Melanie Ott Gladstone Institute for Virology and Immunology, The University of California San Francisco, USA
3 protocols
Alessandro Didonna University of California, San Francisco
27 protocols

Marielle Cavrois Gladstone Institutes and University of California, San Francisco
7 protocols

Pooja Saxena Medicago R&D Inc.
7 protocols

Vaibhav Shah The University of New South Wales
16 protocols

Reviewer
Daniela Boehm
  • Gladstone Institute of Virology and Immunology
Research focus
  • Molecular biology
  • 2 Author merit
2 Protocols published
Flow Cytometric Analysis of HIV-1 Transcriptional Activity in Response to shRNA Knockdown in A2 and A72 J-Lat Cell Lines
Authors:  Daniela Boehm and Melanie Ott, date: 06/05/2017, view: 4946, Q&A: 0
The main obstacle to eradicating HIV-1 from patients is post-integration latency (Finzi et al., 1999). Antiretroviral treatments target only actively replicating virus, while latent infections that have low or no transcriptional activity ...
Flow Cytometric Analysis of Drug-induced HIV-1 Transcriptional Activity in A2 and A72 J-Lat Cell Lines
Authors:  Daniela Boehm and Melanie Ott, date: 05/20/2017, view: 6416, Q&A: 0
The main obstacle to eradicating HIV-1 from patients is post-integration latency (Finzi et al., 1999). Antiretroviral treatments target only actively replicating virus, while latent infections that have low or no transcriptional activity ...
3 Protocols reviewed
A Mismatch-tolerant RT-LAMP Method for Molecular Diagnosis of Highly Variable Viruses
Authors:  Yingxue Li, Yi Zhou, Yingying Ma, Rong Xu, Xia Jin and Chiyu Zhang, date: 11/05/2019, view: 150, Q&A: 0
Loop-mediated isothermal amplification (LAMP) has been widely used in the detection of pathogens. However, there are usually numerous variants in one viral pathogen and primers employed in LAMP can hardly match all these variants. The mismatches ...
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Viral Chromosome Conformation Capture (V3C) Assays for Identifying Trans-interaction Sites between Lytic Viruses and the Cellular Genome
Authors:  Kinjal Majumder, Maria Boftsi and David J Pintel, date: 03/20/2019, view: 1125, Q&A: 0
The folding mechanisms of the mammalian genome package our genetic material into the nucleus, and in doing so, dictate its appropriate replication and expression. Chromosome conformation capture technology has enabled the dissection of the folding ...
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