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Coauthors
Giovanni Marsicano U1215 INSERM Neurocentre Magendie, University of Bordeaux, France
3 protocols

Guillaume Ferreira University of Bordeaux, France
1 protocol

Edgar Soria-Gomez Achucarro Basque Center for Neuroscience
2 protocols
Coreviewers
Emma Puighermanal Universitat Autònoma de Barcelona
2 protocols

Oneil Bhalala Baker Institute
41 protocols

Reviewer
Arnau Busquets-Garcia
  • NeuroCentre Magendie
Research focus
  • Neuroscience
  • 2 Author merit

Education

Ph.D in Biomedicine, University Pompeu Fabra, Spain, 2008

Current position

Postdoctoral felow, Neurocentre Magendie, INSERM U1215, France

Publications

  1. Busquets-Garcia, A., Soria-Gomez, E., Redon, B., Mackenbach, Y., Vallee, M., Chaouloff, F., Varilh, M., Ferreira, G., Piazza, P. V. and Marsicano, G. (2017). Pregnenolone blocks cannabinoid-induced acute psychotic-like states in mice. Mol Psychiatry.
  2. Saravia, R., Flores, A., Plaza-Zabala, A., Busquets-Garcia, A., Pastor, A., de la Torre, R., Di Marzo, V., Marsicano, G., Ozaita, A., Maldonado, R. and Berrendero, F. (2017). CB1 Cannabinoid Receptors Mediate Cognitive Deficits and Structural Plasticity Changes During Nicotine Withdrawal. Biol Psychiatry 81(7): 625-634.
  3. Hebert-Chatelain, E., Desprez, T., Serrat, R., Bellocchio, L., Soria-Gomez, E., Busquets-Garcia, A., Pagano Zottola, A. C., Delamarre, A., Cannich, A., Vincent, P., Varilh, M., Robin, L. M., Terral, G., Garcia-Fernandez, M. D., Colavita, M., Mazier, W., Drago, F., Puente, N., Reguero, L., Elezgarai, I., Dupuy, J. W., Cota, D., Lopez-Rodriguez, M. L., Barreda-Gomez, G., Massa, F., Grandes, P., Benard, G. and Marsicano, G. (2016). A cannabinoid link between mitochondria and memory. Nature 539(7630): 555-559.
  4. Gomis-Gonzalez, M., Busquets-Garcia, A., Matute, C., Maldonado, R., Mato, S. and Ozaita, A. (2016). Possible Therapeutic Doses of Cannabinoid Type 1 Receptor Antagonist Reverses Key Alterations in Fragile X Syndrome Mouse Model. Genes (Basel) 7(9).
  5. Ramos-Fernandez, E., Tajes, M., Ill-Raga, G., Vargas, L., Busquets-Garcia, A., Bosch-Morato, M., Guivernau, B., Valls-Comamala, V., Gomis, M., Grau, C., Fandos, C., Rosen, M. D., Rabinowitz, M. H., Inestrosa, N., Maldonado, R., Altafaj, X., Ozaita, A., Alvarez, A., Vicente, R., Valverde, M. A. and Munoz, F. J. (2016). Glutamatergic stimulation induces GluN2B translation by the nitric oxide-Heme-Regulated eIF2alpha kinase in cortical neurons. Oncotarget 7(37): 58876-58892.
  6. Busquets-Garcia, A., Gomis-Gonzalez, M., Srivastava, R. K., Cutando, L., Ortega-Alvaro, A., Ruehle, S., Remmers, F., Bindila, L., Bellocchio, L., Marsicano, G., Lutz, B., Maldonado, R. and Ozaita, A. (2016). Peripheral and central CB1 cannabinoid receptors control stress-induced impairment of memory consolidation. Proc Natl Acad Sci U S A 113(35): 9904-9909.
  7. Busquets Garcia, A., Soria-Gomez, E., Bellocchio, L. and Marsicano, G. (2016). Cannabinoid receptor type-1: breaking the dogmas. F1000Res 5.
  8. Busquets-Garcia, A., Desprez, T., Metna-Laurent, M., Bellocchio, L., Marsicano, G. and Soria-Gomez, E. (2015). Dissecting the cannabinergic control of behavior: The where matters. Bioessays 37(11): 1215-1225.
  9. Soria-Gomez, E., Busquets-Garcia, A., Hu, F., Mehidi, A., Cannich, A., Roux, L., Louit, I., Alonso, L., Wiesner, T., Georges, F., Verrier, D., Vincent, P., Ferreira, G., Luo, M. and Marsicano, G. (2015). Habenular CB1 Receptors Control the Expression of Aversive Memories. Neuron 88(2): 306-313.
  10. Ill-Raga, G., Tajes, M., Busquets-Garcia, A., Ramos-Fernandez, E., Vargas, L. M., Bosch-Morato, M., Guivernau, B., Valls-Comamala, V., Eraso-Pichot, A., Guix, F. X., Fandos, C., Rosen, M. D., Rabinowitz, M. H., Maldonado, R., Alvarez, A. R., Ozaita, A. and Munoz, F. J. (2015). Physiological Control of Nitric Oxide in Neuronal BACE1 Translation by Heme-Regulated eIF2alpha Kinase HRI Induces Synaptogenesis. Antioxid Redox Signal 22(15): 1295-1307.
  11. Busquets-Garcia, A., Maldonado, R. and Ozaita, A. (2014). New insights into the molecular pathophysiology of fragile X syndrome and therapeutic perspectives from the animal model. Int J Biochem Cell Biol 53: 121-126.
  12. Busquets-Garcia, A., Gomis-Gonzalez, M., Guegan, T., Agustin-Pavon, C., Pastor, A., Mato, S., Perez-Samartin, A., Matute, C., de la Torre, R., Dierssen, M., Maldonado, R. and Ozaita, A. (2013). Targeting the endocannabinoid system in the treatment of fragile X syndrome. Nat Med 19(5): 603-607.
  13. Garcia-Gutierrez, M. S., Ortega-Alvaro, A., Busquets-Garcia, A., Perez-Ortiz, J. M., Caltana, L., Ricatti, M. J., Brusco, A., Maldonado, R. and Manzanares, J. (2013). Synaptic plasticity alterations associated with memory impairment induced by deletion of CB2 cannabinoid receptors. Neuropharmacology 73: 388-396.
  14. Cutando, L., Busquets-Garcia, A., Puighermanal, E., Gomis-Gonzalez, M., Delgado-Garcia, J. M., Gruart, A., Maldonado, R. and Ozaita, A. (2013). Microglial activation underlies cerebellar deficits produced by repeated cannabis exposure. J Clin Invest 123(7): 2816-2831.
  15. Puighermanal, E., Busquets-Garcia, A., Gomis-Gonzalez, M., Marsicano, G., Maldonado, R. and Ozaita, A. (2013). Dissociation of the pharmacological effects of THC by mTOR blockade. Neuropsychopharmacology 38(7): 1334-1343.
  16. Puighermanal, E., Busquets-Garcia, A., Maldonado, R. and Ozaita, A. (2012). Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids. Philos Trans R Soc Lond B Biol Sci 367(1607): 3254-3263.
  17. Busquets-Garcia, A., Puighermanal, E., Pastor, A., de la Torre, R., Maldonado, R. and Ozaita, A. (2011). Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses. Biol Psychiatry 70(5): 479-486.
  18. Puighermanal, E., Marsicano, G., Busquets-Garcia, A., Lutz, B., Maldonado, R. and Ozaita, A. (2009). Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling. Nat Neurosci 12(9): 1152-1158.
  19. Comas, D., Schmid, H., Braeuer, S., Flaiz, C., Busquets, A., Calafell, F., Bertranpetit, J., Scheil, H. G., Huckenbeck, W., Efremovska, L. and Schmidt, H. (2004). Alu insertion polymorphisms in the Balkans and the origins of the Aromuns. Ann Hum Genet 68(Pt 2): 120-127.
2 Protocols published
Assessing Prepulse Inhibition of Startle in Mice
Authors:  Christina Ioannidou, Giovanni Marsicano and Arnau Busquets-Garcia, date: 04/05/2018, view: 290, Q&A: 0
Animal models are an important tool for studying neuropsychiatric disorders. However, a major challenge for researchers working with laboratory rodents is trying to reproduce ‘core’ symptoms of complex human disorders such as schizophrenia. Despite ...
Representation-mediated Aversion as a Model to Study Psychotic-like States in Mice
Authors:  Arnau Busquets-Garcia, Edgar Soria-Gómez, Guillaume Ferreira and Giovanni Marsicano, date: 06/20/2017, view: 1616, Q&A: 0
Several paradigms for rodent models of the cognitive and negative endophenotypes found in schizophrenic patients have been proposed. However, significant efforts are needed in order to study the pathophysiology of schizophrenia-related positive ...
1 Protocol reviewed
Barnes Maze Procedure for Spatial Learning and Memory in Mice
Author:  Matthew W. Pitts, date: 03/05/2018, view: 525, Q&A: 0
The Barnes maze is a dry-land based rodent behavioral paradigm for assessing spatial learning and memory that was originally developed by its namesake, Carol Barnes. It represents a well-established alternative to the more popular Morris Water maze ...
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