Alka Mehra Institute of Genomics and Integrative Biology
38 protocols

Andrea Puhar MIMS and Department of Molecular Biology, Umeå University
51 protocols

Fanny Ehret German Center for Neurodegenerative Diseases Dresden
4 protocols

Gal Haimovich Molecular Genetics, Weizmann Institute of Science, Israel
95 protocols

Reviewer
Alexandros C Kokotos
  • Post-Doc, Weill Cornell Medicine
Research focus
  • Neuroscience
  • Synaptic vesicle recycling
    Endocytosis
    Neurotransmission
    Rab GTPases
    Synaptic endosomes
    Synaptic metabolism
    GLUT4 trafficking

Education

PhD, University of Edinburgh, 2017

Lab information

Prof. Timothy Ryan's lab
https://sites.google.com/site/ryanlab1/Home

Publications

https://www.ncbi.nlm.nih.gov/pubmed/?term=kokotos+ac
Kokotos, A.C., Harper, C.B., Marland, J.R.K., Smillie, K.J., Cousin, M.A., and Gordon, S.L. (2019). Synaptophysin sustains presynaptic performance by preserving vesicular synaptobrevin-II levels. J. Neurochem 151, 28-37.

Kokotos, A.C., Peltier, J., Davenport, E.C., Trost, M., and Cousin, M.A. (2018). Activity dependent bulk endocytosis proteome reveals a key presynaptic role for the monomeric GTPase Rab11. Proceedings of the National Academy of Sciences, 201809189.

Peiris, H., Duffield, M.D., Fadista, J., Jessup, C.F., Kashmir, V., Genders, A.J., McGee, S.L., Martin, A.M., Saiedi, M., Morton, N., Carter, R., Cousin, M.A., Kokotos, A.C., Oskolkov, N., Volkov, P., Hough, T.A., Fisher, E.M., Tybulewicz, V.L., Busciglio, J., Coskun, P.E., Becker, A., Belichenko, P.V., Mobley, W.C., Ryan, M.T., Chan, J.Y., Laybutt, D.R., Coates, P.T., Yang, S., Ling, C., Groop, L., Pritchard, M.A., and Keating, D.J. (2016). A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to beta-Cell Mitochondrial Dysfunction in Type 2 Diabetes. PLoS genetics 12, e1006033.

Nicholson-Fish, J.C., Kokotos, A.C., Gillingwater, T.H., Smillie, K.J., and Cousin, M.A. (2015). VAMP4 Is an Essential Cargo Molecule for Activity-Dependent Bulk Endocytosis. Neuron 88, 973-984.

Kokotos, A.C., and Low, D.W. (2015). Myosin II and Dynamin Control Actin Rings to Mediate Fission during Activity-Dependent Bulk Endocytosis. The Journal of neuroscience 35, 8687-8688.

Kokotos, A.C., and Cousin, M.A. (2015). Synaptic vesicle generation from central nerve terminal endosomes. Traffic 16, 229-240.

Karachaliou, M., Amillis, S., Evangelinos, M., Kokotos, A.C., Yalelis, V., and Diallinas, G. (2013). The arrestin-like protein ArtA is essential for ubiquitination and endocytosis of the UapA transporter in response to both broad-range and specific signals. Molecular microbiology 88, 301-317.
14 Protocols reviewed
Isolation of Extracellular Vesicles Derived from Mesenchymal Stromal Cells by Ultracentrifugation
Extracellular vesicles (EVs) are a heterogeneous group of membranous vesicles that differ on their biogenesis and release pathways, such as exosomes, microvesicles and apoptotic bodies. They are involved in cell-to-cell communication delivering ...
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Isolating Multiple Extracellular Vesicles Subsets, Including Exosomes and Membrane Vesicles, from Bovine Milk Using Sodium Citrate and Differential Ultracentrifugation
Authors:  Abderrahim Benmoussa, Sara Michel, Caroline Gilbert and Patrick Provost, date: 06/05/2020, view: 1678, Q&A: 0
Milk is a complex fluid that contains various types of proteins and extracellular vesicles (EVs). Some proteins can mingle with EVs, and interfere with their isolation. Among these proteins, caseins form micelles of a size comparable to milk EVs, ...
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