Clifford Lowell Department of Laboratory Medicine and the Program in Immunology, University of California, USA
1 protocol
Andrea Puhar MIMS - Umeå University
40 protocols

Antoine de Morree Stanford university
33 protocols

Benoit Chassaing Georgia State University
14 protocols

Benoit Stijlemans Vrije Universiteit Brussel
4 protocols

Editor
Meenal Sinha
  • University of California
Research focus
  • Immunology
  • 1 Author merit

Education

Ph.D in Immunology, University of Texas at Houston, 2008

Current Position

Associate Specialist, University of California, San Francisco, USA

Publications

  1. Chen, J., Zhong, M. C., Guo, H., Davidson, D., Mishel, S., Lu, Y., Rhee, I., Perez-Quintero, L. A., Zhang, S., Cruz-Munoz, M. E., Wu, N., Vinh, D. C., Sinha, M., Lowell, C. A., Danska, J. S. and Veillette, A. (2017). SLAMF7 is critical receptor for phagocytosis of hematopoietic tumor cells via Mac-1 integrin-dependent mechanism. Nature.

  2. Lee, L. M., Ji, M., Sinha, M., Dong, M. B., Ren, X., Wang, Y., Lowell, C. A., Ghosh, S., Locksley, R. M. and DeFranco, A. L. (2016). Determinants of Divergent Adaptive Immune Responses after Airway Sensitization with Ligands of Toll-Like Receptor 5 or Toll-Like Receptor 9. PLoS One 11(12): e0167693.

  3. Wang, H., Li, M., Hung, C. Y., Sinha, M., Lee, L. M., Wiesner, D. L., LeBert, V., Lerksuthirat, T., Galles, K., Suresh, M., DeFranco, A. L., Lowell, C. A., Klein, B. S. and Wuthrich, M. (2016). MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase. PLoS Pathog 12(8): e1005787.

  4. Sinha, M. and Lowell, C. A. (2016). Immune Defense Protein Expression in Highly Purified Mouse Lung Epithelial Cells. Am J Respir Cell Mol Biol 54(6): 802-813.
  5. Kerr, S. C., Fischer, G. J., Sinha, M., McCabe, O., Palmer, J. M., Choera, T., Lim, F. Y., Wimmerova, M., Carrington, S. D., Yuan, S., Lowell, C. A., Oscarson, S., Keller, N. P. and Fahy, J. V. (2016). FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection. PLoS Pathog 12(4): e1005555.
  6. Deguine, J., Sinha, M., Lowell, C. A. and Barton, G. (2015). Regulation of neutrophil cytokine production during inflammation. J Immunol 194(1 Supplement): 192.21.
  7. Sinha, M., Drouin, S. M., Woodruff, T., Taylor, S. and Wetsel, R. A. (2008). The Receptor for Complement Anaphylatoxin C5a Protects Against the Development of Airway Hyperresponsiveness in Allergic Asthma by Inhibiting Cysteinyl Leukotriene Pathway. Mol Immunol 45: 4109-4110.
  8. Sinha, M., Drouin, S. M. and Wetsel, R. A. (2008). The Receptor for Complement Anaphylatoxin C5a Protects Against the Development of Airway Hyperresponsiveness in Allergic Asthma by Inhibiting Cysteinyl Leukotriene Pathway. FASEB J 22(1 Supplement): 574.2.
  9. Dillard, P., Wetsel, R. A. and Drouin, S. M. (2007). Complement C3a regulates Muc5ac expression by airway Clara cells independently of Th2 responses. Am J Respir Crit Care Med 175(12): 1250-1258.
  10. Connelly, M. A., Moulton, R. A., Smith, A. K., Lindsey, D. R., Sinha, M., Wetsel, R. A. and Jagannath, C. (2007). Mycobacteria-primed macrophages and dendritic cells induce an up-regulation of complement C5a anaphylatoxin receptor (CD88) in CD3+ murine T cells. J Leukoc Biol 81(1): 212-220.
  11. Drouin, S. M., Sinha, M., Sfyroera, G., Lambris, J. D. and Wetsel, R. A. (2006). A protective role for the fifth complement component (c5) in allergic airway disease. Am J Respir Crit Care Med 173(8): 852-857.
  12. Planque, S., Zhou, Y. X., Nishiyama, Y., Sinha, M., O'Connor-Mccourt, M., Arnett, F. C. and Paul, S. (2003). Autoantibodies to the epidermal growth factor receptor in systemic sclerosis, lupus, and autoimmune mice. FASEB J 17(2): 136-143.
  13. Sinha, M. and Molldrem, J. J. (2002). A Single Nucleotide Polymorphism in Proteinase 3 That Codes for HLA-A2-Binding Peptides Protects Against Development of Acute Myelogenous Leukemia. Blood 100(11): Abstract No 2194.
1 Protocol published
Isolation of Highly Pure Primary Mouse Alveolar Epithelial Type II Cells by Flow Cytometric Cell Sorting
Authors:  Meenal Sinha and Clifford A. Lowell, date: 11/20/2016, view: 9301, Q&A: 0
In this protocol, we describe the method for isolating highly pure primary alveolar epithelial type II (ATII) cells from lungs of naïve mice. The method combines negative selection for a variety of lineage markers along with positive selection for ...
13 Protocols reviewed
Measurement of TLR4 and CD14 Receptor Endocytosis Using Flow Cytometry
Authors:  Michael S. Schappe and Bimal N. Desai, date: 07/20/2018, view: 1176, Q&A: 0
After recognizing extracellular bacterial lipopolysaccharide (LPS), the toll-like receptor 4 (TLR4)-CD14 signaling complex initiates two distinct signaling pathways–one from the plasma membrane and the other from the signaling endosomes (Kagan et ...
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Expansion of Airway Basal Cells and Generation of Polarized Epithelium
Authors:  Hannah Levardon, Lael M. Yonker, Bryan P. Hurley and Hongmei Mou, date: 06/05/2018, view: 1526, Q&A: 1
Airway basal stem cells are the progenitor cells within the airway that exhibit the capacity to self-renew and give rise to multiple types of differentiated airway epithelial cells. This stem cell-derived epithelium displays organized architecture ...
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