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Coauthors
Yunfei Bai 1 protocol

Dandan Cao 1 protocol

Liang Li
  • Capital Medical University
  • 1 Author merit

Education

Ph.D., Capital Medical University, China, 2005

Current position

Head, Pathology, Capital Medical University, China

Publications

  1. Fang, C., Li, Q., Min, G., Liu, M., Cui, J., Sun, J. and Li, L. (2017). MicroRNA-181c Ameliorates Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats. Mol Neurobiol 54(10): 8370-8385.
  2. Li, Q., Cui, J., Fang, C., Liu, M., Min, G. and Li, L. (2017). S-Adenosylmethionine Attenuates Oxidative Stress and Neuroinflammation Induced by Amyloid-beta Through Modulation of Glutathione Metabolism. J Alzheimers Dis 58(2): 549-558.
  3. Zhang, X., Huang, X., Fang, C., Li, Q., Cui, J., Sun, J. and Li, L. (2017). miR-124 Regulates the Expression of BACE1 in the Hippocampus Under Chronic Cerebral Hypoperfusion. Mol Neurobiol 54(4): 2498-2506.
  4. Li, Q., Cui, J., Fang, C., Zhang, X. and Li, L. (2016). S-adenosylmethionine Administration Attenuates Low Brain-Derived Neurotrophic Factor Expression Induced by Chronic Cerebrovascular Hypoperfusion or Beta Amyloid Treatment. Neurosci Bull 32(2): 153-161.
  5. Yang, Q., Wu, X., Sun, J., Cui, J. and Li, L. (2016). Epigenetic Features Induced by Ischemia-Hypoxia in Cultured Rat Astrocytes. Mol Neurobiol 53(1): 436-445.
  6. Wu, X., Sun, J., Zhang, X., Li, X., Liu, Z., Yang, Q. and Li, L. (2014). Epigenetic signature of chronic cerebral hypoperfusion and beneficial effects of S-adenosylmethionine in rats. Mol Neurobiol 50(3): 839-851.
  7. Gu, X., Sun, J., Li, S., Wu, X. and Li, L. (2013). Oxidative stress induces DNA demethylation and histone acetylation in SH-SY5Y cells: potential epigenetic mechanisms in gene transcription in Abeta production. Neurobiol Aging 34(4): 1069-1079.
  8. Wu, X., Sun, J. and Li, L. (2013). Chronic cerebrovascular hypoperfusion affects global DNA methylation and histone acetylation in rat brain. Neurosci Bull 29(6): 685-692.
  9. Liu, H., Xing, A., Wang, X., Liu, G. and Li, L. (2012). Regulation of beta-amyloid level in the brain of rats with cerebrovascular hypoperfusion. Neurobiol Aging 33(4): 826 e831-842.
  10. Guo, X., Wu, X., Ren, L., Liu, G. and Li, L. (2011). Epigenetic mechanisms of amyloid-beta production in anisomycin-treated SH-SY5Y cells. Neuroscience 194: 272-281.
1 Protocol published
Common Carotid Arteries Occlusion Surgery in Adult Rats as a Model of Chronic Cerebral Hypoperfusion
Authors:  Dandan Cao, Yunfei Bai and Liang Li, date: 01/20/2018, view: 1418, Q&A: 0
Chronic cerebral hypoperfusion (CCH) is an important risk factor of vascular dementia (VaD) and Alzheimer’s disease (AD). Hypoxia/ischemia in the whole brain induced by CCH causes serious damage to brain structure and function, which can lead to ...