Akira Karasawa New York Structural Biology Center
8 protocols

Alka Mehra Institute of Genomics and Integrative Biology
40 protocols

Andrea Puhar MIMS and Department of Molecular Biology, Umeå University
53 protocols

Carmelo Bellardita Neuroscience Department, University of Copenhagen , Denmark, Denmark,
2 protocols

Reviewer
Alexandros C Kokotos
  • Post-Doc, Weill Cornell Medicine
Research focus
  • Neuroscience
  • Synaptic vesicle recycling
    Endocytosis
    Neurotransmission
    Rab GTPases
    Synaptic endosomes
    Synaptic metabolism
    GLUT4 trafficking

Education

PhD, University of Edinburgh, 2017

Lab information

Prof. Timothy Ryan's lab
https://sites.google.com/site/ryanlab1/Home

Publications

https://www.ncbi.nlm.nih.gov/pubmed/?term=kokotos+ac
Kokotos, A.C., Harper, C.B., Marland, J.R.K., Smillie, K.J., Cousin, M.A., and Gordon, S.L. (2019). Synaptophysin sustains presynaptic performance by preserving vesicular synaptobrevin-II levels. J. Neurochem 151, 28-37.

Kokotos, A.C., Peltier, J., Davenport, E.C., Trost, M., and Cousin, M.A. (2018). Activity dependent bulk endocytosis proteome reveals a key presynaptic role for the monomeric GTPase Rab11. Proceedings of the National Academy of Sciences, 201809189.

Peiris, H., Duffield, M.D., Fadista, J., Jessup, C.F., Kashmir, V., Genders, A.J., McGee, S.L., Martin, A.M., Saiedi, M., Morton, N., Carter, R., Cousin, M.A., Kokotos, A.C., Oskolkov, N., Volkov, P., Hough, T.A., Fisher, E.M., Tybulewicz, V.L., Busciglio, J., Coskun, P.E., Becker, A., Belichenko, P.V., Mobley, W.C., Ryan, M.T., Chan, J.Y., Laybutt, D.R., Coates, P.T., Yang, S., Ling, C., Groop, L., Pritchard, M.A., and Keating, D.J. (2016). A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to beta-Cell Mitochondrial Dysfunction in Type 2 Diabetes. PLoS genetics 12, e1006033.

Nicholson-Fish, J.C., Kokotos, A.C., Gillingwater, T.H., Smillie, K.J., and Cousin, M.A. (2015). VAMP4 Is an Essential Cargo Molecule for Activity-Dependent Bulk Endocytosis. Neuron 88, 973-984.

Kokotos, A.C., and Low, D.W. (2015). Myosin II and Dynamin Control Actin Rings to Mediate Fission during Activity-Dependent Bulk Endocytosis. The Journal of neuroscience 35, 8687-8688.

Kokotos, A.C., and Cousin, M.A. (2015). Synaptic vesicle generation from central nerve terminal endosomes. Traffic 16, 229-240.

Karachaliou, M., Amillis, S., Evangelinos, M., Kokotos, A.C., Yalelis, V., and Diallinas, G. (2013). The arrestin-like protein ArtA is essential for ubiquitination and endocytosis of the UapA transporter in response to both broad-range and specific signals. Molecular microbiology 88, 301-317.
18 Protocols reviewed
Method for Rapid Enzymatic Cleaning for Reuse of Patch Clamp Pipettes: Increasing Throughput by Eliminating Manual Pipette Replacement between Patch Clamp Attempts

The whole-cell patch-clamp method is a gold standard for single-cell analysis of electrical activity, cellular morphology, and gene expression. Prior to our discovery that patch-clamp pipettes could be cleaned and reused, experimental throughput and

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In vivo Fluorescence Imaging of Extracellular ATP in the Mouse Cerebral Cortex with a Hybrid-type Optical Sensor

Adenosine 5’-triphosphate (ATP) works as an extracellular signaling molecule for cells in the brain, such as neurons and glia. Cellular communication via release of ATP is involved in a range of processes required for normal brain functions,

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