Giusy Tornillo Cardiff University
4 protocols

Zhenguang Zhang 1 protocol

Gunjan Mehta
  • Post-Doc, National Institutes of Health
Research focus
  • Cell biology
  • Transcription Regulation, Single Molecule Tracking, Chromatin Remodeling, Cell Biology, Mitosis, Meiosis, Chromosome Dynamics, Kinetochore


Ph.D., Indian Institute of Technology, Bombay, India

Lab information

Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, NIH, USA


1.) Ball D*, Mehta GD*, Salomon-Kent R, Mazza D, Morisaki T, Mueller F, McNally JG, Karpova T. Single molecule tracking of Ace1p in Saccharomyces cerevisiae defines a characteristic residence time for non-specific interactions of transcription factors with chromatin. Nucleic Acids Res 2016; 44(21);e160.
* Both authors equal contribution
2.) Agarwal M, Mehta GD, Ghosh SK. Role of Ctf3 and COMA subcomplexes in meiosis: implication in maintaining Cse4 at the centromere and numeric spindle poles. Biochim Biophys Acta 2015; 1853(3);671-684.
3.) Mehta GD, Agarwal M, Ghosh SK. Functional characterization of kinetochore protein, Ctf19 in meiosis I: an implication of differential impact of Ctf19 on the assembly of mitotic and meiotic kinetochores in Saccharomyces cerevisiae. Mol. Micro 2014, 91(6):1179-1199.
4.) Mehta GD, Kumar R, Srivastava S, Ghosh SK. Cohesin: Functions beyond sister chromatid cohesion. FEBS Lett. 2013, 587(15): 2299-2312.
5.) Das A, Kapoor A, Mehta GD, Ghosh SK, Sen S. Extracellular Matrix Density Regulates Extracellular Proteolysis via Modulation of Cellular Contractility. J Carcinogene Mutagene 2013, S13:003. doi: 10.4172/2157-2518.S13-003
6.) Lahiri S, Mehta GD and Ghosh SK. Iml3p, a component of the Ctf19 complex of the budding yeast kinetochore is required to maintain kinetochore integrity under conditions of spindle stress. FEMS Yeast Res. 2013; 13(4): 375-385.
7.) Mehta GD, Rizvi SM and Ghosh SK. Cohesin: a guardian of genome integrity. Biochim Biophys Acta 2012; 1823(8): 1324-1342.
8.) Mehta GD, Agarwal M and Ghosh S. Centromere Identity: A challenge to be faced. Mol Genet Genomics 2010; 284(2): 75-94.
9.) Ray S, Mehta GD and Srivastava S. Label-free detection techniques for protein microarrays: prospects, merits and challenges. Proteomics 2010; 10: 731-748.
10.) Singh AK, Mehta GD and Chhatpar HS. Optimization of medium constituents for improved chitinase production by Paenibacillus sp. D1 using statistical approach. Letters in Applied Microbiology 2009; 49: 708-714.

2 Protocols reviewed
In vitro Explant Cultures to Interrogate Signaling Pathways that Regulate Mouse Lung Development
Authors:  Changfu Yao, Gianni Carraro and Barry R. Stripp, date: 05/20/2018, view: 28, Q&A: 0
Early mouse lung development, including specification of primordia, patterning of early endoderm and determination of regional progenitor cell fates, is tightly regulated. The ability to culture explanted embryonic lung tissue provides a tractable ...
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Functional Analysis of Connexin Channels in Cultured Cells by Neurobiotin Injection and Visualization
Authors:  Philipp Wörsdörfer and Klaus Willecke, date: 06/05/2017, view: 2137, Q&A: 0
Functional gap junction channels between neighboring cells can be assessed by microinjection of low molecular weight tracer substances into cultured cells. The extent of direct intercellular communication can be precisely quantified by this method. ...
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