HongLok Lung University of Hong Kong
58 protocols

Jyotiska Chaudhuri Buck Institute for Research on Aging
28 protocols

Lee-Hwa Tai Universite de Sherbrooke
20 protocols

Pascal Fossat Université de Bordeaux
5 protocols

Reviewer
Clara Lubeseder-Martellato
  • Group leader, Technical University of Munich
Research focus
  • Cancer biology
  • Pancreatic ductal adenocarcinoma, endocytosis, GTPases, Ras signaling
  • 1 Author merit

Lab information

https://www.med2.mri.tum.de/en/research/ag-lubeseder-martellato.php

Publications

Lubeseder-Martellato, Hidalgo-Sastre, Heid, Boos, Briel, Schmid, Siveke (2017). Oncogenic KRas-induced increase in fluid-phase endocytosis is dependent on N-WASP and is required for the formation of pancreatic preneoplastic lesions. EBioMedicine 15, 90-99

Lubeseder-Martellato C, Hidalgo-Sastre A, Hartmann C, Alexandrow K, Kamyabi-Moghaddam Z, Sipos B, Wirth M, Neff F, Reichert M, Heid I, Schneider G, Braren R, Schmid RM, Siveke JT (2016). Membranous CD24 drives the epithelial phenotype of pancreatic cancer. Oncotarget.

Heid I, Lubeseder-Martellato C (equally contributed), Sipos B, Mazur PK, Lesina M, Schmid RM, Siveke JT (2011) Early requirement of Rac1 in a mouse model of pancreatic cancer. Gastroenterology 141: 719-730, 730 e711-717

Naschberger E, Lubeseder-Martellato C (equally contributed), Meyer N, Gessner R, Kremmer E, Gessner A, Sturzl M (2006) Human guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitis. Am J Pathol 169: 1088-1099

Lubeseder-Martellato C, Guenzi E, Jorg A, Topolt K, Naschberger E, Kremmer E, Zietz C, Tschachler E, Hutzler P, Schwemmle M, Matzen K, Grimm T, Ensoli B, Sturzl M (2002) Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases. Am J Pathol 161: 1749-1759: 409-420

Guenzi E, Topolt K, Cornali E, Lubeseder-Martellato C (equally contributed), Jorg A, Matzen K, Zietz C, Kremmer E, Nappi F, Schwemmle M, Hohenadl C, Barillari G, Tschachler E, Monini P, Ensoli B, Sturzl M (2001) The helical domain of GBP-1 mediates the inhibition of endothelial cell proliferation by inflammatory cytokines. EMBO J 20: 5568-5577
1 Protocol published
Isolation, Culture and Differentiation of Primary Acinar Epithelial Explants from Adult Murine Pancreas
Author:  Clara Lubeseder-Martellato, date: 07/05/2013, view: 6648, Q&A: 0
The adult pancreas possesses an intrinsic developmental plasticity whereby acinar cells can convert into ductal structures under some pathological conditions. Acinar tissue can be isolated from murine pancreas and kept in three-dimensional collagen ...
5 Protocols reviewed
Adoptive Transfer of Tumor Expanded Regulatory T Cells (Tregs)
Authors:  Felipe Vences-Catalán and Shoshana Levy, date: 08/20/2016, view: 4336, Q&A: 0
Regulatory T cells (Tregs), a subset of CD4+CD25+ T cells, infiltrate tumors and suppress antitumor activity of effector T and NK cells. Depletion of Tregs by anti CD25+ antibodies has been shown to reduce tumor ...
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Preparation of Recombinant Galectin-3 for Cancer Studies
Authors:  Kari Tyler, Sok-Hyong Lee and Erwin G. Van Meir, date: 01/05/2016, view: 4325, Q&A: 0
Galectin-3 is a member of a class of proteins termed Galectins, characterized by their ability to bind glycans containing β-galactose (Cummings and Liu, 2009). Galectin-3 binds preferentially to proteoglycans terminating with N-acetyllactosamine ...
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