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Coauthors
Carrie Graveel Center for Cancer and Cell Biology, Van Andel Research Institute, USA
1 protocol

Elizabeth Tovar Center for Cancer and Cell Biology, Van Andel Research Institute, USA
1 protocol

Curt J. Essenburg
  • Center for Cancer and Cell Biology, Van Andel Research Institute, USA
  • 1 Author merit

Education

B.S. in Biology, Grand Valley State University, 2005

Current Position

Research Technician, Van Andel Research Institute, Michigan, USA

Publications

  1. Linklater, E. S., Tovar, E. A., Essenburg, C. J., Turner, L., Madaj, Z., Winn, M. E., Melnik, M. K., Korkaya, H., Maroun, C. R., Christensen, J. G., Steensma, M. R., Boerner, J. L. and Graveel, C. R. (2016). Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers. Oncotarget. [Epub ahead of print]
  2. Sameni, M., Tovar, E. A., Essenburg, C. J., Chalasani, A., Linklater, E. S., Borgman, A., Cherba, D. M., Anbalagan, A., Winn, M. E., Graveel, C. R. and Sloane, B. F. (2016). Cabozantinib (XL184) Inhibits Growth and Invasion of Preclinical TNBC Models. Clin Cancer Res 22(4): 923-934.
  3. Xie, Q., Su, Y., Dykema, K., Johnson, J., Koeman, J., De Giorgi, V., Huang, A., Schlegel, R., Essenburg, C., Kang, L., Iwaya, K., Seki, S., Khoo, S. K., Zhang, B., Buonaguro, F., Marincola, F. M., Furge, K., Vande Woude, G. F. and Shinomiya, N. (2013). Overexpression of HGF Promotes HBV-Induced Hepatocellular Carcinoma Progression and Is an Effective Indicator for Met-Targeting Therapy. Genes Cancer 4(7-8): 247-260.
  4. Zhang, Y. W., Staal, B., Essenburg, C., Lewis, S., Kaufman, D. and Vande Woude, G. F. (2013). Strengthening context-dependent anticancer effects on non-small cell lung carcinoma by inhibition of both MET and EGFR. Mol Cancer Ther 12(8): 1429-1441.
  5. Xie, Q., Bradley, R., Kang, L., Koeman, J., Ascierto, M. L., Worschech, A., De Giorgi, V., Wang, E., Kefene, L., Su, Y., Essenburg, C., Kaufman, D. W., DeKoning, T., Enter, M. A., O'Rourke, T. J., Marincola, F. M. and Vande Woude, G. F. (2012). Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma. Proc Natl Acad Sci U S A 109(2): 570-575.
  6. Zhang, Y. W., Staal, B., Essenburg, C., Su, Y., Kang, L., West, R., Kaufman, D., Dekoning, T., Eagleson, B., Buchanan, S. G. and Vande Woude, G. F. (2010). MET kinase inhibitor SGX523 synergizes with epidermal growth factor receptor inhibitor erlotinib in a hepatocyte growth factor-dependent fashion to suppress carcinoma growth. Cancer Res 70(17): 6880-6890.
1 Protocol published
In vivo Efficacy Studies in Cell Line and Patient-derived Xenograft Mouse Models
Authors:  Elizabeth A. Tovar, Curt J. Essenburg and Carrie Graveel, date: 01/05/2017, view: 4642, Q&A: 0
In vivo xenograft models derived from human cancer cells have been a gold standard for evaluating the genetic drivers of cancer and are valuable preclinical models for evaluating the efficacy of cancer therapeutics. Recently, ...