Shihuan Kuang Department of Animal Science, Purdue University, USA
3 protocols

Yaohui Nie Department of Animal Sciences, Purdue University, USA
1 protocol

Timothy P. Gavin
  • Department of Health and Kinesiology and Max E. Wastl Human Performance Laboratory, Purdue University, USA
  • 1 Author merit


Postdoctoral Fellowship in Skeletal Muscle Angiogenesis, Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA, 1996

Current position

Department Head, Department of Health and Kinesiology, Purdue University (2012-present)       
Professor, Department of Health and Kinesiology, Purdue University (2012-present)       
Adjunct Professor, Department of Kinesiology, East Carolina University (2012-present)       


  1. Nie, Y., Gavin, T. P. and Kuang, S. (2015). Measurement of resting energy metabolism in mice using oxymax open circuit indirect calorimeter. Bio-protocol 5(18): e1602.
  2. Gavin, T. P., Kraus, R. M., Carrithers, J. A., Garry, J. P. and Hickner, R. C. (2014). Aging and the Skeletal Muscle Angiogenic Response to Exercise in Women. J Gerontol A Biol Sci Med Sci.
  3. La Favor, J. D., Kraus, R. M., Carrithers, J. A., Roseno, S. L., Gavin, T. P. and Hickner, R. C. (2014). Sex differences with aging in nutritive skeletal muscle blood flow: impact of exercise training, nitric oxide, and alpha-adrenergic-mediated mechanisms. Am J Physiol Heart Circ Physiol 307(4): H524-532.
  4. Camarillo, I. G., Clah, L., Zheng, W., Zhou, X., Larrick, B., Blaize, N., Breslin, E., Patel, N., Johnson, D., Teegarden, D., Donkin, S. S., Gavin, T. P. and Newcomer, S. (2014). Maternal exercise during pregnancy reduces risk of mammary tumorigenesis in rat offspring. Eur J Cancer Prev 23(6): 502-505.
  5. Gavin, T. P., Ernst, J. M., Caudill, S. E., Dohm, G. L., Pories, W. J., Dar, M. and Reed, M. A. (2014). Insulin sensitivity is related to glycemic control in type 2 diabetes and diabetes remission after Roux-en Y gastrc bypass. Surgery 155(6): 1036-1043.
  6. Fisher-Wellman, K. H., Weber, T. M., Cathey, B. L., Brophy, P. M., Gilliam, L. A., Kane, C. L., Maples, J. M., Gavin, T. P., Houmard, J. A. and Neufer, P. D. (2014). Mitochondrial respiratory capacity and content are normal in young insulin-resistant obese humans. Diabetes 63(1): 132-141.
  7. Gavin, T. P., Van Meter, J. B., Brophy, P. M., Dubis, G. S., Potts, K. N. and Hickner, R. C. (2012). Comparison of a field-based test to estimate functional threshold power and power output at lactate threshold. J Strength Cond Res 26(2): 416-421.
  8. Reed, M. A., Pories, W. J., Chapman, W., Pender, J., Bowden, R., Barakat, H., Gavin, T. P., Green, T., Tapscott, E., Zheng, D., Shankley, N., Yieh, L., Polidori, D., Piccoli, S. P., Brenner-Gati, L. and Dohm, G. L. (2011). Roux-en-Y gastric bypass corrects hyperinsulinemia implications for the remission of type 2 diabetes. J Clin Endocrinol Metab 96(8): 2525-2531.
  9. Perry, C. G., Kane, D. A., Lin, C. T., Kozy, R., Cathey, B. L., Lark, D. S., Kane, C. L., Brophy, P. M., Gavin, T. P., Anderson, E. J. and Neufer, P. D. (2011). Inhibiting myosin-ATPase reveals a dynamic range of mitochondrial respiratory control in skeletal muscle. Biochem J 437(2): 215-222.
  10. Boyle, K. E., Canham, J. P., Consitt, L. A., Zheng, D., Koves, T. R., Gavin, T. P., Holbert, D., Neufer, P. D., Ilkayeva, O., Muoio, D. M. and Houmard, J. A. (2011). A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals. J Clin Endocrinol Metab 96(3): 775-781.
  11. Gavin, T. P., Sloan, R. C., 3rd, Lukosius, E. Z., Reed, M. A., Pender, J. R., Boghossian, V., Carter, J. J., McKernie, R. D., Parikh, K., Price, J. W., Tapscott, E. B., Pories, W. J. and Dohm, G. L. (2011). Duodenal-jejunal bypass surgery does not increase skeletal muscle insulin signal transduction or glucose disposal in Goto-Kakizaki type 2 diabetic rats. Obes Surg 21(2): 231-237.
  12. Gavin, T. P. (2009). Basal and exercise-induced regulation of skeletal muscle capillarization. Exerc Sport Sci Rev 37(2): 86-92.
  13. Zwetsloot, K. A., Westerkamp, L. M., Holmes, B. F. and Gavin, T. P. (2008). AMPK regulates basal skeletal muscle capillarization and VEGF expression, but is not necessary for the angiogenic response to exercise. J Physiol 586(Pt 24): 6021-6035.
  14. Wooldridge, A. A., Fortner, C. N., Lontay, B., Akimoto, T., Neppl, R. L., Facemire, C., Datto, M. B., Kwon, A., McCook, E., Li, P., Wang, S., Thresher, R. J., Miller, S. E., Perriard, J. C., Gavin, T. P., Hickner, R. C., Coffman, T. M., Somlyo, A. V., Yan, Z. and Haystead, T. A. (2008). Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle. J Biol Chem 283(17): 11850-11859.
  15. Gavin, T. P., Ruster, R. S., Carrithers, J. A., Zwetsloot, K. A., Kraus, R. M., Evans, C. A., Knapp, D. J., Drew, J. L., McCartney, J. S., Garry, J. P. and Hickner, R. C. (2007). No difference in the skeletal muscle angiogenic response to aerobic exercise training between young and aged men. J Physiol 585(Pt 1): 231-239.
  16. Gavin, T. P., Drew, J. L., Kubik, C. J., Pofahl, W. E. and Hickner, R. C. (2007). Acute resistance exercise increases skeletal muscle angiogenic growth factor expression. Acta Physiol (Oxf) 191(2): 139-146.
  17. Focht, B. C., Knapp, D. J., Gavin, T. P., Raedeke, T. D. and Hickner, R. C. (2007). Affective and self-efficacy responses to acute aerobic exercise in sedentary older and younger adults. J Aging Phys Act 15(2): 123-138.
  18. Olfert, I. M., Breen, E. C., Gavin, T. P. and Wagner, P. D. (2006). Temporal thrombospondin-1 mRNA response in skeletal muscle exposed to acute and chronic exercise. Growth Factors 24(4): 253-259.
  19. Gavin, T. P., Westerkamp, L. M. and Zwetsloot, K. A. (2006). Soleus, plantaris and gastrocnemius VEGF mRNA responses to hypoxia and exercise are preserved in aged compared with young female C57BL/6 mice. Acta Physiol (Oxf) 188(2): 113-121.
  20. Ryan, N. A., Zwetsloot, K. A., Westerkamp, L. M., Hickner, R. C., Pofahl, W. E. and Gavin, T. P. (2006). Lower skeletal muscle capillarization and VEGF expression in aged vs. young men. J Appl Physiol (1985) 100(1): 178-185.
  21. Croley, A. N., Zwetsloot, K. A., Westerkamp, L. M., Ryan, N. A., Pendergast, A. M., Hickner, R. C., Pofahl, W. E. and Gavin, T. P. (2005). Lower capillarization, VEGF protein, and VEGF mRNA response to acute exercise in the vastus lateralis muscle of aged vs. young women. J Appl Physiol (1985) 99(5): 1872-1879.
  22. Gavin, T. P., Stallings, H. W., 3rd, Zwetsloot, K. A., Westerkamp, L. M., Ryan, N. A., Moore, R. A., Pofahl, W. E. and Hickner, R. C. (2005). Lower capillary density but no difference in VEGF expression in obese vs. lean young skeletal muscle in humans. J Appl Physiol (1985) 98(1): 315-321.
1 Protocol published
Measurement of Resting Energy Metabolism in Mice Using Oxymax Open Circuit Indirect Calorimeter
Authors:  Yaohui Nie, Timothy P. Gavin and Shihuan Kuang, date: 09/20/2015, view: 3145, Q&A: 0
Indirect calorimeter is a powerful tool to monitor resting energy metabolism through the measurement of oxygen (O2) consumption and carbon dioxide (CO2) production. From the measurement of VO2 and VCO2, ...