Jeffrey Milush University of California San Francisco
1 protocol

Vanessa A. York
  • Division of Experimental Medicine, University of California, San Francisco, USA
Research focus
  • Immunology
  • 1 Author merit


B.S. in Biological Sciences with an Emphasis in Molecular and Cellular Biology, UC Davis, 2005

Current position

Staff Research Associate III-Supervisor, Division of Experimental Medicine, University of California, San Francisco, San Francisco, USA

Publications (since 2008)

  1. Raposo, R. A., Gupta, R., Abdel-Mohsen, M., Dimon, M., Debbaneh, M., Jiang, W., York, V. A., Leadabrand, K. S., Brown, G., Malakouti, M., Arron, S., Kuebler, P. J., Wu, J. J., Pillai, S. K., Nixon, D. F. and Liao, W. (2015). Antiviral gene expression in psoriasis. J Eur Acad Dermatol Venereol. (Epub ahead of print)
  2. Gurfein, B. T., Davidenko, O., Premenko-Lanier, M., Milush, J. M., Acree, M., Dallman, M. F., Touma, C., Palme, R., York, V. A., Fromentin, G., Darcel, N., Nixon, D. F. and Hecht, F. M. (2014). Environmental enrichment alters splenic immune cell composition and enhances secondary influenza vaccine responses in mice. Mol Med 20: 179-190.
  3. Milush, J. M., Lopez-Verges, S., York, V. A., Deeks, S. G., Martin, J. N., Hecht, F. M., Lanier, L. L. and Nixon, D. F. (2013). CD56negCD16(+) NK cells are activated mature NK cells with impaired effector function during HIV-1 infection. Retrovirology 10: 158.
  4. de Mulder, M., York, V. A., Wiznia, A. A., Michaud, H. A., Nixon, D. F., Holguin, A. and Rosenberg, M. G. (2014). HIV-1 drug resistance prevalence, drug susceptibility and variant characterization in the Jacobi Medical Center paediatric cohort, Bronx, NY, USA. HIV Med 15(3): 135-143.
  5. Champiat, S., Garrison, K. E., Raposo, R. A., Burwitz, B. J., Reed, J., Tandon, R., York, V. A., Newman, L. P., Nimityongskul, F. A., Wilson, N. A., Almeida, R. R., Martin, J. N., Deeks, S. G., Rosenberg, M. G., Wiznia, A. A., Spotts, G. E., Pilcher, C. D., Hecht, F. M., Ostrowski, M. A., Sacha, J. B. and Nixon, D. F. (2013). T cells target APOBEC3 proteins in human immunodeficiency virus type 1-infected humans and simian immunodeficiency virus-infected Indian rhesus macaques. J Virol 87(11): 6073-6080.
  6. Batista, M. D., Tincati, C., Milush, J. M., Ho, E. L., Ndhlovu, L. C., York, V. A., Kallas, E. G., Kalil, J., Keating, S. M., Norris, P. J., Chang, D., Unemori, P., Leslie, K. S., Maurer, T., Liao, W. and Nixon, D. F. (2013). CD57 expression and cytokine production by T cells in lesional and unaffected skin from patients with psoriasis. PLoS One 8(2): e52144.
  7. Batista, M. D., Ho, E. L., Kuebler, P. J., Milush, J. M., Lanier, L. L., Kallas, E. G., York, V. A., Chang, D., Liao, W., Unemori, P., Leslie, K. S., Maurer, T. and Nixon, D. F. (2013). Skewed distribution of natural killer cells in psoriasis skin lesions. Exp Dermatol 22(1): 64-66.
  8. de Vos, G., Milush, J. M., Aaron, J., Pichardo, Y., York, V. A., Nazari, R., Rosenstreich, D., Nixon, D. F. and Wiznia, A. (2012). Peripheral CD8+ T-cell levels are decreased in atopic wheezing children aged less than 4 years. J Investig Allergol Clin Immunol 22(6): 442-444.
  9. Tandon, R., Giret, M. T., Sengupta, D., York, V. A., Wiznia, A. A., Rosenberg, M. G., Kallas, E. G., Ndhlovu, L. C. and Nixon, D. F. (2012). Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children. PLoS One 7(9): e45733.
  10. Tandon, R., SenGupta, D., Ndhlovu, L. C., Vieira, R. G., Jones, R. B., York, V. A., Vieira, V. A., Sharp, E. R., Wiznia, A. A., Ostrowski, M. A., Rosenberg, M. G. and Nixon, D. F. (2011). Identification of human endogenous retrovirus-specific T cell responses in vertically HIV-1-infected subjects. J Virol 85(21): 11526-11531.
  11. Lopez-Verges, S., Milush, J. M., Schwartz, B. S., Pando, M. J., Jarjoura, J., York, V. A., Houchins, J. P., Miller, S., Kang, S. M., Norris, P. J., Nixon, D. F. and Lanier, L. L. (2011). Expansion of a unique CD57(+)NKG2Chi natural killer cell subset during acute human cytomegalovirus infection. Proc Natl Acad Sci U S A 108(36): 14725-14732.
  12. Ndhlovu, L. C., Leal, F. E., Hasenkrug, A. M., Jha, A. R., Carvalho, K. I., Eccles-James, I. G., Bruno, F. R., Vieira, R. G., York, V. A., Chew, G. M., Jones, R. B., Tanaka, Y., Neto, W. K., Sanabani, S. S., Ostrowski, M. A., Segurado, A. C., Nixon, D. F. and Kallas, E. G. (2011). HTLV-1 tax specific CD8+ T cells express low levels of Tim-3 in HTLV-1 infection: implications for progression to neurological complications. PLoS Negl Trop Dis 5(4): e1030.
  13. SenGupta, D., Tandon, R., Vieira, R. G., Ndhlovu, L. C., Lown-Hecht, R., Ormsby, C. E., Loh, L., Jones, R. B., Garrison, K. E., Martin, J. N., York, V. A., Spotts, G., Reyes-Teran, G., Ostrowski, M. A., Hecht, F. M., Deeks, S. G. and Nixon, D. F. (2011). Strong human endogenous retrovirus-specific T cell responses are associated with control of HIV-1 in chronic infection. J Virol 85(14): 6977-6985.
  14. Lopez-Verges, S., Milush, J. M., Pandey, S., York, V. A., Arakawa-Hoyt, J., Pircher, H., Norris, P. J., Nixon, D. F. and Lanier, L. L. (2010). CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset. Blood 116(19): 3865-3874.
  15. Milush, J. M., Long, B. R., Snyder-Cappione, J. E., Cappione, A. J., 3rd, York, V. A., Ndhlovu, L. C., Lanier, L. L., Michaelsson, J. and Nixon, D. F. (2009). Functionally distinct subsets of human NK cells and monocyte/DC-like cells identified by coexpression of CD56, CD7, and CD4. Blood 114(23): 4823-4831.
  16. Jha, A. R., Pillai, S. K., York, V. A., Sharp, E. R., Storm, E. C., Wachter, D. J., Martin, J. N., Deeks, S. G., Rosenberg, M. G., Nixon, D. F. and Garrison, K. E. (2009). Cross-sectional dating of novel haplotypes of HERV-K 113 and HERV-K 115 indicate these proviruses originated in Africa before Homo sapiens. Mol Biol Evol 26(11): 2617-2626.
  17. Garrison, K. E., Champiat, S., York, V. A., Agrawal, A. T., Kallas, E. G., Martin, J. N., Hecht, F. M., Deeks, S. G. and Nixon, D. F. (2009). Transcriptional errors in human immunodeficiency virus type 1 generate targets for T-cell responses. Clin Vaccine Immunol 16(9): 1369-1371.
  18. Willberg, C. B., McConnell, J. J., Eriksson, E. M., Bragg, L. A., York, V. A., Liegler, T. J., Hecht, F. M., Grant, R. M. and Nixon, D. F. (2008). Immunity to HIV-1 is influenced by continued natural exposure to exogenous virus. PLoS Pathog 4(10): e1000185.
1 Protocol published
Ex vivo Human Natural Killer (NK) Cell Stimulation and Intracellular IFNγ and CD107a Cytokine Staining
Authors:  Vanessa A. York and Jeffrey M. Milush, date: 06/20/2015, view: 14113, Q&A: 1
Natural killer (NK) cells comprise 5–20% of peripheral blood mononuclear cells (PBMC) in humans. In addition to their fundamental roles in the defense against viral infections and tumor surveillance, NK cells help shape adaptive immune responses ...
We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.