Shihuan Kuang Department of Animal Science, Purdue University, USA
3 protocols

Feng Yue Department of Animal Science, Purdue University, USA
1 protocol

Chao Wang
  • Purdue University
Research focus
  • Stem cell
  • 1 Author merit


Ph.D, Purdue University, USA, 2017

Current position

Research Assistant, Animal Science, Purdue University, USA


  1. Wang, C., Liu, W., Nie, Y., Qaher, M., Horton, H. E., Yue, F., Asakura, A. and Kuang, S. (2017). Loss of MyoD Promotes Fate Transdifferentiation of Myoblasts Into Brown Adipocytes. EBioMedicine 16: 212-223.
  2. Wang, C., Wang, M., Arrington, J., Shan, T., Yue, F., Nie, Y., Tao, W. A. and Kuang, S. (2017). Ascl2 inhibits myogenesis by antagonizing the transcriptional activity of myogenic regulatory factors. Development 144(2): 235-247.
  3. Yang, X., Yang, S., Wang, C. and Kuang, S. (2017). The hypoxia-inducible factors HIF1alpha and HIF2alpha are dispensable for embryonic muscle development but essential for postnatal muscle regeneration. J Biol Chem 292(14): 5981-5991.
  4. Yue, F., Bi, P., Wang, C., Shan, T., Nie, Y., Ratliff, T. L., Gavin, T. P. and Kuang, S. (2017). Pten is necessary for the quiescence and maintenance of adult muscle stem cells. Nat Commun 8: 14328.
  5. Yue, F., Bi, P., Wang, C., Li, J., Liu, X. and Kuang, S. (2016). Conditional Loss of Pten in Myogenic Progenitors Leads to Postnatal Skeletal Muscle Hypertrophy but Age-Dependent Exhaustion of Satellite Cells. Cell Rep 17(9): 2340-2353.
  6. Bi, P., Yue, F., Karki, A., Castro, B., Wirbisky, S. E., Wang, C., Durkes, A., Elzey, B. D., Andrisani, O. M., Bidwell, C. A., Freeman, J. L., Konieczny, S. F. and Kuang, S. (2016). Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice. J Exp Med 213(10): 2019-2037.
  7. Nie, Y., Sato, Y., Wang, C., Yue, F., Kuang, S. and Gavin, T. P. (2016). Impaired exercise tolerance, mitochondrial biogenesis, and muscle fiber maintenance in miR-133a-deficient mice. FASEB J 30(11): 3745-3758.
  8. Wu, Z., Hu, X., Mao, F., Wang, C., Zhang, B., Zhuang, F., Hu, K., Sun, X., Liu, X., Kuang, S. and Jin, W. (2016). Construction of a Fndc5 knockout mouse model by TALEN-mediated DNA targeting. Chinese Journal of Comparative Medicine 26(6): 37-41.
  9. Li, Z., Wang, C., Jiang, F., Huan, P. and Liu, B. (2016). Characterization and expression of a novel caspase gene: Evidence of the expansion of caspases in Crassostrea gigas. Comp Biochem Physiol B Biochem Mol Biol 201: 37-45.
  10. Wang, C., Liu, W., Liu, Z., Chen, L., Liu, X. and Kuang, S. (2015). Hypoxia Inhibits Myogenic Differentiation through p53 Protein-dependent Induction of Bhlhe40 Protein. J Biol Chem 290(50): 29707-29716.
  11. Wang, J. H., Wang, Q. J., Wang, C., Reinholt, B., Grant, A. L., Gerrard, D. E. and Kuang, S. (2015). Heterogeneous activation of a slow myosin gene in proliferating myoblasts and differentiated single myofibers. Dev Biol 402(1): 72-80.
  12. Lu, X., Wang, C. and Liu, B. (2015). The role of Cu/Zn-SOD and Mn-SOD in the immune response to oxidative stress and pathogen challenge in the clam Meretrix meretrix. Fish Shellfish Immunol 42(1): 58-65.
  13. Wang, C., Chai, X., Wang, H., Tang, B. and Liu, B. (2013). Growth performance of the clam, Meretrix meretrix, breeding-selection populations cultured in different conditions. Acta Oceanologica Sinica -English Edition 32(10): 82-87.
  14. Wang, C., Yue, X., Lu, X. and Liu, B. (2013). The role of catalase in the immune response to oxidative stress and pathogen challenge in the clam Meretrix meretrix. Fish Shellfish Immunol 34(1): 91-99.
  15. Yue, X., Wang, H., Huang, X., Wang, C., Chai, X., Wang, C. and Liu, B. (2012). Single nucleotide polymorphisms in i-type lysozyme gene and their correlation with vibrio-resistance and growth of clam Meretrix meretrix based on the selected resistance stocks. Fish Shellfish Immunol 33(3): 559-568.
  16. Wang, C., Wang, H., Li, Y. and Liu, B. (2012). Identification of a fructose-1,6-bisphosphate aldolase gene and association of the single nucleotide polymorphisms with growth traits in the clam Meretrix meretrix. Mol Biol Rep 39(4): 5017-5024.
  17. Wang, C., You, Y., Wang, H. and Liu, B. (2012). Genetic diversity of the sulfotransferase-like gene and one nonsynonymous SNP associated with growth traits of clam, Meretrix meretrix. Mol Biol Rep 39(2): 1323-1331.
  18. Wang, C., Huan, P., Yue, X., Yan, M. and Liu, B. (2011). Molecular characterization of a glutathione peroxidase gene and its expression in the selected Vibrio-resistant population of the clam Meretrix meretrix. Fish Shellfish Immunol 30(6): 1294-1302.
1 Protocol published
Muscle Histology Characterization Using H&E Staining and Muscle Fiber Type Classification Using Immunofluorescence Staining
Authors:  Chao Wang, Feng Yue and Shihuan Kuang, date: 05/20/2017, view: 4387, Q&A: 0
Muscle function is determined by its structure and fiber type composition. Here we describe a protocol to examine muscle histology and myofiber types using hematoxylin and eosin (H&E) and immunofluorescence staining, respectively. H&E stain nucleus ...
1 Protocol reviewed
Measurement of Mesenchymal Stem Cells Attachment to Endothelial Cells
Authors:  Shan Wang, Chris D. Madsen and Yaojiong Wu, date: 03/20/2018, view: 535, Q&A: 0
Mesenchymal stem cells (MSCs) have shown profound therapeutic potential in tissue repair and regeneration. However, recent studies indicate that MSCs are largely entrapped in lungs after intravenous delivery and die shortly. The underlying ...
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