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Richard Pomerantz
Fels Institute for Cancer Research, Department of Medical Genetics and Molecular Biochemistry, Temple University Lewis Katz School of Medicine, USA
1 protocol
Tatiana Kent
Fels Institute for Cancer Research, Department of Medical Genetics and Molecular Biochemistry, Temple University Lewis Katz School of Medicine, USA
1 protocol
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Trung M. Hoang
Fels Institute for Cancer Research, Department of Medical Genetics and Molecular Biochemistry, Temple University Lewis Katz School of Medicine, USA
Research focus
Molecular biology
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1 Protocol published
Modification of 3’ Terminal Ends of DNA and RNA Using DNA Polymerase θ Terminal Transferase Activity
Authors:
Trung M. Hoang
,
Tatiana Kent
and
Richard T. Pomerantz
,
date:
06/20/2017,
view:
6390,
Q&A:
0
DNA polymerase θ (Polθ) is a promiscuous enzyme that is essential for the error-prone DNA double-strand break (DSB) repair pathway called alternative end-joining (alt-EJ). During this form of DSB repair, Polθ performs terminal transferase activity ...
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