Mansoureh Hashemi Functional neurosurgery research center, Shahid Beheshti University of medical sciences, Iran
2 protocols

Mahmoudreza Hadjighassem
  • Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Iran
Research focus
  • Neuroscience
  • 2 Author merit


Ph.D, Ottawa, Canada, 2008

Current position

Assistant professor, Neuroscience, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Iran


  1. Saffarzadeh, F., Eslamizade, M. J., Mousavi, S. M., Abraki, S. B., Hadjighassem, M. R. and Gorji, A. (2016). TRPV1 receptors augment basal synaptic transmission in CA1 and CA3 pyramidal neurons in epilepsy. Neuroscience 314: 170-178.
  2. Hashemi, M., Fallah, A., Aghayan, H. R., Arjmand, B., Yazdani, N., Verdi, J., Ghodsi, S. M., Miri, S. M. and Hadjighassem, M. (2016). A New Approach in Gene Therapy of Glioblastoma Multiforme: Human Olfactory Ensheathing Cells as a Novel Carrier for Suicide Gene Delivery. Mol Neurobiol 53(8): 5118-5128.
  3. Hadjighassem, M., Kamalidehghan, B., Shekarriz, N., Baseerat, A., Molavi, N., Mehrpour, M., Joghataei, M. T., Tondar, M., Ahmadipour, F. and Meng, G. Y. (2015). Oral consumption of alpha-linolenic acid increases serum BDNF levels in healthy adult humans. Nutr J 14: 20.
  4. Saffarzadeh, F., Eslamizade, M. J., Ghadiri, T., Modarres Mousavi, S. M., Hadjighassem, M. and Gorji, A. (2015). Effects of TRPV1 on the hippocampal synaptic plasticity in the epileptic rat brain. Synapse 69(7): 375-383.
  5. Alizadeh, R., Hassanzadeh, G., Soleimani, M., Joghataei, M. T., Siavashi, V., Khorgami, Z. and Hadjighassem, M. (2015). Gender and age related changes in number of dopaminergic neurons in adult human olfactory bulb. J Chem Neuroanat 69: 1-6.
  6. Eftekhari, S., Mehrabi, S., Soleimani, M., Hassanzadeh, G., Shahrokhi, A., Mostafavi, H., Hayat, P., Barati, M., Mehdizadeh, H., Rahmanzadeh, R., Hadjighassem, M. R. and Joghataei, M. T. (2014). BDNF modifies hippocampal KCC2 and NKCC1 expression in a temporal lobe epilepsy model. Acta Neurobiol Exp (Wars) 74(3): 276-287.
  7. Mostafavi, H., Khaksarian, M., Joghataei, M. T., Soleimani, M., Hassanzadeh, G., Eftekhari, S., Soleimani, M., Mousavizadeh, K., Estiri, H., Ahmadi, S. and Hadjighassem, M. R. (2014). Selective beta2 adrenergic agonist increases Cx43 and miR-451 expression via cAMP-Epac. Mol Med Rep 9(6): 2405-2410.
  8. Eftekhari, S., Mehvari Habibabadi, J., Najafi Ziarani, M., Hashemi Fesharaki, S. S., Gharakhani, M., Mostafavi, H., Joghataei, M. T., Beladimoghadam, N., Rahimian, E. and Hadjighassem, M. R. (2013). Bumetanide reduces seizure frequency in patients with temporal lobe epilepsy. Epilepsia 54(1): e9-12.
  9. Hadjighassem, M. R., Galaraga, K. and Albert, P. R. (2011). Freud-2/CC2D1B mediates dual repression of the serotonin-1A receptor gene. Eur J Neurosci 33(2): 214-223.
  10. Hadjighassem, M. R., Austin, M. C., Szewczyk, B., Daigle, M., Stockmeier, C. A. and Albert, P. R. (2009). Human Freud-2/CC2D1B: a novel repressor of postsynaptic serotonin-1A receptor expression. Biol Psychiatry 66(3): 214-222.
2 Protocols published
Primary Olfactory Ensheathing Cell Culture from Human Olfactory Mucosa Specimen
Authors:  Mansoureh Hashemi and Mahmoudreza Hadjighassem, date: 05/20/2017, view: 5576, Q&A: 0
The human olfactory mucosa is located in the middle and superior turbinates, and the septum of nasal cavity. Olfactory mucosa plays an important role in detection of odours and it is also the only nervous tissue that is exposed to the external ...
Preparation of Primary Astrocyte Culture Derived from Human Glioblastoma Multiforme Specimen
Authors:  Mansoureh Hashemi and Mahmoudreza Hadjighassem, date: 04/20/2017, view: 7799, Q&A: 0
Glioblastoma multiforme (GBM) is a grade 4 astrocytoma tumor in central nervous system. Astrocytes can be isolated from human GBM. Study of astrocytes can provide insights about the formation, progression and recurrence of glioblastoma. For using ...
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