Chia-Yang Liu School of Optometry, Indiana University, USA
1 protocol

Lingling Zhang School of Optometry, Indiana University, USA
1 protocol

Okada Yuka School of Optometry, Indiana University, USA
1 protocol

Yen-Chiao Wang School of Optometry, Indiana University, USA
1 protocol

Yujin Zhang
  • School of Optometry, Indiana University, USA
Research focus
  • Cell biology
  • 1 Author merit


Ph. D. in Philosophy, School of Life Science, Southwest University, 1998

Current position

Associate Scientist, School of Optometry, Indiana University

Editorial Review Board member of Chinese Medical Journal

Publications (Selected)

  1. Zhang, Y. and Liu, C. Y. (2016). ALK5, A Novel Binding Partner of Lumican in Corneal Wound Healing. Biochem Ana Biochem.

  2. Zhang, Y., Yeh, L. K., Zhang, S., Call, M., Yuan, Y., Yasunaga, M., Kao, W. W. and Liu, C. Y. (2015). Wnt/beta-catenin signaling modulates corneal epithelium stratification via inhibition of Bmp4 during mouse development. Development 142(19): 3383-3393.

  3. Dong, F., Liu, C. Y., Yuan, Y., Zhang, Y., Li, W., Call, M., Zhang, L., Chen, Y., Liu, Z. and Kao, W. W. (2015). Perturbed meibomian gland and tarsal plate morphogenesis by excess TGFalpha in eyelid stroma. Dev Biol 406(2): 147-157.

  4. McCauley, H. A., Liu, C. Y., Attia, A. C., Wikenheiser-Brokamp, K. A., Zhang, Y., Whitsett, J. A. and Guasch, G. (2014). TGFbeta signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium. Development 141(23): 4628-4639.

  5. Yang, D., Sun, Y. Y., Bhaumik, S. K., Li, Y., Baumann, J. M., Lin, X., Zhang, Y., Lin, S. H., Dunn, R. S., Liu, C. Y., Shie, F. S., Lee, Y. H., Wills-Karp, M., Chougnet, C. A., Kallapur, S. G., Lewkowich, I. P., Lindquist, D. M., Murali-Krishna, K. and Kuan, C. Y. (2014). Blocking lymphocyte trafficking with FTY720 prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns. J Neurosci 34(49): 16467-16481.

  6. Zhang, Y., Lam, O., Nguyen, M. T., Ng, G., Pear, W. S., Ai, W., Wang, I. J., Kao, W. W. and Liu, C. Y. (2013). Mastermind-like transcriptional co-activator-mediated Notch signaling is indispensable for maintaining conjunctival epithelial identity. Development 140(3): 594-605.

  7. Ng, G. Y., Yeh, L. K., Zhang, Y., Liu, H., Feng, G. S., Kao, W. W. and Liu, C. Y. (2013). Role of SH2-containing tyrosine phosphatase Shp2 in mouse corneal epithelial stratification. Invest Ophthalmol Vis Sci 54(13): 7933-7942.

  8. Yuan, Y., Call, M. K., Yuan, Y., Zhang, Y., Fischesser, K., Liu, C. Y. and Kao, W. W. (2013). Dexamethasone induces cross-linked actin networks in trabecular meshwork cells through noncanonical wnt signaling. Invest Ophthalmol Vis Sci 54(10): 6502-6509.

  9. Yamanaka, O., Yuan, Y., Coulson-Thomas, V. J., Gesteira, T. F., Call, M. K., Zhang, Y., Zhang, J., Chang, S. H., Xie, C., Liu, C. Y., Saika, S., Jester, J. V. and Kao, W. W. (2013). Lumican binds ALK5 to promote epithelium wound healing. PLoS One 8(12): e82730.

  10. Zhang, Y., Kao, W. W., Pelosi, E., Schlessinger, D. and Liu, C. Y. (2011). Notch gain of function in mouse periocular mesenchyme downregulates FoxL2 and impairs eyelid levator muscle formation, leading to congenital blepharophimosis. J Cell Sci 124(Pt 15): 2561-2572.

  11. Zhang, Y., Call, M. K., Yeh, L. K., Liu, H., Kochel, T., Wang, I. J., Chu, P. H., Taketo, M. M., Jester, J. V., Kao, W. W. and Liu, C. Y. (2010). Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea. J Cell Sci 123(Pt 8): 1285-1294.

  12. Weng, D. Y., Zhang, Y., Hayashi, Y., Kuan, C. Y., Liu, C. Y., Babcock, G., Weng, W. L., Schwemberger, S. and Kao, W. W. (2008). Promiscuous recombination of LoxP alleles during gametogenesis in cornea Cre driver mice. Mol Vis 14: 562-571.

  13. Wang, M., Zhang, Y. and Wang, X. J. (2008). Extracellular Ca2+ and cell membrane components involved in anthocyanin accumulation induced by blue light in Arabidopsis thaliana. Acta Biophysica Sinica 24(6): 452-459.

1 Protocol published
Mouse Corneal Stroma Fibroblast Primary Cell Culture
Authors:  Yujin Zhang, Yen-Chiao Wang, Okada Yuka, Lingling Zhang and Chia-Yang Liu, date: 10/05/2016, view: 5986, Q&A: 0
This protocol is developed for primary cell culture of cornea stromal keratocytes isolated from neonatal mouse eyeballs. It provides an optimal condition to isolate stromal keratocytes which maintain high viability for cell culture.
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