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Coauthors
Christopher Tate MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, UK
2 protocols

Reviewer
Byron Carpenter
  • Research Fellow, University of Warwick
Research focus
  • Biochemistry
  • G protein
    GPCR
    X-ray crystallography
    Synthetic biology
    Protein engineering
  • 2 Author merit

Education

PhD in Structural Biology, University of Sheffield, 2010

Publications

2 Protocols published
Expression and Purification of Mini G Proteins from Escherichia coli
Authors:  Byron Carpenter and Christopher G. Tate, date: 04/20/2017, view: 3846, Q&A: 0
Heterotrimeric G proteins modulate intracellular signalling by transducing information from cell surface G protein-coupled receptors (GPCRs) to cytoplasmic effector proteins. Structural and functional characterisation of GPCR–G protein complexes is ...
Expression, Purification and Crystallisation of the Adenosine A2A Receptor Bound to an Engineered Mini G Protein
Authors:  Byron Carpenter and Christopher G. Tate, date: 04/20/2017, view: 3694, Q&A: 0
G protein-coupled receptors (GPCRs) promote cytoplasmic signalling by activating heterotrimeric G proteins in response to extracellular stimuli such as light, hormones and nucleosides. Structure determination of GPCR–G protein complexes is central ...