Jeffrey Withey Department of Immunology and Microbiology, Wayne State University School of Medicine, USA
1 protocol

Sarah C. Plecha
  • University of Toledo
Research focus
  • Microbiology
  • 1 Author merit


Ph.D. in Immunology and Microbiology, Wayne State University School of Medicine, Detroit, MI, 2014

Current position

Postdoctoral Fellow, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio (02/2015-present)


  1. Withey, J. H., Nag, D., Plecha, S. C., Sinha, R. and Koley, H. (2015). Conjugated linoleic acid reduces cholera toxin production in vitro and in vivo by inhibiting Vibrio cholerae ToxT activity. Antimicrob Agents Chemother 59(12): 7471-7476.
  2. Plecha, S. C. and Withey, J. H. (2015). Mechanism for inhibition of Vibrio cholerae ToxT activity by the unsaturated fatty acid components of bile. J Bacteriol 197(10): 1716-1725.
  3. Thomson, J. J., Plecha, S. C. and Withey, J. H. (2015). A small unstructured region in Vibrio cholerae ToxT mediates the response to positive and negative effectors and ToxT proteolysis. J Bacteriol 197(3): 654-668.
1 Protocol published
[14C] Linoleic Acid Uptake and Fractionation Assay in Vibrio cholerae
Authors:  Sarah C. Plecha and Jeffrey H. Withey, date: 12/20/2015, view: 6084, Q&A: 0
The gram-negative curved bacillus Vibrio cholerae (V. cholerae) causes the severe diarrheal illness cholera. The work presented here is to assess whether unsaturated fatty acids (UFAs), such as linoleic acid, have the potential to ...
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