Marielle Cavrois Gladstone Institutes and University of California, San Francisco
2 protocols

Warner Greene GIVI, Gladstone Institute, USA
1 protocol
HongLok Lung University of Hong Kong
57 protocols

Jyotiska Chaudhuri Buck Institute for Research on Aging
27 protocols

Shahzada Khan Gladstone Institutes
3 protocols

Tamara Vellosillo Carnegie Institution for Science
3 protocols

Jason Neidleman
  • Gladstone Institutes and University of California, San Francisco
Research focus
  • Immunology
  • 1 Author merit


B.A. in Biochemistry and Molecular Biology, University of California at Santa Barbara, 1994

Current position

Senior Research Associate in the Greene Lab, GIVI, J. David Gladstone Institutes


  1. Roan, N. R., Liu, H., Usmani, S. M., Neidleman, J., Muller, J. A., Avila-Herrera, A., Gawanbacht, A., Zirafi, O., Chu, S., Dong, M., Kumar, S. T., Smith, J. F., Pollard, K. S., Fandrich, M., Kirchhoff, F., Munch, J., Witkowska, H. E. and Greene, W. C. (2014). Liquefaction of Semen Generates and Later Degrades a Conserved Semenogelin Peptide That Enhances HIV Infection. J Virol 88(13): 7221-7234.
  2. Roan, N. R., Chu, S., Liu, H., Neidleman, J., Witkowska, H. E. and Greene, W. C. (2014). Interaction of Fibronectin With Semen Amyloids Synergistically Enhances HIV Infection. J Infect Dis.
  3. Cavrois, M., Neidleman, J., Santiago, M. L., Derdeyn, C. A., Hunter, E. and Greene, W. C. (2014). Enhanced fusion and virion incorporation for HIV-1 subtype C envelope glycoproteins with compact V1/V2 domains. J Virol 88(4): 2083-2094.
  4. Cavrois, M., Neidleman, J., Galloway, N., Derdeyn, C. A., Hunter, E. and Greene, W. C. (2011). Measuring HIV fusion mediated by envelopes from primary viral isolates. Methods 53(1): 34-38.
  5. Roan, N. R., Munch, J., Arhel, N., Mothes, W., Neidleman, J., Kobayashi, A., Smith-McCune, K., Kirchhoff, F. and Greene, W. C. (2009). The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection. J Virol 83(1): 73-80.
  6. Cavrois, M., Neidleman, J. and Greene, W. C. (2008). The achilles heel of the trojan horse model of HIV-1 trans-infection. PLoS Pathog 4(6): e1000051.
  7. Cavrois, M., Neidleman, J., Kreisberg, J. F. and Greene, W. C. (2007). In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions. PLoS Pathog 3(1): e4.
  8. Zimmerman, E. S., Sherman, M. P., Blackett, J. L., Neidleman, J. A., Kreis, C., Mundt, P., Williams, S. A., Warmerdam, M., Kahn, J., Hecht, F. M., Grant, R. M., de Noronha, C. M., Weyrich, A. S., Greene, W. C. and Planelles, V. (2006). Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. J Virol 80(21): 10407-10418.
  9. Cavrois, M., Neidleman, J., Kreisberg, J. F., Fenard, D., Callebaut, C. and Greene, W. C. (2006). Human immunodeficiency virus fusion to dendritic cells declines as cells mature. J Virol 80(4): 1992-1999.
  10. Cavrois, M., Neidleman, J., Yonemoto, W., Fenard, D. and Greene, W. C. (2004). HIV-1 virion fusion assay: uncoating not required and no effect of Nef on fusion. Virology 328(1): 36-44.
  11. Cavrois, M., Neidleman, J., Bigos, M. and Greene, W. C. (2004). Fluorescence resonance energy transfer-based HIV-1 virion fusion assay. Methods Mol Biol 263: 333-344.
  12. Bruns, K., Fossen, T., Wray, V., Henklein, P., Tessmer, U. and Schubert, U. (2003). Structural characterization of the HIV-1 Vpr N Terminus evidence of cis/trans-proline isomerism. Journal of Biological Chemistry 278(44): 43188-43201.
  13. Zander, K., Sherman, M. P., Tessmer, U., Bruns, K., Wray, V., Prechtel, A. T., Schubert, E., Henklein, P., Luban, J., Neidleman, J., Greene, W. C. and Schubert, U. (2003). Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression. J Biol Chem 278(44): 43202-43213.
  14. Sherman, M. P., de Noronha, C. M., Eckstein, L. A., Hataye, J., Mundt, P., Williams, S. A., Neidleman, J. A., Goldsmith, M. A. and Greene, W. C. (2003). Nuclear export of Vpr is required for efficient replication of human immunodeficiency virus type 1 in tissue macrophages. J Virol 77(13): 7582-7589.
  15. Vajdy, M., Gardner, J., Neidleman, J., Cuadra, L., Greer, C., Perri, S., O'Hagan, D. and Polo, J. M. (2001). Human immunodeficiency virus type 1 Gag-specific vaginal immunity and protection after local immunizations with sindbis virus-based replicon particles. J Infect Dis 184(12): 1613-1616.
  16. Neidleman, J. A., Vajdy, M., Ugozzoli, M., Ott, G. and O'Hagan, D. (2000). Genetically detoxified mutants of heat-labile enterotoxin from Escherichia coli are effective adjuvants for induction of cytotoxic T-cell responses against HIV-1 gag-p55. Immunology 101(1): 154-160.
  17. Kazzaz, J., Neidleman, J., Singh, M., Ott, G. and O'Hagan, D. T. (2000). Novel anionic microparticles are a potent adjuvant for the induction of cytotoxic T lymphocytes against recombinant p55 gag from HIV-1. J Control Release 67(2-3): 347-356.

1 Protocol published
HIV-1 Fusion Assay
Authors:  Marielle Cavrois, Jason Neidleman and Warner C. Greene, date: 08/20/2014, view: 7798, Q&A: 0
The HIV-1 fusion assay measures all steps in the HIV-1 life cycle up to and including viral fusion. It relies on the incorporation of a β-lactamase–Vpr (BlaM-Vpr) protein chimera into the virion and the subsequent transfer of this chimera into the ...
2 Protocols reviewed
Isolation of Murine Alveolar Type II Epithelial Cells
Authors:  Fan Sun, Gutian Xiao and Zhaoxia Qu, date: 05/20/2017, view: 3019, Q&A: 0
We have optimized a protocol for isolation of alveolar type II epithelial cells from mouse lung. Lung cell suspensions are prepared by intratracheal instillation of dispase and agarose followed by mechanical disaggregation of the lungs. Alveolar ...
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Gliding Assay to Analyze Microtubule-based Motor Protein Dynamics
Authors:  Albert Shim, Gin Tezuka, Luke Kupcha and Li Tao, date: 04/05/2017, view: 3647, Q&A: 0
The purpose of this protocol is to provide an updated method of performing microtubule gliding assays and visualizing it using fluorescence microscopy.
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