Sebanta Pokhrel Stem Cell Biology Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, India
1 protocol

Prakash Baligar Amity Institute of Molecular Medicine and Stem Cell Research (AIMMSCR), Amity University, India
1 protocol

Asok Mukhopadhyay
  • Stem Cell Biology Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, India
  • 1 Author merit


Ph.D. in Biotechnology, Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology, Hauz Khas, New Delhi, 1996

Current position

Scientific Consultant, Stem Cell Biology Laboratory, National Institute of Immunology, New Delhi

Publications (since 2004)

  1. Khatri, R., Krishnan, S., Roy, S., Chattopadhyay, S., Kumar, V. and Mukhopadhyay, A. (2016). Reactive Oxygen Species Limit the Ability of Bone Marrow Stromal Cells to Support Hematopoietic Reconstitution in Aging Mice. Stem Cells Dev 25(12): 948-958.

  2. Kumar, A., Dudhal, S., Sundari, T. A., Sunkara, M., Usman, H., Varshney, A. and Mukhopadhyay, A. (2016). Dopaminergic-primed fetal liver mesenchymal stromal-like cells can reverse parkinsonian symptoms in 6-hydroxydopamine-lesioned mice. Cytotherapy 18(3): 307-319.

  3. Baligar, P., Mukherjee, S., Kochat, V., Rastogi, A. and Mukhopadhyay, A. (2016). Molecular and Cellular Functions Distinguish Superior Therapeutic Efficiency of Bone Marrow CD45 Cells Over Mesenchymal Stem Cells in Liver Cirrhosis. Stem Cells 34(1): 135-147.

  4. Kochat, V., Kanjirakkuzhiyil, S., Baligar, P., Nagarajan, P. and Mukhopadhyay, A. (2015). Donor antigen-primed regulatory T cells permit liver regeneration and phenotype correction in hemophilia A mouse by allogeneic bone marrow stem cells. Stem Cell Res Ther 6: 129.

  5. Sahu, N., Baligar, P., Midha, S., Kundu, B., Bhattacharjee, M., Mukherjee, S., Mukherjee, S., Maushart, F., Das, S., Loparic, M., Kundu, S. C., Ghosh, S. and Mukhopadhyay, A. (2015). Nonmulberry Silk Fibroin Scaffold Shows Superior Osteoconductivity Than Mulberry Silk Fibroin in Calvarial Bone Regeneration. Adv Healthc Mater 4(11): 1709-1721.

  6. Ramakrishnan, M., Mathur, S. R. and Mukhopadhyay, A. (2013). Fusion-derived epithelial cancer cells express hematopoietic markers and contribute to stem cell and migratory phenotype in ovarian carcinoma. Cancer Res 73(17): 5360-5370.

  7. Mukhopadhyay, A. (2013). Perspective on liver regeneration by bone marrow-derived stem cells-a scientific realization or a paradox. Cytotherapy 15(8): 881-892.

  8. Roy, S., Javed, S., Jain, S. K., Majumdar, S. S. and Mukhopadhyay, A. (2012). Donor hematopoietic stem cells confer long-term marrow reconstitution by self-renewal divisions exceeding to that of host cells. PLoS One 7(12): e50693.

  9. Yadav, N., Rao, S., Bhowmik, D. M. and Mukhopadhyay, A. (2012). Bone marrow cells contribute to tubular epithelium regeneration following acute kidney injury induced by mercuric chloride. Indian J Med Res 136(2): 211-220.

  10. Kaur, S., Tripathi, D., Dongre, K., Garg, V., Rooge, S., Mukopadhyay, A., Sakhuja, P. and Sarin, S. K. (2012). Increased number and function of endothelial progenitor cells stimulate angiogenesis by resident liver sinusoidal endothelial cells (SECs) in cirrhosis through paracrine factors. Hepatol 57(6): 1193-1198.

  11. Roy, S., Tripathy, M., Mathur, N., Jain, A. and Mukhopadhyay, A. (2012). Hypoxia improves expansion potential of human cord blood-derived hematopoietic stem cells and marrow repopulation efficiency. Eur J Haematol 88(5): 396-405.

  12. Yadav, N., Kanjirakkuzhiyil, S., Ramakrishnan, M., Das, T. K. and Mukhopadhyay, A. (2012). Factor VIII can be synthesized in hemophilia A mice liver by bone marrow progenitor cell-derived hepatocytes and sinusoidal endothelial cells. Stem Cells Dev 21(1): 110-120.

  13. Pati, S., Kalra, O. P. and Mukhopadhyay, A. (2011). Foe turned friend: multiple functional roles attributable to hyper-activating stem cell factor receptor mutant in regeneration of the haematopoietic cell compartment. Cell Prolif 44(1): 10-18.

  14. Khurana, S., Jaiswal, A. K. and Mukhopadhyay, A. (2010). Hepatocyte nuclear factor-4alpha induces transdifferentiation of hematopoietic cells into hepatocytes. J Biol Chem 285(7): 4725-4731.

  15. Pati, S., Gurudutta, G. U., Kalra, O. P. and Mukhopadhyay, A. (2010). The structural insights of stem cell factor receptor (c-Kit) interaction with tyrosine phosphatase-2 (Shp-2): an in silico analysis. BMC Res Notes 3: 14.

  16. Yadav, N., Kanjirakkuzhiyil, S., Kumar, S., Jain, M., Halder, A., Saxena, R. and Mukhopadhyay, A. (2009). The therapeutic effect of bone marrow-derived liver cells in the phenotypic correction of murine hemophilia A. Blood 114(20): 4552-4561.

  17. Singh, K., Srivastava, A., Mathur, N., Kumar, S., Kumar, L., Mukhopadhyay, A. and Konchupillai, V. (2009). Evaluation of four methods for processing human cord blood and subsequent study of the expansion of progenitor stem cells isolated using the best method. Cytotherapy 11(6): 768-777.

  18. Khurana, S. and Mukhopadhyay, A. (2008). Hematopoietic progenitors from early murine fetal liver possess hepatic differentiation potential. Am J Pathol 173(6): 1818-1827.

  19. Khurana, S. and Mukhopadhyay, A. (2008). In vitro transdifferentiation of adult hematopoietic stem cells: an alternative source of engraftable hepatocytes. J Hepatol 49(6): 998-1007.

  20. Khurana, S. and Mukhopadhyay, A. (2007). Characterization of the potential subpopulation of bone marrow cells involved in the repair of injured liver tissue. Stem Cells 25(6): 1439-1447.

  21. Mangla, A., Khare, A., Vineeth, V., Panday, N. N., Mukhopadhyay, A., Ravindran, B., Bal, V., George, A. and Rath, S. (2004). Pleiotropic consequences of Bruton tyrosine kinase deficiency in myeloid lineages lead to poor inflammatory responses. Blood 104(4): 1191-1197.

  22. Madhusudhan, T., Majumdar, S. S. and Mukhopadhyay, A. (2004). Degeneration of stroma reduces retention of homed cells in bone marrow of lethally irradiated mice. Stem Cells Dev 13(2): 173-182.

1 Protocol published
Experimental Liver Fibrosis and Intrasplenic Transplantation of CD45+ Bone Marrow Cells
Authors:  Prakash Baligar, Sebanta Pokhrel and Asok Mukhopadhyay, date: 10/20/2016, view: 2820, Q&A: 0
Liver fibrosis results from the excessive collagen deposition (collagen scar) by activated hepatic stellate cells (HpSCs), leading to the inhibition of normal liver regeneration and function. Fibrogenesis is a complex mechanism involving both the ...