Abdul Ghaffar Department of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Pakistan
1 protocol

Yvonne Forster Department of Chemistry, University of Zurich, Switzerland
1 protocol

Stefan Bienz
  • Department of Chemistry, University of Zurich, Switzerland
Research focus
  • Plant science
  • 1 Author merit


Ph.D., Department of Chemistry, University of Zurich, Switzerland, 1989

Current position

Professor, Department of Chemistry, University of Zurich, Switzerland


  1. Forster, Y., Ghaffar, A. and Bienz, S. (2016). A new view on the codonocarpine type alkaloids of Capparis decidua. Phytochemistry 128: 50-59.
  2. Pauli, D. and Bienz, S. (2015). Regioselective solid-phase synthesis of N-mono-hydroxylated and N-mono-methylated acylpolyamine spider toxins using an 2-(ortho-nitrophenyl)ethanal-modified resin. Org Biomol Chem 13(15): 4473-4485.
  3. Pauli, D. and Bienz, S. (2014). Development of a new linker for the solid-phase synthesis of N-hydroxylated and N-methylated secondary amines. Tetrahedron 70(6): 1348-1536.
  4. Tzouros, M., Chesnov, S., Bigler, L. and Bienz, S. (2013). A template approach for the characterization of linear polyamines and derivatives in spider venom. Eur J Mass Spectrom (Chichester) 19(1): 57-69.
  5. Eichenberger, S., Meret, M., Bienz, S. and Bigler, L. (2010). Decomposition of N-hydroxylated compounds during atmospheric pressure chemical ionization. J Mass Spectrom 45(2): 190-197.
  6. Meret, M. and Bienz, S. (2008). Efficient and Flexible Solid-Phase Synthesis of N-Hydroxypolyamine Derivatives. Eur J Org Chem: 5518-5525.
  7. Bisegger, P., Manov, N. and Bienz, S. (2008). Solid-phase synthesis of cyclic polyamines. Tetrahedron 64(32): 7531-7536.
  8. Eichenberger, S., Bigler, L. and Bienz, S. (2007). Structure Elucidation of Polyamine Toxins in the Venom of the Spider Larinibides folium. Chimia 61: 161-164.
  9. Tzouros, M., Chesnov, S., Bienz, S., Hesse, M. and Bigler, L. (2005). New linear polyamine derivatives in spider venoms. Toxicon 46(3): 350-354.
  10. Bienz, S., Bisegger, P., Guggisberg, A. and Hesse, M. (2005). Polyamine Alkaloids. Nat. Prod. Rep 22: 647-658.
  11. Tzouros, M., Manov, N., Bienz, S. and Bigler, L. (2004). Tandem mass spectrometric investigation of acylpolyamines of spider venoms and their 15N-labeled derivatives. J Am Soc Mass Spectrom 15(11): 1636-1643.
  12. Tzouros, M., Bigler, L., Bienz, S., Hesse, M., Inada, A., Murata, H., Inatomi, Y., Nakanishi, T. and Darnaedi, D. (2004). Two New Spermidine Alkaloids from Chisocheton weinlandii. Helv Chim Acta 87: 1411-1425.
  13. Manov, N., Tzouros, M., Bigler, L. and Bienz, S. (2004). Solid-Phase Synthesis of 15N-Labeled Acylpentamines as Reference Compounds for the MS/MS Investigation of Spider Toxins. Tetrahedron 60: 2387-2391.
  14. Manov, N., Tzouros, M., Chesnov, S., Bigler, L. and Bienz, S. (2002). Solid-Phase Synthesis of Polyamine Spider Toxins and Correlation with the Natural Products by HPLC-MS/MS. Helv Chim Acta 2002, 85: 2827-2846.
  15. Bienz, S., Detterbeck, R., Ensch, C., Guggisberg, A., Hausermann, U., Meisterhans, C., Wendt, B., Werner, C. and Hesse, M. (2002). Putrescine, spermidine, spermine, and related polyamine alkaloids. Alkaloids Chem Biol 58: 83-338.
  16. Manov, N. and Bienz, S. (2001). A New Approach in the Solid-Phase Synthesis of Polyamine Derivatives: Construction of Polyamine Backbones from the Center. Tetrahedron 57: 7893-7898.
1 Protocol published
Chromatographic Separation of the Codonocarpine Type Alkaloids from the Root Bark of Capparis decidua
Authors:  Yvonne Forster, Abdul Ghaffar and Stefan Bienz, date: 02/20/2017, view: 5462, Q&A: 0
Various parts of the caper tree Capparis decidua have found application in traditional medicine. The isolation and structural elucidation of the codonocarpine type alkaloids contained in the root bark, however, is not trivial and has ...
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