Alka Mehra Institute of Genomics and Integrative Biology
33 protocols

Andrea Puhar The Laboratory for Molecular Infection Medicine Sweden (MIMS); Umeå Centre for Microbial Research (UCMR); Department of Molecular Biology, Umea University, Sweden
46 protocols

Fanny Ehret German Center for Neurodegenerative Diseases Dresden
4 protocols

Gal Haimovich Molecular Genetics, Weizmann Institute of Science, Israel
87 protocols

Reviewer
Alexandros C Kokotos
  • Post-Doc, Weill Cornell Medicine
Research focus
  • Neuroscience
  • Synaptic vesicle recycling
    Endocytosis
    Neurotransmission
    Rab GTPases
    Synaptic endosomes
    Synaptic metabolism
    GLUT4 trafficking

Education

PhD, University of Edinburgh, 2017

Lab information

Prof. Timothy Ryan's lab
https://sites.google.com/site/ryanlab1/Home

Publications

https://www.ncbi.nlm.nih.gov/pubmed/?term=kokotos+ac
Kokotos, A.C., Harper, C.B., Marland, J.R.K., Smillie, K.J., Cousin, M.A., and Gordon, S.L. (2019). Synaptophysin sustains presynaptic performance by preserving vesicular synaptobrevin-II levels. J. Neurochem 151, 28-37.

Kokotos, A.C., Peltier, J., Davenport, E.C., Trost, M., and Cousin, M.A. (2018). Activity dependent bulk endocytosis proteome reveals a key presynaptic role for the monomeric GTPase Rab11. Proceedings of the National Academy of Sciences, 201809189.

Peiris, H., Duffield, M.D., Fadista, J., Jessup, C.F., Kashmir, V., Genders, A.J., McGee, S.L., Martin, A.M., Saiedi, M., Morton, N., Carter, R., Cousin, M.A., Kokotos, A.C., Oskolkov, N., Volkov, P., Hough, T.A., Fisher, E.M., Tybulewicz, V.L., Busciglio, J., Coskun, P.E., Becker, A., Belichenko, P.V., Mobley, W.C., Ryan, M.T., Chan, J.Y., Laybutt, D.R., Coates, P.T., Yang, S., Ling, C., Groop, L., Pritchard, M.A., and Keating, D.J. (2016). A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to beta-Cell Mitochondrial Dysfunction in Type 2 Diabetes. PLoS genetics 12, e1006033.

Nicholson-Fish, J.C., Kokotos, A.C., Gillingwater, T.H., Smillie, K.J., and Cousin, M.A. (2015). VAMP4 Is an Essential Cargo Molecule for Activity-Dependent Bulk Endocytosis. Neuron 88, 973-984.

Kokotos, A.C., and Low, D.W. (2015). Myosin II and Dynamin Control Actin Rings to Mediate Fission during Activity-Dependent Bulk Endocytosis. The Journal of neuroscience 35, 8687-8688.

Kokotos, A.C., and Cousin, M.A. (2015). Synaptic vesicle generation from central nerve terminal endosomes. Traffic 16, 229-240.

Karachaliou, M., Amillis, S., Evangelinos, M., Kokotos, A.C., Yalelis, V., and Diallinas, G. (2013). The arrestin-like protein ArtA is essential for ubiquitination and endocytosis of the UapA transporter in response to both broad-range and specific signals. Molecular microbiology 88, 301-317.
11 Protocols reviewed
Preparation of Teased Nerve Fibers from Rat Sciatic Nerve
Authors:  Jinkun Wen, Lixia Li, Dandan Tan and Jiasong Guo, date: 10/05/2017, view: 5983, Q&A: 0
Compared to tissue sectioning techniques, the technique of teasing single nerve fibers provides a better way to understand the structures of myelin sheaths and axons of the peripheral myelinated nerves. This protocol describes a method for ...
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Ciberial Muscle 9 (CM9) Electrophysiological Recordings in Adult Drosophila melanogaster
Authors:  Benjamin A. Eaton and Rebekah E. Mahoney, date: 07/20/2017, view: 3901, Q&A: 0
The complexity surrounding presynaptic recordings in mammals is a significant barrier to the study of presynaptic mechanisms during neurotransmission in the mammalian central nervous system (CNS). Here we describe an adult fly neuromuscular junction ...
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