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David Sanz
Physiology, University College Cork, Ireland
1 protocol
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Patrick T. Harrison
Department of Physiology, BioSciences Institute, University College Cork, Cork, Ireland
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1 Protocol published
Minigene Assay to Evaluate CRISPR/Cas9-based Excision of Intronic Mutations that Cause Aberrant Splicing in Human Cells
Authors:
David J. Sanz
and
Patrick T. Harrison
,
date:
06/05/2019,
view:
2958,
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The construction of Hybrid minigenes provides a robust and simple strategy to study the effects of disease-causing mutations on mRNA splicing when biological material from patient cells is not available. Hybrid minigenes can be used as splicing ...
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