Despina Smirlis Molecular Parasitology Department, Hellenic Pasteur Institute, Greece
1 protocol
Arsalan Daudi University of California
157 protocols

Begona Diaz Los Angeles Biomedical Research Institute
1 protocol

Fanglian He Bio-protocol
205 protocols

Honghong Wu University of California, Riverside
6 protocols

Editor
Alexandros Alexandratos
  • Research associate, National and Kapodistrian University of Athens
Research focus
  • Microbiology
  • Proteomics, Signaling, Transcriptomics, Gene regulation
  • 1 Author merit

Education

PhD, University of Ioannina, Greece, 2014

Lab information

Skarlatos Dedos Laboratory, Faculty of Biology, National and Kapodistrian University of Athens

Publications

Panagiotis Moulos*, Alexandros Alexandratos*, Ioannis Nellas, Skarlatos Dedos. (2018) Refining a steroidogenic model: an analysis of RNA-seq datasets from insect prothoracic glands. BMC Genomics, 19 (1): 537 (*Shared Authorship)

Alexandros Alexandratos*, Panagiotis Moulos*, Ioannis Nellas, Konstantinos Mavridis, Skarlatos Dedos. (2016) Reassessing ecdysteroidogenic cells from the cell membrane receptors’ perspective. Scientific Reports, 6, 20229 (*Shared Authorship)

Antonia Efstathiou, Nicolas Gaboriaud-Kolar, Despina Smirlis, Vassilios Myrianthopoulos, Konstantina Vougogianopoulou, Alexandros Alexandratos, Marina Kritsanida, Emmanuel Mikros, Ketty Soteriadou, Alexios-Leandros Skaltsounis. (2014) An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial glycogen synthase kinase-3 over leishmanial cdc2-related protein kinase 3. Parasites & Vectors, 7, 234

Alexandros Alexandratos, Joachim Clos, Martina Samiotaki, Antonia Efstathiou, George Panayotou, Ketty Soteriadou, Despina Smirlis. (2013) The loss of virulence of histone H1 overexpressing Leishmania donovani parasites is directly associated with a reduction of HSP83 rate of translation. Molecular Microbiology, 88 (5), 1015-1031


Dimitra Kovala-Demertzi, Athanassios Papageorgiou, Leuteris Papathanasis, Alexandros Alexandratos, Panagiotis Dalezis, John R. Miller, Mavroudis A. Demertzis. (2009) In vitro and in vivo antitumor activity of platinum(II) complexes with thiosemicarbazones derived from 2-formyl and 2-acetyl pyridine and containing ring incorporated at N(4)-position: Synthesis, spectroscopic study and crystal structure of platinum(II) complexes with thiosemicarbazones, potential anticancer agents. European Journal of Medicinal Chemistry, 44 (3), 1296-1302

Dimitra Kovala-Demertzi, Alexandros Alexandratos, Athanassios Papageorgiou, Paras Nath Yadav, Panagiotis Dalezis, Mavroudis A. Demertzis. (2008) Synthesis, characterization, crystal structures, in vitro and in vivo antitumor activity of palladium(II) and zinc(II) complexes with 2-formyl and 2-acetyl pyridine N(4)-1-(2-pyridyl)-piperazinyl thiosemicarbazone. Polyhedron, 27 (13), 2731-2738
1 Protocol published
Protein Sample Preparation for Proteomic Analysis in Leishmania donovani
Authors:  Alexandros Alexandratos and Despina Smirlis, date: 03/05/2014, view: 5874, Q&A: 0
Leishmania is a genus of trypanosomatid protozoa and is the parasite responsible for the disease leishmaniasis. These protozoa, regulate their gene expression in an atypical way, compared to other higher eukaryotes. The regulation of gene ...
11 Protocols reviewed
Detection of Membrane Protein Interactions by Cell-based Tango Assays
The Tango assay is a protein-protein interaction assay, in which a transcription factor (rTA) is fused to a membrane-bound protein via a linker that contains a cleavage site for TEV protease, whereas a soluble interaction partner is fused to TEV ...
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Quantifying Gene Expression Directly from FACS Using Hydrolysis (TaqMan) Probes on Flash-frozen Cells
Authors:  Kirsten A. Copren, Oyang Teng, Cassandra J. Adams, Cláudia Bispo and Michael Lee, date: 04/20/2018, view: 1379, Q&A: 0
The TaqMan Gene Expression Cells-to-CtTM Kit enables reverse transcription directly from cell lysates without the need for isolating RNA. The recommended input range for the lysis reaction is between 10-105 cells, though the ...
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