Education
Ph.D. in Sciences, ISREC, University of Lausanne, 2001
Current position
Assistant Professor, Immunology Programme, Department of Microbiology, National University of Singapore
Publications (since 2005)
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Lam R.A., Chwee J.Y., Le Bert N., Sauer M., Pogge von Strandmann E., and Gasser S. (2013). Regulation of Self-Ligands for Activating Natural Killer Cell Receptors. Ann. of Med. In press.
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Croxford, J. L., Tang, M. L., Pan, M. F., Huang, C. W., Kamran, N., Phua, C. M., Chng, W. J., Ng, S. B., Raulet, D. H. and Gasser, S. (2013). ATM-dependent spontaneous regression of early Emu-myc-induced murine B-cell leukemia depends on natural killer and T cells. Blood 121(13): 2512-2521.
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Kamran, N., Takai, Y., Miyoshi, J., Biswas, S. K., Wong, J. S. and Gasser, S. (2013). Toll-like receptor ligands induce expression of the costimulatory molecule CD155 on antigen-presenting cells. PLoS ONE 8(1): e54406.
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Raulet, D. H., Gasser, S., Gowen, B. G., Deng, W. and Jung, H. (2013). Regulation of ligands for the NKG2D activating receptor. Annu Rev Immunol 31: 413-441.
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Tang, M.L.F., and Gasser, S. (2013). ATM activation mediates anticancer immunosurveillance by natural killer and T cells. OncoImmunology 2: e24438.
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Ho, S. S. and Gasser, S. (2013). NKG2D ligands link oncogenic RAS to innate immunity. Oncoimmunology 2(1): e22244.
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Ge, M. Q., Ho, A. W., Tang, Y., Wong, K. H., Chua, B. Y., Gasser, S. and Kemeny, D. M. (2012). NK cells regulate CD8+ T cell priming and dendritic cell migration during influenza A infection by IFN-gamma and perforin-dependent mechanisms. J Immunol 189(5): 2099-2109.
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Liu, X. V., Ho, S. S., Tan, J. J., Kamran, N. and Gasser, S. (2012). Ras activation induces expression of Raet1 family NK receptor ligands. J Immunol 189(4): 1826-1834.
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Yeo, Y. A., Martinez Gomez, J. M., Croxford, J. L., Gasser, S., Ling, E. A. and Schwarz, H. (2012). CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species. J Neuroinflammation 9: 173.
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Xiong, G.M., and Gasser, S. (2011). Integration of the DNA Damage Response with Innate Immune Pathways. Intech: 715-737.
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Croxford, J. L. and Gasser, S. (2011). Damage control: how HIV survives the editor APOBEC3G. Nat Immunol 12(10): 925-927.
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Fine, J. H., Chen, P., Mesci, A., Allan, D. S., Gasser, S., Raulet, D. H. and Carlyle, J. R. (2010). Chemotherapy-induced genotoxic stress promotes sensitivity to natural killer cell cytotoxicity by enabling missing-self recognition. Cancer Res 70(18): 7102-7113.
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Lee, S. K. and Gasser, S. (2010). The role of natural killer cells in cancer therapy. Front Biosci (Elite Ed) 2: 380-391.
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Gasser, S. (2007). DNA damage response and development of targeted cancer treatments. Ann Med 39(6): 457-464.
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Gasser, S. and Raulet, D. H. (2006). Activation and self-tolerance of natural killer cells. Immunol Rev 214: 130-142..
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Gasser, S. and Raulet, D. (2006). The DNA damage response, immunity and cancer. Semin Cancer Biol 16(5): 344-347.
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Bianchi, T., Gasser, S., Trumpp, A. and MacDonald, H. R. (2006). c-Myc acts downstream of IL-15 in the regulation of memory CD8 T-cell homeostasis. Blood 107(10): 3992-3999.
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Gasser, S. and Raulet, D. H. (2006). The DNA damage response arouses the immune system. Cancer Res 66(8): 3959-3962.
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Gasser, S., Orsulic, S., Brown, E. J. and Raulet, D. H. (2005). The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature 436(7054): 1186-1190.