Donatella de Pascale Institute of Protein Biochemistry, National Research Council, Italy
1 protocol

Fortunato Palma Esposito Institute of Protein Biochemistry, National Research Council, Italy
1 protocol

Pietro Tedesco National Research Council, Italia
1 protocol

Elia Di Schiavi
  • Institute of Bioscience and Bioresources, National Research Council, Italy
  • 1 Author merit


Ph.D. in Genetics, University of Naples Federico II, 2004

Current position

CNR Researcher and P.I. of the C. elegans Neurobiology Lab at the IBBR, CNR, Naples

Publications (since 2005)

  1. Ballestriero, F., Nappi, J., Zampi, G., Bazzicalupo, P., Di Schiavi, E. and Egan, S. (2016). Caenorhabditis elegans employs innate and learned aversion in response to bacterial toxic metabolites tambjamine and violacein. Sci Rep 6: 29284.

  2. Gallotta, I., Mazzarella, N., Donato, A., Esposito, A., Chaplin, J. C., Castro, S., Zampi, G., Battaglia, G. S., Hilliard, M. A., Bazzicalupo, P. and Di Schiavi, E. (2016). Neuron-specific knock-down of SMN1 causes neuron degeneration and death through an apoptotic mechanism. Hum Mol Genet.

  3. Tedesco, P., Visone, M., Parrilli, E., Tutino, M. L., Perrin, E., Maida, I., Fani, R., Ballestriero, F., Santos, R., Pinilla, C., Di Schiavi, E., Tegos, G. and de Pascale, D. (2015). Investigating the Role of the Host Multidrug Resistance Associated Protein Transporter Family in Burkholderia cepacia Complex Pathogenicity Using a Caenorhabditis elegans Infection Model. PLoS One 10(11): e0142883.

  4. Bianco, V., Paturzo, M., Marchesano, V., Gallotta, I., Di Schiavi, E. and Ferraro, P. (2015). Optofluidic holographic microscopy with custom field of view (FoV) using a linear array detector. Lab Chip 15(9): 2117-2124.

  5. Ballestriero, F., Daim, M., Penesyan, A., Nappi, J., Schleheck, D., Bazzicalupo, P., Di Schiavi, E. and Egan, S. (2014). Antinematode activity of Violacein and the role of the insulin/IGF-1 pathway in controlling violacein sensitivity in Caenorhabditis elegans. PLoS One 9(10): e109201.

  6. Network for Central Hypogonadism of Italian Societies of Endocrinology, o. A., Sexual, M., of Peadiatric, E. and Diabetes (2014). Kallmann's syndrome and normosmic isolated hypogonadotropic hypogonadism: two largely overlapping manifestations of one rare disorder. J Endocrinol Invest 37(5): 499-500.

  7. Flex, E., Jaiswal, M., Pantaleoni, F., Martinelli, S., Strullu, M., Fansa, E. K., Caye, A., De Luca, A., Lepri, F., Dvorsky, R., Pannone, L., Paolacci, S., Zhang, S. C., Fodale, V., Bocchinfuso, G., Rossi, C., Burkitt-Wright, E. M., Farrotti, A., Stellacci, E., Cecchetti, S., Ferese, R., Bottero, L., Castro, S., Fenneteau, O., Brethon, B., Sanchez, M., Roberts, A. E., Yntema, H. G., Van Der Burgt, I., Cianci, P., Bondeson, M. L., Cristina Digilio, M., Zampino, G., Kerr, B., Aoki, Y., Loh, M. L., Palleschi, A., Di Schiavi, E., Care, A., Selicorni, A., Dallapiccola, B., Cirstea, I. C., Stella, L., Zenker, M., Gelb, B. D., Cave, H., Ahmadian, M. R. and Tartaglia, M. (2014). Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis. Hum Mol Genet 23(16): 4315-4327.

  8. Di Schiavi, E. and Andrenacci, D. (2013). Invertebrate models of kallmann syndrome: molecular pathogenesis and new disease genes. Curr Genomics 14(1): 2-10.

  9. Vandamme, J., Lettier, G., Sidoli, S., Di Schiavi, E., Norregaard Jensen, O. and Salcini, A. E. (2012). The C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activity. PLoS Genet 8(5): e1002647.

  10. Esposito, G., Amoroso, M. R., Bergamasco, C., Di Schiavi, E. and Bazzicalupo, P. (2010). The G protein regulators EGL-10 and EAT-16, the Gialpha GOA-1 and the G(q)alpha EGL-30 modulate the response of the C. elegans ASH polymodal nociceptive sensory neurons to repellents. BMC Biol 8: 138.

  11. Cordeddu, V., Di Schiavi, E., Pennacchio, L. A., Ma'ayan, A., Sarkozy, A., Fodale, V., Cecchetti, S., Cardinale, A., Martin, J., Schackwitz, W., Lipzen, A., Zampino, G., Mazzanti, L., Digilio, M. C., Martinelli, S., Flex, E., Lepri, F., Bartholdi, D., Kutsche, K., Ferrero, G. B., Anichini, C., Selicorni, A., Rossi, C., Tenconi, R., Zenker, M., Merlo, D., Dallapiccola, B., Iyengar, R., Bazzicalupo, P., Gelb, B. D. and Tartaglia, M. (2009). Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair. Nat Genet 41(9): 1022-1026.

  12. Esposito, G., Di Schiavi, E., Bergamasco, C. and Bazzicalupo, P. (2007). Efficient and cell specific knock-down of gene function in targeted C. elegans neurons. Gene 395(1-2): 170-176.

  13. Di Schiavi, E., Riano, E., Heye, B., Bazzicalupo, P. and Rugarli, E. I. (2005). UMODL1/Olfactorin is an extracellular membrane-bound molecule with a restricted spatial expression in olfactory and vomeronasal neurons. Eur J Neurosci 21(12): 3291-3300.

1 Protocol published
Evaluation of Burkholderia cepacia Complex Bacteria Pathogenicity Using Caenorhabditis elegans
Authors:  Pietro Tedesco, Elia Di Schiavi, Fortunato Palma Esposito and Donatella de Pascale, date: 10/20/2016, view: 3880, Q&A: 0
This protocol describes two biological assays to evaluate pathogenicity of Burkholderia cepacia complex (Bcc) strains against the nematode Caenorhabditis elegans. Specifically, these two assays allow one to identify if the ...
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