Search
Coauthors
Philippe Bastiaens Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Germany
1 protocol

Jens Christmann Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Germany
1 protocol

Martin Masip Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Germany
1 protocol

Jan Huebinger Max Planck Institute of Molecular Physiology
1 protocol

Frank Wehner
  • Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Germany
  • 1 Author merit

Current position

Head, Group of Cell Physiology, Max-Planck-Institute of Molecular Physiology Dortmund, Germany
Professor, Technical University Dortmund, Germany, 1993

Publications

  1. Masip, M. E., Huebinger, J., Christmann, J., Sabet, O., Wehner, F., Konitsiotis, A., Fuhr, G. R. and Bastiaens, P. I. (2016). Reversible cryo-arrest for imaging molecules in living cells at high spatial resolution. Nat Methods 13(8): 665-672.
  2. Christmann, J., Azer, L., Dorr, D., Fuhr, G. R., Bastiaens, P. I. and Wehner, F. (2016). Adaptive responses of cell hydration to a low temperature arrest. J Physiol 594(6): 1663-1676.
  3. Numata, T., Sato, K., Christmann, J., Marx, R., Mori, Y., Okada, Y. and Wehner, F. (2012). The DeltaC splice-variant of TRPM2 is the hypertonicity-induced cation channel in HeLa cells, and the ecto-enzyme CD38 mediates its activation. J Physiol 590(5): 1121-1138.
  4. Bondarava, M., Li, T., Endl, E. and Wehner, F. (2009). alpha-ENaC is a functional element of the hypertonicity-induced cation channel in HepG2 cells and it mediates proliferation. Pflugers Arch 458(4): 675-687.
  5. Numata, T., Sato, K., Okada, Y. and Wehner, F. (2008). Hypertonicity-induced cation channels rescue cells from staurosporine-elicited apoptosis. Apoptosis 13(7): 895-903.
  6. Wehner, F., Noren-Muller, A., Muller, O., Reis-Correa, I., Jr., Giannis, A. and Waldmann, H. (2008). Indoloquinolizidine derivatives as novel and potent apoptosis inducers and cell-cycle blockers. Chembiochem 9(3): 401-405.
  7. Plettenberg, S., Weiss, E. C., Lemor, R. and Wehner, F. (2008). Subunits alpha, beta and gamma of the epithelial Na+ channel (ENaC) are functionally related to the hypertonicity-induced cation channel (HICC) in rat hepatocytes. Pflugers Arch 455(6): 1089-1095.
  8. Happel, P., Wehner, F. and Dietzel, I. D. (2008). Scanning ion conductance microscopy – a tool to investigate electrolyte-nonconductor interfaces. Mod Res Educ Top Microsc 3: 968-975.
  9. Wehner, F., Numata, T., Subramanyan, M., Takahashi, N. and Okada, Y. (2007). Signalling events employed in the hypertonic activation of cation channels in HeLa cells. Cell Physiol Biochem 20(1-4): 75-82.
  10. Weiss, E. C., Wehner, F. and Lemor, R. M. (2007). Measuring cell volume regulation with time resolved acoustic microscopy. Acoust Imag 28: 73-80.
  11. Bierhals, K., Sondersorg, A. C., Lin, C. T., Rosenbaum, C., Waldmann, H. and Wehner, F. (2007). The epsilon-isoform of PKC mediates the hypertonic activation of cation channels in confluent monolayers of rat hepatocytes. Cell Physiol Biochem 20(5): 397-404.
  12. Olsen, H., ter Veld, F., Herbrand, U., Ahmadian, M. R., Kinne, R. K. and Wehner, F. (2007). Differential regulation of cell volume and shape in confluent rat hepatocytes under hypertonic stress. Cell Physiol Biochem 19(5-6): 259-268.
  13. Numata, T., Wehner, F. and Okada, Y. (2007). 2-aminoethoxydiphenyl borate is an effective blocker of hypertonicity-induced cation channels in HeLa cells. J Physiol Sci 57: 235-238.
  14. Shimizu, T., Wehner, F. and Okada, Y. (2006). Inhibition of hypertonicity-induced cation channels sensitizes HeLa cells to shrinkage-induced apoptosis. Cell Physiol Biochem 18(6): 295-302.
  15. Wehner, F., Bondarava, M., ter Veld, F., Endl, E., Nurnberger, H. R. and Li, T. (2006). Hypertonicity-induced cation channels. Acta Physiol (Oxf) 187(1-2): 21-25.
  16. Wehner, F. (2006). Cell volume-regulated cation channels. Contrib Nephrol 152: 25-53.
  17. Li, T., ter Veld, F., Nurnberger, H. R. and Wehner, F. (2005). A novel hypertonicity-induced cation channel in primary cultures of human hepatocytes. FEBS Lett 579(10): 2087-2091.
1 Protocol published
Reversible Cryo-arrests of Living Cells to Pause Molecular Movements for High-resolution Imaging
Fluorescence live-cell imaging by single molecule localization microscopy (SMLM) or fluorescence lifetime imaging microscopy (FLIM) in principle allows for the spatio-temporal observation of molecular patterns in individual, living cells. However, ...