Monica Colaiácovo Department of Genetics, Harvard Medical School, USA
1 protocol

Hyun-Min Kim
  • Harvard Medical School
Research focus
  • Molecular biology
  • 1 Author merit


Georgia Institute of Technology, Integrative and Systems Biology, Atlanta, USA

Current position

Post-doctoral Research Fellow, Department of Genetics, Harvard Medical School/Harvard University, Boston, USA


  1. Kim, H.* and Colaiácovo, M. P.* (2015). DNA damage sensitivity assays in Caenorhabditis elegans. Bio-protocol 5(11): e1487. (*Co-corresponding author)
  2. Kim, H.-M. and Colaiácovo, M. P. (2015). New Insights into the Post-Translational Regulation of DNA Damage Response and Double-Strand Break Repair in Caenorhabditis elegans. Genetics: genetics. 115.175661.
  3. Gao, J., Kim, H. M., Elia, A. E., Elledge, S. J. and Colaiácovo, M. P. (2015). NatB domain-containing CRA-1 antagonizes hydrolase ACER-1 linking acetyl-CoA metabolism to the initiation of recombination during C. elegans meiosis. PLoS Genet 11(3): e1005029.
  4. Kim, H. M. and Colaiácovo, M. P. (2014). ZTF-8 interacts with the 9-1-1 complex and is required for DNA damage response and double-strand break repair in the C. elegans germline. PLoS Genet 10(10): e1004723.
  5. Lu, T., Aron, L., Zullo, J., Pan, Y., Kim, H., Chen, Y., Yang, T. H., Kim, H. M., Drake, D., Liu, X. S., Bennett, D. A., Colaiácovo, M. P. and Yankner, B. A. (2014). REST and stress resistance in ageing and Alzheimer's disease. Nature 507(7493): 448-454.
  6. Saito, T. T., Lui, D. Y., Kim, H. M., Meyer, K. and Colaiácovo, M. P. (2013). Interplay between structure-specific endonucleases for crossover control during Caenorhabditis elegans meiosis. PLoS Genet 9(7): e1003586.
  7. Sengupta, M. S., Low, W. Y., Patterson, J. R., Kim, H. M., Traven, A., Beilharz, T. H., Colaiácovo, M. P., Schisa, J. A. and Boag, P. R. (2013). ifet-1 is a broad-scale translational repressor required for normal P granule formation in C. elegans. J Cell Sci 126(Pt 3): 850-859.
  8. Waisertreiger, I. S., Liston, V. G., Menezes, M. R., Kim, H. M., Lobachev, K. S., Stepchenkova, E. I., Tahirov, T. H., Rogozin, I. B. and Pavlov, Y. I. (2012). Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools. Environ Mol Mutagen 53(9): 699-724.
  9. Tang, W., Dominska, M., Greenwell, P. W., Harvanek, Z., Lobachev, K. S., Kim, H. M., Narayanan, V., Mirkin, S. M. and Petes, T. D. (2011). Friedreich's ataxia (GAA)n*(TTC)n repeats strongly stimulate mitotic crossovers in Saccharomyces cerevisae. PLoS Genet 7(1): e1001270.
  10. Kim, H. M., Narayanan, V., Mieczkowski, P. A., Petes, T. D., Krasilnikova, M. M., Mirkin, S. M. and Lobachev, K. S. (2008). Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair. EMBO J 27(21): 2896-2906.
  11. Narayanan, V., Mieczkowski, P. A., Kim, H. M., Petes, T. D. and Lobachev, K. S. (2006). The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks. Cell 125(7): 1283-1296.
  12. Kim, H. M., Ohn, T. B., Min, B. R. and Choi, Y. K. (2001). Sequence analysis and insertional inactivation of a gene encoding Moraxella sp. CK-1 cell wall hydrolase. Antonie Van Leeuwenhoek 79(2): 163-171.
1 Protocol published
DNA Damage Sensitivity Assays in Caenorhabditis elegans
Authors:  Hyun-Min Kim and Monica P. Colaiácovo, date: 06/05/2015, view: 5872, Q&A: 0
C. elegans has served as a genetically tractable multicellular model system to examine DNA damage-induced genotoxic stress which threatens genome integrity. Importantly, the high degree of conservation shared between worms and humans offers ...