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Erwin Van Meir
School of Medicine and Winship Cancer Institute, USA
2 protocols
Shannon Rivera
Department of Chemistry, Emory University, USA
1 protocol
Anil Mehta
Department of Chemistry, Emory University, USA
1 protocol
Stefan Kaluz
Laboratory of Molecular Neuro-Oncology, Departments of Neurosurgery and Hematology & Medical Oncology, School of Medicine and Winship Cancer Institute, Emory University, USA
1 protocol
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Emily Weinert
Department of Chemistry, Emory University, USA
Research focus
Cancer biology
Contributions
1
Author merit
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1 Protocol published
Purifying Properly Folded Cysteine-rich, Zinc Finger Containing Recombinant Proteins for Structural Drug Targeting Studies: the CH1 Domain of p300 as a Case Example
Authors:
Yong Joon Kim
,
Stefan Kaluz
,
Anil Mehta
,
Emily Weinert
,
Shannon Rivera
and
Erwin G. Van Meir
,
date:
09/05/2017,
view:
8354,
Q&A:
0
The transcription factor Hypoxia-Inducible Factor (HIF) complexes with the coactivator p300, activating the hypoxia response pathway and allowing tumors to grow. The CH1 and CAD domains of each respective protein form the interface between p300 and ...
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