. c-FLIP maintains tissue homeostasis by preventing apoptosis and
programmed necrosis. Sci Signal. 2012 Dec 18;5(255):ra93. doi:
10.1126/scisignal.2003558. PubMed PMID: 23250397; PubMed Central PMCID:
PMC4465294.


4: Nishina T, Komazawa-Sakon S, Yanaka S, Piao X, Zheng DM, Piao JH, Kojima Y,
Yamashina S, Sano E, Putoczki T, Doi T, Ueno T, Ezaki J, Ushio H, Ernst M,
Tsumoto K, Okumura K, Nakano H. Interleukin-11 links oxidative stress and
compensatory proliferation. Sci Signal. 2012 Jan 17;5(207):ra5. doi:
10.1126/scisignal.2002056. PubMed PMID: 22253262.


5: Kojima Y, Nakayama M, Nishina T, Nakano H, Koyanagi M, Takeda K, Okumura K,
Yagita H. Importin β1 protein-mediated nuclear localization of death receptor 5
(DR5) limits DR5/tumor necrosis factor (TNF)-related apoptosis-inducing ligand
(TRAIL)-induced cell death of human tumor cells. J Biol Chem. 2011 Dec
16;286(50):43383-93. doi: 10.1074/jbc.M111.309377. Epub 2011 Oct 21. PubMed PMID:
22020938; PubMed Central PMCID: PMC3234854.


6: Nishina T, Yamaguchi N, Gohda J, Semba K, Inoue J. NIK is involved in
constitutive activation of the alternative NF-kappaB pathway and proliferation of
pancreatic cancer cells. Biochem Biophys Res Commun. 2009 Oct 9;388(1):96-101.
doi: 10.1016/j.bbrc.2009.07.125. Epub 2009 Jul 29. PubMed PMID: 19646419.