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Coauthors
I. Jolanda de Vries Department of Tumor Immunology, RIMLS, The Netherlands
1 protocol

Leon Massuger Department of Obstetrics & Gynecology, Radboudumc, The Netherlands
1 protocol

Ruurd Torensma Department of Tumor Immunology, Radboudumc, The Netherlands
1 protocol

Tjitske Duiveman-de Boer Department of Tumor Immunology, Radboudumc, The Netherlands
1 protocol

Ghaith Bakdash
  • Department of Tumor Immunology, Radboudumc, The Netherlands
  • 1 Author merit

Education

Ph.D, Academic Medical Center, University of Amsterdam, The Netherlands, 2012

Current position

Immunologist, Allergic Inflammation DPU, GSK, UK

Publications

  1. Mathan, T. S., Textor, J., Skold, A. E., Reinieren-Beeren, I., van Oorschot, T., Bruning, M., Figdor, C. G., Buschow, S. I., Bakdash, G. and de Vries, I. J. (2017). Harnessing RNA sequencing for global, unbiased evaluation of two new adjuvants for dendritic-cell immunotherapy. Oncotarget.
  2. van Beek, J. J., Gorris, M. A., Skold, A. E., Hatipoglu, I., Van Acker, H. H., Smits, E. L., de Vries, I. J. and Bakdash, G. (2016). Human blood myeloid and plasmacytoid dendritic cells cross activate each other and synergize in inducing NK cell cytotoxicity. Oncoimmunology 5(10): e1227902.
  3. Bakdash, G., Buschow, S. I., Gorris, M. A., Halilovic, A., Hato, S. V., Skold, A. E., Schreibelt, G., Sittig, S. P., Torensma, R., Duiveman-de Boer, T., Schroder, C., Smits, E. L., Figdor, C. G. and de Vries, I. J. (2016). Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines. Cancer Res 76(15): 4332-4346.
  4. Bakdash, G. and Srinivas, M. (2016). Tracking lymphocytes in vivo. In: Kuperman, V. (Ed). Fluorine Magnetic Resonance Imaging 1st Edition. Pan Stanford Publishing, ISBN-13: 978-9814745314.
  5. van Beek, J. J. P., Martens, A., Bakdash, G. and de Vries, I. J. M. (2016). Innate lymphoid cells in tumor immunity. Biomedicines 4(1).
  6. Sittig, S. P., Bakdash, G., Weiden, J., Skold, A. E., Tel, J., Figdor, C. G., de Vries, I. J. and Schreibelt, G. (2016). A Comparative Study of the T Cell Stimulatory and Polarizing Capacity of Human Primary Blood Dendritic Cell Subsets. Mediators Inflamm 2016: 3605643.
  7. Kreutz, M., Bakdash, G., Dolen, Y., Skold, A. E., van Hout-Kuijer, M. A., de Vries, I. J. and Figdor, C. G. (2015). Type I IFN-mediated synergistic activation of mouse and human DC subsets by TLR agonists. Eur J Immunol 45(10): 2798-2809.
  8. Skold, A. E., van Beek, J. J., Sittig, S. P., Bakdash, G., Tel, J., Schreibelt, G. and de Vries, I. J. (2015). Protamine-stabilized RNA as an ex vivo stimulant of primary human dendritic cell subsets. Cancer Immunol Immunother 64(11): 1461-1473.
  9. Bakdash, G., Vogelpoel, L. T., van Capel, T. M., Kapsenberg, M. L. and de Jong, E. C. (2015). Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. Mucosal Immunol 8(2): 265-278.
  10. Bakdash, G., van Capel, T. M., Mason, L. M., Kapsenberg, M. L. and de Jong, E. C. (2014). Vitamin D3 metabolite calcidiol primes human dendritic cells to promote the development of immunomodulatory IL-10-producing T cells. Vaccine 32(47): 6294-6302.
  11. Bakdash, G., Schreurs, I., Schreibelt, G. and Tel, J. (2014). Crosstalk between dendritic cell subsets and implications for dendritic cell-based anticancer immunotherapy. Expert Rev Clin Immunol 10(7): 915-926.
  12. Bakdash, G., Sittig, S. P., van Dijk, T., Figdor, C. G. and de Vries, I. J. (2013). The nature of activatory and tolerogenic dendritic cell-derived signal II. Front Immunol 4: 53.
  13. Bakdash, G., Schneider, L. P., van Capel, T. M., Kapsenberg, M. L., Teunissen, M. B. and de Jong, E. C. (2013). Intradermal application of vitamin D3 increases migration of CD14+ dermal dendritic cells and promotes the development of Foxp3+ regulatory T cells. Hum Vaccin Immunother 9(2): 250-258.
  14. de Groot, R., van Beelen, A. J., Bakdash, G., Taanman-Kueter, E. W., de Jong, E. C. and Kapsenberg, M. L. (2012). Viral dsRNA-activated human dendritic cells produce IL-27, which selectively promotes cytotoxicity in naive CD8+ T cells. J Leukoc Biol 92(3): 605-610.
  15. van der Aar, A. M., Sibiryak, D. S., Bakdash, G., van Capel, T. M., van der Kleij, H. P., Opstelten, D. J., Teunissen, M. B., Kapsenberg, M. L. and de Jong, E. C. (2011). Vitamin D3 targets epidermal and dermal dendritic cells for induction of distinct regulatory T cells. J Allergy Clin Immunol 127(6): 1532-1540 e1537.
1 Protocol published
Isolation of Mononuclear Cell Populations from Ovarian Carcinoma Ascites
Ovarian cancer is one of the most fatal tumors in women. Due to a lack of symptoms and adequate screening methods, patients are diagnosed at advanced stages with extensive tumor burden (Jelovac and Armstrong, 2011). Interestingly, ovarian cancer ...