Holger Bierhoff Department of Biochemistry, Institute of Biochemistry and Biophysics, Center for Molecular Biomedicine (CMB), Friedrich Schiller University Jena, Germany
1 protocol

Zhongliang Zhao
  • Division of Molecular Biology of the Cell II, German Cancer Research Center, DKFZ-ZMBH Alliance, Im Neuenheimer Feld 581, Germany
  • 1 Author merit


Ph.D, PUMC, China, 2011

Current position

Postdoc, Molecular Biology of the Cell II , German Cancer Research Center,dkfz, Germany


  1. Zhao, Z., Dammert, M. A., Hoppe, S., Bierhoff, H. and Grummt, I. (2016). Heat shock represses rRNA synthesis by inactivation of TIF-IA and lncRNA-dependent changes in nucleosome positioning. Nucleic Acids Res 44(17): 8144-8152.
  2. Zhao, Z., Dammert, M. A., Grummt, I. and Bierhoff, H. (2016). lncRNA-Induced Nucleosome Repositioning Reinforces Transcriptional Repression of rRNA Genes upon Hypotonic Stress. Cell Rep 14(8): 1876-1882.
1 Protocol published
Nucleosome Positioning Assay
Authors:  Zhongliang Zhao and Holger Bierhoff, date: 05/20/2017, view: 3894, Q&A: 0
The basic unit of chromatin is the nucleosome, a histone octamer with 147 base pairs of DNA wrapped around it. Positions of nucleosomes relative to each other and to DNA elements have a strong impact on chromatin structure and gene activity and are ...