Yong-Jing Gao Institute of Nautical Medicine, Nantong University, China
2 protocols

Peng-Bo Jing Institute of Nautical Medicine, Nantong University, China
2 protocols

Zhi-Jun Zhang
  • Institute of Nautical Medicine, Nantong University, China
Research focus
  • Neuroscience
  • 1 Author merit


Ph.D in Human Anatomy and Histoembryology, Soochow University, China, 2004

Current Position

Associate Professor in Medical School, Nantong University, Jiangsu China


  1. Jiang, B. C., Cao, D. L., Zhang, X., Zhang, Z. J., He, L. N., Li, C. H., Zhang, W. W., Wu, X. B., Berta, T., Ji, R. R. and Gao, Y. J. (2016). CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5. J Clin Invest 126(2): 745-761.
  2. Liu, X., Zhang, Z., Cheng, Z., Zhang, J., Xu, S., Liu, H., Jia, H. and Jin, Y. (2016). Spinal Heme Oxygenase-1 (HO-1) Exerts Antinociceptive Effects Against Neuropathic Pain in a Mouse Model of L5 Spinal Nerve Ligation. Pain Med 17(2): 220-229.
  3. Zhang, Q., Cao, D. L., Zhang, Z. J., Jiang, B. C. and Gao, Y. J. (2016). Chemokine CXCL13 mediates orofacial neuropathic pain via CXCR5/ERK pathway in the trigeminal ganglion of mice. J Neuroinflammation 13(1): 183.
  4. Qian, B., Li, F., Zhao, L. X., Dong, Y. L., Gao, Y. J. and Zhang, Z. J. (2016). Ligustilide Ameliorates Inflammatory Pain and Inhibits TLR4 Upregulation in Spinal Astrocytes Following Complete Freund's Adjuvant Peripheral Injection. Cell Mol Neurobiol 36(1): 143-149.
  5. Jiang, B. C., Sun, W. X., He, L. N., Cao, D. L., Zhang, Z. J. and Gao, Y. J. (2015). Identification of lncRNA expression profile in the spinal cord of mice following spinal nerve ligation-induced neuropathic pain. Mol Pain 11: 43.
  6. Guo, J. S., Jing, P. B., Wang, J. A., Zhang, R., Jiang, B. C., Gao, Y. J. and Zhang, Z. J. (2015). Increased autophagic activity in dorsal root ganglion attenuates neuropathic pain following peripheral nerve injury. Neurosci Lett 599: 158-163.
  7. Shen, Y., Zhang, Z. J., Zhu, M. D., Jiang, B. C., Yang, T. and Gao, Y. J. (2015). Exogenous induction of HO-1 alleviates vincristine-induced neuropathic pain by reducing spinal glial activation in mice. Neurobiol Dis 79: 100-110.
  8. Zhu, M. D., Zhao, L. X., Wang, X. T., Gao, Y. J. and Zhang, Z. J. (2014). Ligustilide inhibits microglia-mediated proinflammatory cytokines production and inflammatory pain. Brain Res Bull 109: 54-60.
  9. Lu, Y., Jiang, B. C., Cao, D. L., Zhang, Z. J., Zhang, X., Ji, R. R. and Gao, Y. J. (2014). TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-alpha and IL-1beta signaling. Pain 155(12): 2618-2629.
  10. Cao, D. L., Zhang, Z. J., Xie, R. G., Jiang, B. C., Ji, R. R. and Gao, Y. J. (2014). Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2. Exp Neurol 261: 328-336.
  11. Zhang, Z. J., Cao, D. L., Zhang, X., Ji, R. R. and Gao, Y. J. (2013). Chemokine contribution to neuropathic pain: respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons. Pain 154(10): 2185-2197.
  12. Hui, J., Zhang, Z. J., Zhang, X., Shen, Y. and Gao, Y. J. (2013). Repetitive hyperbaric oxygen treatment attenuates complete Freund's adjuvant-induced pain and reduces glia-mediated neuroinflammation in the spinal cord. J Pain 14(7): 747-758.
  13. Zhang, Z. J., Dong, Y. L., Lu, Y., Cao, S., Zhao, Z. Q. and Gao, Y. J. (2012). Chemokine CCL2 and its receptor CCR2 in the medullary dorsal horn are involved in trigeminal neuropathic pain. J Neuroinflammation 9: 136.
  14. Zhang, Z. J., Zhao, L. X., Cao, D. L., Zhang, X., Gao, Y. J. and Xia, C. (2012). Curcumin inhibits LPS-induced CCL2 expression via JNK pathway in C6 rat astrocytoma cells. Cell Mol Neurobiol 32(6): 1003-1010.
1 Protocol published
Authors:  Zhi-Jun Zhang, Peng-Bo Jing and Yong-Jing Gao, date: 11/20/2016, view: 12361, Q&A: 0
In order to explore the role of a specific gene/protein in the specific segment of the spinal cord, the technique of intraspinal injection is particularly used to deliver viral vectors targeting the specific gene/protein. These viral vectors can ...
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